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(Click for frequent words.) 69 pharmacodynamic parameters 69 pharmacodynamic markers 68 antitumor effect 68 chemosensitivity 68 HER2 expression 68 molecular biomarkers 67 K ras mutations 67 SELDI TOF MS 67 glycosylated hemoglobin HbA1c 67 tryptase 67 immunohistochemical analysis 66 CD# expression [001] 66 DNA methylation patterns 66 methylation markers 66 microRNA biomarkers 66 serum lipid 66 amyloid plaque formation 66 biochemical abnormalities 66 plasma pharmacokinetics 66 mTOR inhibition 66 APOE genotype 66 biomarker identification 66 intact parathyroid hormone 66 RRM1 66 differential gene expression 66 hepatic fibrosis 66 metabolomic profiling 66 metabolite concentrations 66 lactate dehydrogenase LDH 66 TPMT 66 prognostic indicators 66 carcinoembryonic antigen 66 antiangiogenic agents 66 Cystatin C 66 pharmacodynamic effects 66 etiologic 66 transgene expression 66 telomerase activation 66 splice variants 65 eTag assays 65 p# activation 65 molecular determinants 65 serum markers 65 Haptoglobin 65 immunohistochemical 65 biodistribution 65 immunofluorescent 65 redox active 65 malondialdehyde MDA 65 antiangiogenic therapy 65 Corus CAD 65 synthetic lethality 65 prognostic markers 65 antiproliferative effects 65 PCA3 gene 65 plasma lipid 65 prostate cancer CaP 65 HER2 overexpression 65 induced sputum 65 miRNA expression 65 genetic polymorphisms 65 pharmacokinetic characteristics 65 p# antigen 65 p# biomarkers 65 bioactivity 65 p# biomarker 65 telomerase inhibition 65 tumorigenicity 65 ADME properties 64 Clusterin 64 specific antigen PSA 64 anticancer activity 64 preclinically 64 flavopiridol 64 protein excretion 64 sarcosine 64 F FDG PET 64 meta regression 64 mitochondrial toxicity 64 immunological responses 64 Subgroup analysis 64 metaplasia 64 metabolomic 64 HIF PH inhibitors 64 vivo potency 64 ABL1 64 EGFR inhibition 64 natriuretic peptides 64 CYT# potent vascular disrupting 64 nomograms 64 MTT assay 64 prostate cancer PCa 64 Akt activation 64 cytologic 64 P2V TM 64 Squalamine 64 antagomirs 64 silico prediction 64 β carotene 64 N glycan 64 oxidative stress markers 64 Cotinine 64 homocysteine concentrations 64 differentially expressed proteins 64 KRAS mutation 64 serum BDNF 64 PITX2 64 antiangiogenic activity 64 biochemical markers 64 metabolomic profiles 64 Multivariate logistic regression 64 GPx 64 molecular biomarker 64 PARP inhibition 64 oxysterols 64 phenotypic expression 63 sensitivity specificity 63 murine models 63 pre malignant lesions 63 Cardiotoxicity 63 demonstrated antitumor activity 63 immunostaining 63 diagnostic biomarker 63 plasma renin activity 63 pathogenetic mechanisms 63 MTHFD1L gene 63 E. faecalis 63 NPM1 mutation 63 LSI #P 63 antioxidant supplementation 63 tumor hypoxia 63 inflammatory biomarkers 63 Tr DNA 63 thyrotropin 63 Non inferiority 63 uricase 63 ERK signaling 63 soluble CD# ligand 63 Trofex 63 convergent validity 63 breast cancer subtypes 63 novel VDA molecule 63 pharmacodynamic profiles 63 H. pylori eradication 63 ELISpot 63 p tau 63 pharmacokinetic parameters 63 cisplatin resistant 63 plasma proteome 63 OnDose TM 63 selenium supplementation 63 Darapladib 63 cTnI 63 abnormal glucose metabolism 63 RT qPCR 63 prostate carcinoma 63 Phenotypic 63 murine model 63 serum PSA 63 genomic biomarker 63 albumin excretion 63 epistasis 63 genotypic resistance 63 genotypic 63 obstructive coronary artery 63 p# INK4a 63 plasma lipoprotein 63 physico chemical properties 63 glial tumors 63 Immunohistochemical analysis 63 busulfan 63 cardioprotective effects 63 phosphorylated tau 63 tolerability pharmacokinetics 63 tumor subtypes 63 indibulin 63 microRNA profiling 63 beta1 integrin 63 metastatic lymph nodes 63 pleiotropic effects 63 autoantibody levels 63 florbetaben 63 choroidal vasculopathy 63 endothelial activation 63 ADAMTS# 63 molecular abnormalities 63 thyrotropin levels 63 Genotypic 63 differentially expressed genes 63 platelet activation 63 mediated inhibition 63 Multiple logistic regression 63 spectrophotometric 63 urate levels 63 SiMoA 63 SSc 63 HIV tropism 63 transcriptomic 63 intracellular uptake 63 deCODE BreastCancer TM 62 cytotoxicity assays 62 HERmark assay 62 STRIDE PD 62 biomarkers 62 micronuclei 62 apolipoprotein B 62 myocardial necrosis 62 colorectal adenoma 62 genomic biomarkers 62 validate biomarkers 62 antigen PSA levels 62 histopathological 62 antitumor efficacy 62 clinicopathological 62 proton MR spectroscopy 62 hydroxy vitamin D 62 CP CPPS 62 genetic biomarkers 62 mutated K ras 62 aminotransferase levels 62 LRP5 62 Lp PLA 2 62 neutrophil gelatinase associated lipocalin 62 lactate dehydrogenase 62 sitosterol 62 pharmacogenetic testing 62 bFGF 62 biomarker 62 miR #a [001] 62 epigenetic markers 62 MAGE A3 ASCI 62 bronchial hyperresponsiveness 62 urinary excretion 62 fosbretabulin 62 sirtuin activators 62 transcriptomics 62 breast endometrial 62 liver metastasis 62 IgG antibody 62 serum homocysteine 62 PSMA ADC 62 Azedra 62 pharmacodynamic properties 62 neuroprotective effects 62 immunomodulation 62 APTIMA HPV 62 haematologic 62 quasispecies 62 kidney urologic 62 #F FDG PET 62 antiplatelet therapies 62 deCODE ProstateCancer TM 62 Epigenomics proprietary 62 Genetic variation 62 Hp2 2 62 VKORC1 62 gastric adenocarcinoma 62 conditional logistic regression 62 residual confounding 62 viral tropism 62 EGFR mutation status 62 HIV HCV coinfected 62 Tß4 62 plasma triglycerides 62 Darinaparsin 62 subcellular compartments 62 atherogenic dyslipidemia 62 chromosomal anomalies 62 CTAP# Capsules 62 biochemical marker 62 trans palmitoleate 62 metastatic neuroendocrine tumors 62 #S rRNA gene 62 TRAIL R1 62 prognostic biomarkers 62 perfusion MRI 62 p# Shc 62 dose proportionality 62 neovascular 62 Vidaza ® 62 collagen degradation 62 serum urate levels 62 ApoA l 62 myeloperoxidase 62 physiologic mechanisms 62 nutlin 3a 62 endoglin 62 multiplex assay 62 MGd 62 FDG PET imaging 62 preclinical pharmacokinetic 62 lung epithelium 62 CD# expression [002] 62 motor neuron degeneration 62 hypericin 62 AGHD 62 TMPRSS2 ERG fusion 62 biomolecular interactions 62 AST ALT 62 FDG uptake 62 semiquantitative 62 Onconase 62 anti CD3 62 glutamyl 62 kallikrein 62 5alpha reductase 62 Pharmacodynamic 62 genotoxicity 62 microRNA expression 62 epithelial tumors 62 Immunohistochemical 62 ß amyloid 62 KRAS status 62 endophenotypes 62 enzyme immunoassay EIA 62 radiation dosimetry 62 BACcel ™ system 62 metabonomics 62 serum cortisol 62 cystatin 62 urinary albumin 62 hematological parameters 62 developmental neurotoxicity 62 HbF 62 proteoglycan 62 genetic loci 62 RQ PCR 62 gene expression microarrays 62 Cardiorespiratory fitness 62 autoimmune pancreatitis 62 trastuzumab Herceptin ® 62 Cyclin E 62 pharmacogenetic tests 62 immunostimulatory effects 62 S/GSK# 62 eosinophil count 62 C telopeptide 62 transferrin saturation 62 favorable pharmacokinetic 62 echocardiographic parameters 61 qRT PCR 61 lymphoid tumors 61 ptau 61 arterial thickening 61 UGT#A# 61 scintigraphic 61 miRNA biomarkers 61 mRNA expression 61 Histopathologic 61 CYP#D# genotype 61 phenotypic variation 61 serum concentrations 61 Symadex 61 EDEMA3 trial 61 peripheral insulin sensitivity 61 polyamines 61 cardiac troponin T 61 favorable pharmacokinetic profile 61 chemopreventive agent 61 A3 adenosine receptor 61 nucleotide substitutions 61 aminotransferase 61 methylation patterns 61 mammographically 61 prostate carcinogenesis 61 nucleosome positioning 61 interleukin IL -6 61 myocardial viability 61 ALA PDT 61 HOMA IR 61 pharmacokinetic interactions 61 intestinal permeability 61 chromosomal aberrations 61 Her2/neu 61 antiangiogenic 61 genetic determinants 61 glomerular filtration 61 immunohistochemical staining 61 imatinib resistance 61 siRNA conjugates 61 eicosanoid 61 Lipoic acid 61 MSMB 61 Mass Spectrometry MS 61 recurrent venous thromboembolism 61 sirtuin enzymes 61 platelet dysfunction 61 Elevated serum 61 riociguat 61 PHD2 61 hypermethylated 61 specific IgE 61 bezafibrate 61 pathophysiological effects 61 cardiac repolarization 61 pharmacodynamic PD 61 galiximab 61 efaproxiral 61 toxicogenomic 61 rhITF 61 carotid bruit 61 biologic pathways 61 mGluR2 NAM 61 periprocedural MI 61 pCR 61 NSCLC tumors 61 HNSCC 61 B7 H3 61 renoprotective 61 subclinical atherosclerosis 61 serum phosphate 61 curcuminoids 61 mechanistic insights 61 Factor Receptor 61 Thalomid ® 61 #ME# 61 BRAF mutation 61 8 OHdG 61 tumor histology 61 β1 61 myocardial infarct size 61 histologic subtype 61 PET tracers 61 GAMMAGARD 61 extramedullary 61 urine cytology 61 autoantigens 61 ADVEXIN therapy 61 Prognostic factors 61 Leydig cell 61 peroxidation 61 sequence homology 61 allogeneic HSCT 61 bronchoalveolar 61 leukocyte count 61 urothelial cancer 61 genomic proteomic 61 γ secretase 61 fructosamine 61 Western blotting 61 prognostic marker 61 genomewide 61 percutaneous biopsy 61 colorectal neoplasia 61 HAAH 61 paricalcitol 61 sDNA 61 synovial cells 61 protein albumin 61 MEK ERK 61 Aspergillus nidulans 61 postprandial glycemia 61 Histopathological 61 pancreatic prostate 61 viral titers 61 immunochemical 61 inhibit metastasis 61 neuropsychiatric diseases 61 mimetics 61 airway hyperresponsiveness 61 isotypes 61 DNA methylation markers 61 psychosocial variables 61 druggable targets 61 pulmonary toxicity 61 CCX# 61 hematopoietic cancers 61 colorectal tumor 61 arterial calcification 61 serum PTH 61 vascular disrupting agents 61 relapsed MM 61 rhIGFBP 3 61 proliferative disorders 61 atherothrombotic 61 gene expression biomarkers 61 multiple logistic regression 61 proteomic analysis 61 chemopreventive agents 61 HCV replication 61 antiangiogenic agent 61 metaglidasen 61 promoter hypermethylation 61 INS# [001] 61 pressure natriuresis 61 radiolabeled 61 nanomolar 61 β amyloid 61 oral JAK1 61 ON #.Na 61 anti androgens 61 vascular disrupting 61 physicochemical 61 co receptor tropism 61 anti amnesic 61 binding affinities 61 parthenolide 61 CSF biomarkers 61 genomic alterations 61 plasma homocysteine 61 NPRL2 61 microglial activation 61 natriuretic peptide 61 immunotoxins 61 carotid plaque 61 IgE antibody 61 mucinous 61 aminotransferases 61 metabolite identification 61 EGFR HER 61 pain palliation 61 potency selectivity 61 Nanobacteria 61 aortic stiffness 61 d dimer 61 circulating endothelial cells 61 PROSTVAC VF 61 immune modulating 61 multivariate Cox 61 cells MSCs 61 aggregated Abeta 61 KRAS mutations 61 gastric carcinoma 61 teratogenicity 61 mtDNA mutations 61 thyroid carcinoma 61 transient elastography 61 elevated homocysteine 61 HER-2/neu protein 61 endometrial hyperplasia 61 macrophage infiltration 61 #T# L1 61 LT NS# 61 histone modifications 61 chromosomal mutations 61 XL# inhibits 61 adjuvant therapies 61 gastrointestinal stromal tumors GISTs 61 airway responsiveness 61 anti atherogenic 61 carbohydrate polymers 61 genetic aberrations 61 T#I [002] 61 APOPTONE 61 viral kinetics 61 flow cytometric 61 allele frequencies 61 VEGF expression 61 gastric carcinomas 61 bronchoalveolar lavage fluid 61 VeriStrat 61 glycated hemoglobin levels 61 immunoblotting 61 monogenic 61 HDAC inhibition 61 immunofluorescence microscopy 61 hepatic enzymes 61 RBP4 61 serotonin synthesis 61 FGFs 61 heparanase 61 bladder tumors 61 therapeutic regimens 61 alkaline phosphatase ALP 61 biomarker assay 61 pharmacologic approaches 61 metabolic disturbances 61 CYP#C# [002] 61 ConclusionThis 61 TOMM# 61 NS#/#A protease 61 prostanoid 61 hypoxic tumors 61 neutrophil counts 61 blood coagulation disorders 61 gefitinib Iressa 61 Mechanistic studies 61 LDL cholesterol concentrations 61 prognostic indicator 61 CYP#C# genotype 60 pathophysiological mechanisms 60 neuro protective 60 PhG alpha 1 60 hepatocellular carcinoma liver 60 chromosome aberrations 60 intensive lipid lowering 60 circadian genes 60 putative biomarkers 60 OGG1 60 CBLC# 60 metabolic parameters 60 spirometric 60 microalbumin 60 AV HALT 60 thromboxane A2 60 impaired insulin secretion 60 splice junctions 60 invasive lobular 60 underlying molecular mechanisms 60 thyroglobulin 60 Genetic variations 60 diabetic kidney 60 intravascular hemolysis 60 lipid lowering therapies 60 Neuropsychiatric Inventory NPI 60 HCV replicon 60 Psoraxine R 60 tNOX 60 membrane permeability 60 cystatin C 60 immuno modulatory 60 Beta Amyloid 60 alpha fetoprotein AFP 60 HDL Selective Delipidation 60 EGFR tyrosine kinase inhibitors 60 unresectable tumors 60 modifier genes 60 EGFR HER2 60 leiomyoma 60 ENMD # 60 selective inhibition 60 clinico pathological 60 siRNA knockdown 60 CCR1 60 silibinin 60 mTOR inhibitors 60 Fc gamma receptor 60 cAMP signaling 60 alpha1 antitrypsin deficiency 60 plasma lipids 60 OMP #M# 60 serum calcium 60 Eg5 60 compound AEZS 60 Anticalins ® 60 Epidemiologic studies 60 tumoral 60 pharmacodynamic endpoints 60 Squamous 60 inhibitory effects 60 tumor biopsies 60 triglyceride concentrations 60 histone acetylation 60 glycosylated hemoglobin levels 60 Oxidative damage 60 Angiotensin converting enzyme 60 central corneal thickness 60 missense mutations 60 PI3K/Akt pathway inhibitor 60 Skeletal muscle 60 DFMO 60 HER2 positivity 60 ImmuKnow 60 experimentally induced 60 antiangiogenesis 60 clinically insignificant 60 thyroid stimulating hormone 60 CyPath ® assay 60 antisense inhibitors 60 immunochemical fecal occult 60 hepatoma 60 extrapyramidal symptoms 60 antitumour 60 arterial inflammation 60 bryostatin 60 SIRT1 activation 60 MDRD 60 #beta HSD1 60 prospectively defined 60 inhibin B 60 isoprostane 60 FGFR2 gene 60 ERK1 2 60 PhenoSense GT 60 iron chelators 60 Alpha lipoic acid 60 genetic variants associated 60 FISH fluorescence 60 small molecule activators 60 mevalonate 60 CYP#D# gene 60 SELDI TOF 60 neurocognitive function 60 diagnostic prognostic 60 diabetic microvascular complications 60 intraobserver 60 TLR9 agonists 60 fasting triglycerides 60 endoxifen 60 malignant nodules 60 Prostate Cancer Progression 60 spermidine 60 protein microarrays 60 precursor lesions 60 neurodevelopmental outcome 60 lipoprotein metabolism 60 Flow cytometry 60 methylated DNA 60 adrenocortical cancer 60 HERmark 60 fumagillin nanoparticles 60 coronary stenosis 60 tissue oxygenation 60 cardiovascular morbidity 60 pyridostigmine 60 interobserver 60 Panzem 60 coagulation abnormalities 60 immunomodulatory properties 60 probiotic supplementation 60 troponins 60 fibrotic disease 60 platelet reactivity 60 TÎ ² 4 60 thymidylate synthase TS 60 histone deacetylases 60 serum uric acid 60 glucagon receptor 60 GAGs 60 N telopeptide 60 genetic polymorphism 60 familial aggregation 60 ADAS Cog 60 chlamydial 60 cDNA microarray 60 biopsied tissue 60 ApoA1 60 potent suppressor 60 radiosensitivity 60 prognostic variables 60 renal cell carcinomas 60 predictive biomarkers 60 carotid IMT 60 serum lipid levels 60 mecamylamine 60 antigen PSA 60 QTc prolongation 60 abacavir Ziagen 60 PROCHYMAL 60 Masimo SpHb 60 radioimmunoassay 60 p# MAPK 60 carbonyls 60 nodal metastasis 60 mesothelin 60 antidepressant efficacy 60 CD#c 60 genes differentially expressed 60 cerebrospinal fluid CSF 60 virulence genes 60 hyperphenylalaninemia HPA due 60 IL#B 60 STAT3 signaling 60 pharmacodynamic biomarkers 60 intermittent hypoxia 60 plasma kallikrein 60 delafloxacin 60 transfection efficiency 60 endoplasmic reticulum stress 60 complement inhibitor eculizumab 60 immunoregulatory 60 pleiotropy 60 HepG2 cells 60 interleukin IL -# 60 miRview ™ squamous 60 TIMP 1 60 hypercalciuria 60 pharmacokinetic PK profile 60 alkylating 60 CYP#A# CYP#D# 60 Annexin V 60 monoclonal gammopathy 60 Virulizin ® 60 Primary endpoints 60 Secondary efficacy endpoints 60 PROLARIS 60 pyrimidines 60 growth hormone secretion 60 adrenal function 60 TLE3 60 cryptoxanthin 60 serologic 60 Meta analyzes 60 pathogenic mutations 60 adducts 60 surrogate markers 60 intestinal mucosal 60 gene amplification 60 colorectal carcinoma 60 nonfasting triglyceride levels 60 Histologic 60 enzyme cofactor 60 AGTR1 60 HuLuc# 60 therapeutic monoclonal antibody 60 cMET 60 meta analytic 60 electron beam computed tomography 60 C Reactive Protein 60 microsatellite instability 60 serum leptin 60 cardiac troponin 60 biologic pathway 60 hyperinsulinemic euglycemic clamp 60 multivariable analysis 60 caspofungin 60 antimetabolites 60 apolipoprotein A1 60 tumor subtype 60 peritoneal fluid 60 pleiotropic 60 bone scintigraphy 60 genomic markers 60 NB S# strontium malonate 60 macroalbuminuria 60 TMPRSS2 ERG 60 causative mutations 60 histone deacetylase HDAC 60 factor PlGF 60 transcranial Doppler ultrasound 60 ovarian endometrial 60 Fulvestrant 60 serum lipids 60 BMS# 60 PM#.# exposure 60 liver fibrosis 60 pharmacokinetic equivalence 60 non nucleoside 60 Soy isoflavones 60 antitumour activity 60 methodologic 60 nonclinical studies 60 SpCO 60 albumin excretion rate 60 unmeasured confounders 60 hERG 60 MDRD equation 60 HER2 amplification 60 c reactive protein 60 CYP#C# [001] 60 fibrin deposition 60 vitro assay 60 bile acid metabolism 60 gp# protein [002] 60 Protein Kinase C 60 4E BP1 60 ADAGIO study 60 leukotriene B4 60 oral prodrug 60 CYP#B# 60 protein tyrosine phosphatase 1B 60 Hyperlipidemia 60 anti JCV antibodies 60 nephrotoxicity 60 ncRNA 60 Superoxide 60 biochemical assays 60 prognostically 60 preclinical efficacy 60 renal toxicity 60 somatic mutations 60 miRview mets 60 KRAS mutation status 60 Genetic variants 60 radiolabeled TM# 60 amyloidogenic 60 metabolic alterations 60 causal variants 60 hemoglobin A1c HbA1c 60 physicochemical properties 60 prognostic biomarker 60 quantitative RT PCR 60 ABCB1 59 lupus anticoagulant 59 Upregulation 59 axonal degeneration 59 amyloid deposition 59 ALV# 59 CCR3 59 C. pneumoniae 59 multivariate logistic regression 59 systemically administered 59 G6PD deficiency 59 EGFR pathway 59 chromosomal rearrangement 59 familial clustering 59 iTRAQ 59 prognostic significance 59 hPTH #-# 59 phosphate S1P 59 non pharmacological interventions 59 protein tyrosine phosphatases 59 antigenic epitopes 59 miRs 59 biomarker validation 59 SERMs 59 Infinium assay 59 deacetylase inhibitors 59 KIAA# 59 fatty acid oxidation 59 bronchoalveolar lavage 59 clusterin 59 granulocyte 59 posttranslational modifications 59 xenograft models 59 antigenicity 59 transcriptomics proteomics 59 histologic subtypes 59 QRT PCR 59 alemtuzumab MS 59 Mass spectrometry 59 PKCi 59 cyclic AMP cAMP 59 fusion enhancers 59 elastase 59 Viral load 59 MetAP2 59 Kaplan Meier method 59 presymptomatic 59 DHEA supplementation 59 Hedgehog inhibitor 59 beta carotene supplementation 59 protein tyrosine phosphatase 59 PIK3CA 59 epithelial barrier 59 serum clusterin levels 59 serum protein biomarkers 59 leukocyte counts 59 hamartomas 59 JAK inhibitors 59 NMDA antagonists 59 inhibit platelet aggregation 59 E selectin 59 Treg cell 59 PLAC test 59 transthyretin 59 chemopreventive 59 intima media thickness 59 underlying pathophysiology 59 riboflavin vitamin B2 59 lesional 59 Nexrutine 59 biostatistical analysis 59 eNO 59 genes CYP#C# 59 epigallocatechin 59 biologic plausibility 59 HLA DRB1 59 hMG 59 erythropoietic 59 protein biomarkers 59 pan HDAC inhibitor 59 serous ovarian cancer 59 enterotypes 59 platform HDL Mimetic 59 serum IgE 59 VerifyNow 59 GRNCM1 59 INCB# [001] 59 antiresorptive 59 triacylglycerol concentrations 59 receptor subtypes 59 PIGF 59 cytotoxicity 59 AEG# 59 CINtec ® PLUS 59 metaanalysis 59 ANGPTL4 59 apo B 59 creatinine ratio 59 Ki# 59 baseline LDH 59 bone metabolism 59 papillary renal cell carcinoma 59 angiographically 59 Cytogenetic 59 PRESEPT study 59 culture supernatants 59 ductal carcinomas 59 alvespimycin 59 thiopurine 59 Septin 9 59 MMP# 59 lung metastasis 59 NNRTI resistance 59 EUS FNA 59 interstitial fluid 59 Safinamide 59 Dr. Bezprozvanny 59 PTEN protein 59 microwell plate 59 small molecule agonists 59 anti angiogenic drugs 59 FUSILEV enhances 59 CIN2 + 59 thrombogenic 59 cTnT 59 induced oxidative stress 59 GAP #B#