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(Click for frequent words.) 73 RNAi mediated 71 tyrosine phosphorylation 71 antiapoptotic 70 adenosine receptor 70 ERK1 2 69 Cdc7 69 β catenin 69 siRNA knockdown 69 cytokine signaling 69 mitogen activated protein kinase 69 virulence genes 68 UsiRNAs 68 HIF 1alpha 68 short hairpin RNA 68 FasL 68 pleiotropic 68 intracellular signaling 68 E#F# 68 NS5A 68 PI3K Akt 68 shRNA 68 thymidylate synthase TS 68 Protein Kinase C 68 immunostimulatory 67 p# MAPK 67 TGF ß 67 CDK inhibitor 67 muscarinic 67 IL 1ß 67 EGF receptor 67 γ secretase 67 MAPK pathway 67 MEK1 67 lysosomal 67 miR #a [002] 67 HIF 1a 67 p# activation 67 effector function 67 androgen receptor AR 67 c MYC 67 IL 1β 67 eIF4E 67 Flt3 67 HDAC6 67 CEACAM1 67 Htt 67 estrogen receptor beta 67 costimulatory 67 VEGF receptor 67 Hypoxia Inducible Factor 67 chemokine receptor 67 cAMP signaling 67 PTP 1B 67 miR #a [001] 67 survivin 67 Nedd4 67 selective inhibition 66 eNOS 66 splice variants 66 antisense oligonucleotides 66 hTERT 66 phosphatases 66 DNA methyltransferases 66 ghrelin receptor 66 NKG2D 66 glucocorticoid receptor 66 MAP kinase 66 ErbB3 66 ligase 66 kinase inhibition 66 tumorigenicity 66 DLC1 66 adipogenic 66 serine threonine kinase 66 TTR gene 66 activin 66 DNA demethylation 66 DNMT1 66 pRb 66 glycosylated 66 Fc receptor 66 transcriptional activation 66 Jhdm2a 66 occludin 66 GPR# [002] 66 cytoprotective 66 catenin 66 SIRT2 66 transgene expression 66 uPAR 66 E1A 66 ENMD # 66 FGFR3 66 serine protease 66 PKM2 66 potent inhibition 66 Notch1 66 IFN gamma 66 casein kinase 66 NS4A 66 transfected cells 65 SCD1 65 Akt activation 65 HCV replication 65 STAT1 65 histone deacetylases 65 Clusterin 65 anti CD3 65 Symadex 65 Upregulation 65 ENaC 65 FGFR 65 VE cadherin 65 potent anti angiogenic 65 protein tyrosine phosphatase 1B 65 DiLA2 liposomes 65 humoral 65 MT1 MMP 65 acetylcholine receptor 65 gene inactivation 65 c MET 65 cyclin dependent kinases 65 CD1d 65 constitutively active 65 HDAC 65 immunoregulatory 65 M1 muscarinic 65 GSK3B 65 Hedgehog signaling 65 IFN γ 65 nicotinic acetylcholine receptor 65 BCR ABL 65 ubiquitylation 65 TNFα 65 proteolysis 65 T#I [002] 65 FUS1 65 TGF beta1 65 PKC isoforms 65 #β HSD1 65 shRNAs 65 iNOS 65 anionic backbone 65 HDAC inhibition 65 siRNA therapeutic 65 NKT cell 65 Eg5 65 ERK pathway 65 fibrotic disease 65 HDACi 65 NF kappaB 65 pro angiogenic 65 Smoothened 65 glycolytic 65 Androgen receptor 65 hypoxia inducible factor 65 JAK#/JAK# 65 IAP inhibitor 65 Mutational 65 BMAL1 65 short hairpin RNAs 65 p# mitogen activated 65 PPARg 65 Nampt 65 CDKs 65 ribonuclease 65 rhIL 7 65 IGF 1R 65 RNA silencing 65 NMDAR 65 tyrosine kinase 65 AT1R 65 NFkB 65 5 HT4 receptor 65 coactivator 65 microglial 65 p# subunit 64 enzymatic activity 64 KLF4 64 CTGF 64 NKX#.# 64 HER3 64 NR2B subunit 64 serine threonine 64 NF κB 64 TGFβ 64 MEK ERK 64 ERK activation 64 transcriptional regulation 64 phagocytosis 64 PDGFR 64 dsRNA 64 targeting CD# 64 selectively inhibited 64 Anticalins ® 64 CXCR7 64 downregulation 64 RAS RAF MEK 64 p#Kip# 64 pDCs 64 COX2 64 transcriptional repressor 64 Galectin 64 replicon 64 receptor mediated 64 RAR beta 64 tumor antigen 64 histone deacetylase HDAC 64 Lyn kinase 64 JNK1 64 JAK STAT 64 ubiquitination 64 prostaglandin synthesis 64 oxidative phosphorylation 64 chemokine 64 miR #b [002] 64 methyltransferases 64 antitumor 64 HCV protease 64 TNFalpha 64 cellular pathways 64 c Src 64 T#M 64 downstream effectors 64 Cyclin E 64 Rho GTPase 64 microglial activation 64 neurite outgrowth 64 siRNA duplexes 64 receptor subtypes 64 CRAC channel 64 MyoD 64 tyrosine kinase inhibitor 64 ErbB3 HER3 64 Fc fusion protein 64 IgG1 64 mediated inhibition 64 FLT3 64 Gleevec resistant 64 Aurora kinase 64 apoptotic pathway 64 telomerase reverse transcriptase 64 Wnt beta catenin 64 noncoding RNA 64 Cyclin D1 64 PDGF receptor 64 deacetylation 64 protein tyrosine phosphatases 64 Dysregulation 64 antiproliferative activity 64 PHD2 64 renal fibrosis 64 STAT3 64 neuropilin 64 vitro assay 64 c myc 64 TLE3 64 CTLs 64 osteoclast 64 TGF β 64 thyroid hormone receptor 64 splice variant 64 Histone 64 oncoprotein 64 proteolytic cleavage 64 lysophosphatidic acid LPA 64 P cadherin 64 vascular disrupting agents 64 TrkB 64 JAK2 64 Interferon gamma 64 phosphoprotein 64 Janus kinase 64 PI3K/Akt pathway 64 RT qPCR 64 prostaglandin E2 PGE2 64 overactivation 64 GPx 64 costimulation 64 TNFa 64 EGFr 64 ADAM# 64 ectopic expression 64 TAp# 64 NF kappaB activation 64 anaphase promoting complex 64 Cathepsin B 63 P2X 63 Aurora Kinase 63 NS3 protease 63 TNF α 63 histone acetyltransferase 63 induce apoptosis 63 mda 7 63 ubiquitin ligase 63 vimentin 63 antibody mediated 63 antisense oligonucleotide 63 ERBB2 63 antisense molecules 63 ß catenin 63 drug metabolizing enzymes 63 proto oncogene 63 Liposomal 63 adipogenesis 63 MMP2 63 mTOR signaling 63 5 HT2A receptor 63 LSD1 63 FSH receptor 63 glucagon receptor 63 proapoptotic 63 interferon γ 63 osteoclast activity 63 S1P 63 ERK phosphorylation 63 transmembrane protein 63 receptor tyrosine kinase 63 coexpression 63 calcineurin 63 Immunohistochemical analysis 63 Hh pathway 63 neurotrophic 63 cathepsins 63 c myb 63 oncoproteins 63 cyclic adenosine monophosphate cAMP 63 HDAC2 63 bFGF 63 Anticalin ® 63 EGFR signaling 63 constitutively expressed 63 autophagic 63 inhibitory effects 63 secretase 63 miRNA expression 63 tumor suppressor protein 63 TGF beta pathway 63 eotaxin 63 RRM1 63 synthetase 63 Fas ligand 63 TLR2 63 exocytosis 63 arginase 63 ligand binding 63 stem cell pluripotency 63 5 hydroxymethylcytosine 63 MMP9 63 trans splicing 63 CDK4 63 siRNA therapeutics 63 CCR9 63 gene silencing 63 TLR9 63 HIF 1α 63 tropomyosin 63 PDGF B 63 FKBP# 63 extracellular signal 63 post transcriptional 63 Phosphorylation 63 short interfering RNA 63 galectin 63 Tubulin 63 somatostatin 63 HepG2 cells 63 inflammatory cytokine 63 Skp2 63 microRNA molecule 63 PI3K/mTOR 63 NFkappaB 63 CCR3 63 CCL# 63 NFκB 63 pathophysiological effects 63 WT1 63 LRP6 63 metabolic enzymes 63 adenylate cyclase 63 cell adhesion molecule 63 BRAF kinase 63 Inhibition 63 antiangiogenic 63 muscarinic receptor 63 V#F mutation 63 mitochondrial respiration 63 nAChRs 63 synaptogenesis 63 JAK3 63 isoenzymes 63 guanosine 63 dimerization 63 immune modulatory 63 HBx 63 E3 ligase 63 glycosyltransferase 63 ERa 63 VEGFR1 63 TIMP 1 63 bispecific 63 Integrin 63 effector functions 63 adrenoceptor 63 TrkA 63 eIF2 63 cytostatic 63 alpha subunit 63 immunological responses 63 small molecule tyrosine 63 CCX# 63 IL #p# 63 cytosolic 63 promoter methylation 63 effector cells 63 inducible 63 neuronal differentiation 63 endothelial nitric oxide synthase 63 isotypes 63 H#K#me# 63 ERK2 63 IRE1 63 5 HT2A serotonin 63 peroxisome proliferator activated 63 sd rxRNA 63 caveolin 63 USP# 63 cyclins 63 #S proteasome 63 gene encoding 63 metalloprotease 63 interferon IFN 63 matrix metalloproteinase 63 adenoviral 63 MAPKs 63 P#Y# [002] 63 CK2 63 effector molecules 63 osteogenic 63 TGF b 63 homologous recombination 63 prostanoid 63 thrombopoietin 63 MAPK signaling pathway 63 Factor Receptor 63 EGFR receptor 63 Foxp3 63 SMAD4 63 humoral immune responses 63 IGFBP2 63 CCR2 63 nicotinic receptor 63 vanilloid receptor 63 Signal transduction 63 mutational status 62 cyclin dependent kinases CDKs 62 costimulatory molecules 62 GSOs 62 RUNX3 62 NLRP3 62 Cre recombinase 62 #beta HSD 1 62 cAMP 62 endoglin 62 CD8 T cell 62 transdifferentiation 62 glucan 62 NF kB pathway 62 ERK1 62 ERK5 62 hepatocyte 62 receptor kinase 62 smooth muscle myosin 62 Xanafide 62 demethylation 62 epithelial mesenchymal transition 62 GLUT1 62 factor HGF 62 NO synthase 62 BMP signaling 62 viral proteins 62 apoE 62 induces apoptosis 62 LPS induced 62 p# alpha [001] 62 adaptive immunity 62 Th2 cytokines 62 CPEB 62 GAPDH 62 peptidomimetic 62 small interfering RNA 62 osteogenic differentiation 62 acetylcholinesterase AChE 62 murine 62 cyclin dependent kinase inhibitor 62 Rac1 62 CGRP 62 phosphate S1P 62 XBP1 62 AMACR 62 granzyme B 62 upregulation 62 A3 adenosine receptor 62 EZN 62 PDE1 62 immunostimulatory effects 62 potent inhibitors 62 uricase 62 PPARγ 62 osteoblast differentiation 62 TGF beta signaling 62 IFN α 62 apoptotic 62 transcriptionally 62 cyclin dependent kinase 62 cytoplasmic domain 62 N Myc 62 BCL2 62 potently inhibit 62 TRPV4 62 cystic fibrosis transmembrane 62 Wnt signaling pathway 62 TRPV3 62 TLR8 62 P selectin 62 endonuclease 62 Sgk1 62 homodimers 62 NKT cells 62 Kinases 62 HDACs 62 mGluR5 antagonist 62 lytic 62 ERK signaling 62 vascular endothelial cells 62 IGF1R 62 acetylation 62 coagulation cascade 62 mTOR signaling pathway 62 Drp1 62 astrocytic 62 SOCS3 62 cyclic AMP cAMP 62 humanized monoclonal antibodies 62 tau phosphorylation 62 constitutively 62 prostate epithelial cells 62 Hh 62 TORC2 62 selective agonist 62 proteolytic 62 cyclin E 62 paxillin 62 endogenous ligand 62 PPARgamma 62 tumor suppressive 62 cellular senescence 62 Secretase 62 ligases 62 E cadherin expression 62 BCL6 62 FGF2 62 #HT#A 62 EZH2 62 monomeric 62 xenograft models 62 CHO cells 62 sphingolipid 62 #T# L1 62 hnRNP 62 muscarinic receptors 62 transferase 62 Vidofludimus 62 c Myb 62 RAF kinase 62 XmAb# 62 alpha#beta# integrin 62 mitotic progression 62 IL #E 62 transduce 62 prolyl 62 GRP# 62 aldose reductase 62 PI3K 62 norepinephrine reuptake inhibition 62 siRNA 62 decarboxylase 62 intracellular uptake 62 deacetylase 62 rxRNA 62 CXCL# 62 DHFR 62 HSP# 62 endogenous ligands 62 substrate specificity 62 homeobox gene 62 RKIP 62 oncogenic transformation 62 potent inhibitor 62 glycogen synthase kinase 62 C5a 62 phosphorylates 62 PTP1B 62 p# inhibitor 62 CXCR4 62 PC# cells 62 tumor vasculature 62 aberrantly activated 62 guanylate cyclase 62 Chemokine Receptor 62 tRNA synthetase 62 hydrolase 62 Th1 type 62 caveolin 1 62 keratinocyte 62 BMP4 62 UCOE 62 tyrosine kinase receptor 62 secretory pathway 62 MDM2 62 siRNAs targeting 62 TNF receptors 62 c Abl 62 oncogenic signaling 62 p# MAP kinase 62 cardiomyocyte 62 HGF c Met 62 neuronal nitric oxide synthase 62 FOXO3a 62 RNAi pathway 62 glioma cells 62 selective modulator 62 cell lysis 62 beta actin 62 IGF IR 62 partial agonists 62 immunomodulatory effects 62 LPA1 receptor 62 cystic fibrosis transmembrane conductance 62 5 HT2C receptor 62 ubiquitin ligases 62 FAAH 62 dihydrofolate reductase 62 STAT5 62 pertussis toxin 62 monocyte 62 DNA intercalator 62 glucocorticoid receptors 62 Smad3 62 Oncogenic 62 Rap1 62 EGF receptors 62 Runx2 61 ZFN 61 cytolytic 61 innate immune responses 61 PI3K inhibitor 61 pleiotropy 61 heterodimers 61 beta amyloid peptide 61 antitumoral 61 nAChR 61 anti proliferative 61 HMG CoA reductase 61 siRNAs 61 poly ADP ribose polymerase 61 overexpressing 61 phagocyte 61 PIK3CA 61 transduction 61 hedgehog pathway 61 liposomal formulation 61 mineralocorticoid receptor 61 mutagenesis 61 interleukin IL 61 microtubule dynamics 61 TLR3 61 tyrosine hydroxylase 61 adrenergic receptors 61 FGFR2 61 neurotrophin 61 beta globin gene 61 inducible nitric oxide synthase 61 ACh 61 intracellular 61 HGS ETR2 61 agonism 61 humanized antibody 61 FGFR1 61 cortisol receptor 61 protein biosynthesis 61 amyloidogenic 61 urate oxidase 61 oligomerization 61 Integrins 61 estrogen receptor alpha 61 nucleolin 61 ornithine decarboxylase 61 pharmacological inhibition 61 fusion protein 61 immune modulation 61 5HT 61 kinase pathway 61 heterologous expression 61 ADAMTS# 61 chaperone proteins 61 immunofluorescence staining 61 osteoblast 61 evolutionarily conserved 61 immunogens 61 PIP3 61 #ß 61 pharmacodynamic PD 61 Survivin 61 siRNA binds 61 ABCA1 61 heterologous 61 Chinese Hamster Ovary 61 small molecule inhibitors 61 PTHrP 61 Epidermal Growth Factor Receptor 61 Pentraxin 2 61 FGFR4 61 hepatoma 61 cytotoxic T lymphocyte 61 preclinically 61 MDSCs 61 dephosphorylation 61 selectively inhibits 61 selective agonists 61 HSP# inhibitor 61 PI3K pathway 61 BACE1 61 apoptosis proteins 61 PGE2 61 interleukin IL -# 61 GABAB receptors 61 Wnt pathway 61 peptide antigens 61 protein kinase C 61 thymidine 61 gamma secretase 61 Activating mutations 61 mediated phosphorylation 61 siRNA sequences 61 cells transfected 61 tolerogenic 61 nucleosides 61 IMPDH 61 potent inducer 61 protein tyrosine phosphatase 61 mitogenic 61 #ME# 61 cMET 61 thrombospondin 61 MAPK 61 eIF 4E 61 serotonin reuptake 61 IGFBP 3 61 vascular endothelial 61 gene rearrangements 61 nucleolar dominance 61 NFAT 61 physiologically relevant 61 co stimulatory molecules 61 Hcrt 61 humoral responses 61 APOBEC3G 61 PI3 kinase 61 ZFP transcription factors 61 receptor activation 61 glutamate receptors 61 mitogen activated protein kinases 61 adhesion molecule 61 Sertoli cell 61 cytochrome P# 61 XL# inhibits 61 Preclinical studies suggest 61 plasminogen 61 allosteric 61 AhR 61 activating mutations 61 GSK 3ß 61 PI3K/AKT 61 Î ² 61 molecularly targeted 61 PKC alpha 61 mRNA expression 61 ER alpha 61 proteoglycan 61 colony stimulating factor 61 TGFß 61 c myc gene 61 Anticalins R 61 FOXP3 61 morphogen 61 EF Tu 61 alpha7 61 NK1R 61 galectins 61 cytokine receptor 61 HDAC enzymes 61 protein kinases 61 E3 ubiquitin ligase 61 cellular prion protein 61 selective antagonist 61 EGFR pathway 61 hENT1 61 mRNA translation 61 Bcr Abl 61 Monocytes 61 circadian clock genes 61 sd rxRNA compounds 61 downregulating 61 JAK2 enzyme 61 aberrant activation 61 H#K# [002] 61 receptor signaling 61 4E BP1 61 β1 61 STAT3 signaling 61 NADPH oxidase 61 inhibitory 61 small molecule defensin 61 thrombin receptor 61 neurturin 61 mTORC1 61 NS5B polymerase 61 ErbB receptors 61 putative biomarkers 61 endosomal release 61 CD#c 61 neurotrophic factor 61 induced apoptosis 61 humanized monoclonal 61 Enkephalin 61 NPD1 61 Vpu 61 anti angiogenic drugs 61 potent cytotoxic 61 siRNA molecules 61 adenoviral vectors 61 miRNAs 61 fast skeletal troponin 61 monocytes macrophages 61 Arp2 3 61 transmembrane receptor 61 CTLA 4 61 Treg cell 61 X inactivation 61 intracellular pathway 61 utrophin 61 hydroxylation 61 phosphoinositide 61 CD# ligand 61 viral kinetics 61 synaptic transmission 61 CXCL5 61 PAR1 61 IFN alpha 61 Transcriptional 61 chromosome condensation 61 Androgen Receptor 61 Signaling Pathway 61 lymphangiogenesis 61 nutlin 61 Fibroblast Growth Factor Receptor 61 small molecule inhibitor 61 Cytotoxic T 61 LRRK2 61 methyl D aspartate 61 humoral antibody 61 MicroRNA 61 CD# antibody [001] 61 FGF receptor 61 granzyme 61 EphA2 61 RNA polymerases 61 kinase domain 61 erythropoiesis 61 small molecule activators 61 Caspase 61 IFN ß 61 Overexpression 61 MAb 61 cdk5 61 glycosylation 61 Tumor Necrosis Factor 61 polyamine 61 VEGFR2 61 PPAR gamma 61 SIRT1 enzyme 61 fatty acid synthase 61 JAK inhibitors 61 acetyltransferase 61 PAK1 61 RANKL 61 molecular mimicry 61 annexin V 61 downstream effector 61 LDL receptor 61 immunodominant 61 Microtubule 61 polypeptides 61 peroxisomes 61 antisense inhibitors 61 5alpha reductase 61 modulatory 61 beta arrestin 61 mTOR 61 glycolipids 61 immunoprecipitation 61 biogenesis 61 bispecific antibody 61 thymic 61 geldanamycin 61 lentiviral 61 5 HT2A 61 Topoisomerase II 61 prodrugs 61 neutralizing antibody 61 CENP E 61 PAX5 61 chemoresistance 61 virus AAV 61 subcellular compartments 61 histone deacetylases HDACs 61 Factor VEGF 61 orally bioavailable 61 Protein Kinase 61 catalytic subunit 61 PI3K delta 61 luciferase reporter 61 tumor necrosis 61 MDR1 61 postsynaptic 61 dopamine transporter 61 Aurora kinases 61 caspase activation 61 mediated apoptosis 61 aT cell 61 effector T 61 autocrine 61 aP2 61 LKB1 61 cyclooxygenase COX 61 NS#/#A protease 61 coreceptor 61 CaM 61 FBPase 61 acinar 61 replicase 61 p# pathway 61 activate p# 61 Spiegelmer ® 61 tubulin 61 NF KB 61 enzyme inhibitors 61 VCAM 1 61 LEX System 61 #beta HSD1 61 GABAergic 61 PGC 1alpha 60 MET amplification 60 hapten 60 inhibit viral replication 60 cytokine receptors 60 receptor molecule 60 humoral immunity 60 histone deacetylation 60 CellPort Technologies 60 nNOS 60 mTOR inhibitors 60 subcellular localization 60 membrane receptors 60 nitric oxide synthase 60 vesicle fusion 60 RIP1 60 immunoblot 60 anti apoptotic 60 effector memory 60 CDK8 60 cytidine 60 TXNIP 60 partial agonist 60 palytoxin 60 messenger ribonucleic acid 60 pro apoptotic 60 selective inhibitors 60 synthetic siRNAs 60 clusterin 60 SUMOylation 60 annexin 60 monoclonal antibody mAb 60 recombinant protein 60 meiotic recombination 60 serotonin receptor 60 Hsp# chaperone 60 ErbB4