Related by context. All words. (Click for frequent words.) 68 FGFs 67 CB2 receptor 67 neurite outgrowth 66 cellular pathways 66 p# activation 66 Treg cell 65 cytoprotective 65 synovial cells 65 primary cilia 65 PHD2 65 anti angiogenic drugs 64 cathepsin K 64 metabolizing enzymes 64 neuroinflammation 64 Smac mimetic 64 LRP5 64 pleiotropic effects 64 neuron degeneration 64 underlying molecular mechanisms 63 EBV infection 63 HCV replication 63 fibrotic disease 63 Smac mimic 63 RNA silencing 63 selective inhibition 63 amyloid plaque formation 63 immunological responses 63 molecular underpinnings 63 histone deacetylases 63 mtDNA mutations 63 Notch receptors 63 inhibitory neurotransmitters 63 intracellular signal transduction 63 splice variants 63 epithelial tissues 63 serotonin synthesis 63 cholesterol homeostasis 63 potent inhibitors 63 ERK signaling 63 ACAT2 63 pleiotropic 63 telomerase inhibition 63 neuro protective 63 PPARγ 63 cell signaling pathways 63 Misfolded proteins 62 plasma kallikrein 62 protein tyrosine phosphatases 62 stem cell pluripotency 62 ADME properties 62 BRAF kinase 62 epigenetic mechanisms 62 #beta HSD1 62 tumorigenicity 62 enzymatic pathways 62 RKIP 62 FUS1 62 chemosensitivity 62 mammary cells 62 MetAP2 62 biologic pathways 62 FMRP protein 62 prostaglandin synthesis 62 sphingolipid 62 non coding RNA 62 axonal degeneration 62 metabolic enzymes 62 environmental toxicants 62 iPS derived 62 STAT3 signaling 62 spermidine 62 tryptase 62 inhibit angiogenesis 62 ADAMTS# 62 immune modulatory 62 UCP2 62 SGK1 62 tumor vascularization 62 immunoregulatory 62 CCR3 62 neuronal dysfunction 62 antibody mediated 62 Wnt signaling pathway 62 immune modulating 62 antiviral cytokines 62 FGF2 62 PDE#A 62 MEK inhibitors 62 pharmacodynamic parameters 62 pRb 62 γ secretase 62 oncomodulin 62 neurotrophic 61 fusion enhancers 61 beta adrenergic receptors 61 innate immune responses 61 galanin 61 HER2 expression 61 autophagic 61 immunomodulatory effects 61 p# mutations 61 serum biomarkers 61 DNMT1 61 synaptogenesis 61 epithelial barrier 61 antiapoptotic 61 anti CD3 61 protein misfolding diseases 61 chemical reactivity 61 abnormal proteins 61 phenotypic expression 61 molecular biomarkers 61 PECAM 1 61 microtubule dynamics 61 biologic pathway 61 PKM2 61 pathophysiological mechanisms 61 cytochromes P# 61 druggable target 61 activate p# 61 Th2 cytokines 61 proton pump 61 inhibiting enzymes 61 VEGF inhibitors 61 BubR1 61 chromosomal instability 61 PPAR gamma 61 Neuropeptide Y 61 PPARg 61 receptor subtypes 61 immune modulator 61 amyloid formation 61 progranulin 61 antitumour 61 impair fertility 61 underlying pathophysiology 61 neuropsychiatric diseases 61 glial tumors 61 glucocorticoid receptors 61 BChE 61 cathepsins 61 antimetastatic 61 subcellular compartments 61 mutant proteins 61 cultured mammalian cells 61 infectious prion proteins 61 epigenetic regulation 61 prodynorphin 61 chromosomal rearrangement 61 Hh pathway 61 endogenous ligands 61 SIRT3 61 TRIM5a 61 prostanoid 61 isotypes 61 TMEM#B 61 protein kinase C 61 overactivation 61 Nedd4 61 GPI anchored 61 antiangiogenesis 60 anticancer activity 60 pathophysiological effects 60 apoE 60 inhibiting telomerase 60 Hsp# [001] 60 neuronal synapses 60 proliferative disorders 60 androgen signaling 60 stathmin 60 Angiotensin converting enzyme 60 Helicobacter 60 DGAT1 60 adhesion proteins 60 molecular determinants 60 K ras mutations 60 neurobiological mechanisms 60 cMET 60 serotonin transporters 60 Oxidative damage 60 Fibroblast Growth Factor Receptor 60 oncogenic transformation 60 TRP channels 60 COX enzymes 60 GRP# 60 HCV protease inhibitors 60 tissue homeostasis 60 prostaglandin D2 60 amyloid deposition 60 activated microglia 60 neurotransmitter receptor 60 TPMT 60 endogenous cannabinoids 60 cellular metabolism 60 extracellular dopamine 60 senescent cells 60 fatty acid synthase 60 intestinal epithelium 60 epigenetic modifications 60 bioactive molecules 60 SMAD4 60 Darapladib 60 excitotoxic 60 humoral responses 60 4E BP1 60 EGFR pathway 60 siRNA therapeutics 60 IKK2 60 mechanistic insights 60 sarcosine 60 hematopoietic cells 60 dihydrofolate reductase 60 motor neuron degeneration 60 DNA methylation patterns 60 CCR1 60 DNA demethylation 60 fatty acid biosynthesis 60 tumor suppressor protein 60 mTOR inhibition 60 immuno modulatory 60 M.tb 60 Clusterin 60 herpesviruses 60 neurotransmitter GABA 60 SIRT1 activators 60 elastase 60 ABCA1 60 SH2 B 60 methyltransferases 60 Notch signaling 60 mTORC1 60 LIS1 60 cyclic adenosine monophosphate cAMP 60 colon carcinogenesis 60 sGC 60 growth hormone secretion 60 breast cancer metastasis 60 humanized monoclonal antibodies 60 oxidized lipids 60 eTag assays 60 multiplex assay 60 podocyte 60 PI3K signaling 60 Smad7 60 epigenetic alterations 60 kidney urologic 60 Rh proteins 60 CMV infections 60 secretory pathway 60 cyclic AMP cAMP 60 NKX#.# 60 eotaxin 60 mutant huntingtin protein 60 flavopiridol 60 glycolipids 60 transthyretin 60 intercellular signaling 60 fatty acid metabolism 60 microglial 60 immunostimulatory effects 60 mitochondrial metabolism 60 commensal bacteria 60 mutated K ras 60 biochemical abnormalities 60 anti angiogenic therapies 60 IFN γ 60 pharmacodynamic markers 60 synapse formation 60 matrix metalloproteinases 60 sortilin 60 DNA gyrase 60 Anticalins ® 60 tyrosine phosphorylation 60 ADDL 60 NF kB pathway 60 xenobiotic 60 PPAR γ 60 synthetic lethality 60 glucocorticoid hormones 60 mitochondrial fusion 60 receptor inhibitor 60 TGF ß1 60 Cathepsin B 60 Ets2 60 PKCi 60 GCN2 60 glutamate receptors 60 immunopathology 60 myelination disorders 60 Smac mimetics 60 telomerase inhibitor 60 mesenchymal cell 60 peroxisome 60 proteoglycan 60 proteosome 60 hepatic fibrosis 60 hyperactivation 60 PDGFR 60 furanones 60 bryostatin 60 mTOR inhibitors 60 drug metabolizing enzymes 59 histone modifications 59 glucocorticoid receptor 59 neuroactive 59 redox active 59 Smad3 59 potent neuroprotective 59 HIF 1α 59 MAP kinases 59 HER2 neu 59 methylation patterns 59 CEACAM1 59 retinoid X 59 mitochondrial DNA mutations 59 polyketides 59 treating neuropathic pain 59 TGF beta pathway 59 epigenetic inheritance 59 keratinocyte 59 bone metabolism 59 mevalonate 59 nitric oxide synthase 59 genomic alterations 59 tRNA synthetases 59 GSK3B 59 FTIs 59 Nanobacteria 59 epigenetic markers 59 lung fibroblasts 59 coactivators 59 signaling cascades 59 immunomodulation 59 HDACs 59 endoglin 59 selectively inhibited 59 PTPN# 59 SIRT2 59 antitumoral 59 immunological mechanisms 59 c Abl 59 myeloproliferative diseases 59 CRAC channel 59 anionic backbone 59 transcriptional machinery 59 anti neoplastic 59 insulin sensitizing 59 SIRT1 gene 59 PARP inhibition 59 cAMP signaling 59 eukaryotic cell 59 synthetic analogues 59 protein alpha synuclein 59 TGF beta signaling 59 ERK1 2 59 chimeric mice 59 rBChE 59 aneuploid cells 59 stimulate neurogenesis 59 micro RNAs 59 eicosanoids 59 β amyloid 59 intracellular pathways 59 c myc gene 59 vitamin D receptors 59 c MYC 59 GAGs 59 cPLA2 59 enzyme cofactor 59 act synergistically 59 hypoxia inducible factor 59 tumor hypoxia 59 heparanase 59 molecular abnormalities 59 ubiquitylation 59 Genetic variants 59 neuronal plasticity 59 stimulates angiogenesis 59 connexin 59 beta defensins 59 EGFR tyrosine kinase inhibitors 59 micronuclei 59 Wnt1 59 Genetic predisposition 59 antiplatelet therapies 59 hyperactivated 59 EP1 receptor 59 glycolytic 59 #ME# 59 SCD1 59 carbohydrate polymers 59 alpha#beta# integrin 59 siRNA knockdown 59 S6K 59 A3 adenosine receptor 59 GABAB receptors 59 gastrointestinal stromal tumors GISTs 59 modifier genes 59 axonal regeneration 59 telomere maintenance 59 chemoprotective 59 TAT2 59 RIP1 59 virulence genes 59 coagulation cascade 59 Kv#.# 59 chronic viral infections 59 teratogens 59 GABAA receptors 59 oncogenesis 59 CD# expression [001] 59 erythropoietic 59 eicosanoid 59 atherogenesis 59 β catenin 59 genetic determinants 59 genes encode proteins 59 amyloid peptide 59 p# alpha [001] 59 oncoproteins 59 favorable pharmacokinetic 59 antitumor efficacy 59 CDK4 59 transgene expression 59 neuronal function 59 RBP4 59 outer membrane proteins 59 Akt1 59 oxidases 59 divide uncontrollably 59 protein tyrosine phosphatase 1B 59 lipid synthesis 59 gamma secretase inhibitor 59 intracellular bacteria 59 adiponectin levels 59 potently inhibit 59 neurofibromin 59 Cyclin E 59 BDNF protein 59 cytokine receptor 59 mitochondrial respiration 59 NEDD9 59 osteopontin 59 viral proteins 59 osteoprotegerin 59 cytostatic 59 EGFR protein 59 OGG1 59 spontaneous mutations 59 effector function 59 intracellular pathogens 59 lysosomal 59 protein homeostasis 59 ACh 59 unmeasured factors 59 GnT 4a 59 biochemical mechanisms 59 norepinephrine reuptake inhibition 59 ERK pathway 59 PGE2 59 DNA methyltransferases 59 NKT cells 59 telomerase activity 59 telomere dysfunction 59 GLUT4 59 acetylcholine receptor 59 amyloid deposits 59 clonogenic 59 immunomodulatory 59 TRAIL induced apoptosis 59 neural crest stem cells 59 overactivated 59 apoptosis pathway 59 regulate gene expression 59 radiosensitivity 59 epigenetically 59 ubiquitin ligases 59 VDAs 59 PDGF alpha receptor 59 oxidant stress 59 cardiotoxic 59 partial agonists 58 biomarker assay 58 differential gene expression 58 activate AMPK 58 cisplatin resistant 58 vivo RNAi 58 TGF alpha 58 proteolysis 58 superoxide anion 58 plasminogen 58 inhibiting COX 58 ARF1 58 endoplasmic reticulum stress 58 mechanistic studies 58 ADAM# 58 amyloidogenic 58 polyamines 58 JAK2 enzyme 58 podocytes 58 nerve degeneration 58 enzymatic pathway 58 deacetylase inhibitors 58 antitumor effect 58 potent cytotoxic 58 Hedgehog signaling 58 ADDLs 58 mitochondrial toxicity 58 dopamine transporter 58 phagocytic cells 58 bicyclic 58 chromosomal mutations 58 RRM1 58 rifamycins 58 membrane permeability 58 Wnt proteins 58 hepatic stellate cells 58 immunotoxins 58 MAPK pathway 58 pathogenic mechanisms 58 Shp2 58 p#INK#a 58 NF kB signaling 58 CD# expression [002] 58 MT1 MMP 58 osteoclast activity 58 JAK3 58 RNAi mediated 58 lung epithelium 58 MTP inhibitor 58 defensin mimetic antibiotic 58 #T# L1 58 NSCLC tumors 58 adenosine receptor 58 Genetic variations 58 SOD1 gene 58 inverse agonist 58 neuro degenerative diseases 58 physicochemical properties 58 Polycomb proteins 58 PCA3 gene 58 TGF β 58 LTB4 58 granzyme B 58 transcriptional regulation 58 synaptic function 58 prostate carcinogenesis 58 Fas ligand 58 Leydig cells 58 E#F# 58 antagomirs 58 Amyloid plaques 58 prion infections 58 HMG CoA reductase 58 TLR8 58 serine proteases 58 survivin expression 58 oxysterols 58 Glucocorticoids 58 cytolytic 58 mitogenic 58 intercellular communication 58 aberrant activation 58 isoenzymes 58 GSK3 58 acetylcholinesterase 58 lymphatic vasculature 58 EAAT2 58 carbohydrate metabolism 58 selectively modulating 58 Caspases 58 butyrylcholinesterase 58 Dr. Bezprozvanny 58 amyloid beta plaques 58 vWF 58 EGF receptors 58 preferentially bind 58 thioredoxin 58 telomerase activation 58 AEG# 58 TNFa 58 VEGFb 58 induce apoptosis 58 NFκB 58 CCL# 58 prion strains 58 inhibit enzymes 58 peptide antigens 58 NOD2 58 adult neurogenesis 58 von Willebrand 58 fusogen 58 beta1 integrin 58 microRNA miR 58 FSH receptor 58 Protein Kinase C 58 HDAC inhibition 58 vivo potency 58 chitinase 58 experimentally induced 58 allergic inflammation 58 APOBEC3G 58 nutlin 3a 58 metalloprotease 58 HER2 overexpression 58 pro angiogenic 58 neuronal nicotinic receptors NNRs 58 Inflammatory diseases 58 myopathies 58 CYP #A# 58 glial derived neurotrophic 58 anticancer therapeutics 58 CaR 58 epigenetic changes 58 Symadex 58 PGC 1α 58 fluid shear 58 uPAR 58 posttranslational modifications 58 GABA receptor 58 inhibit viral replication 58 proliferative diseases 58 Ab# 58 mGluR5 antagonist 58 TLR antagonists 58 protein biosynthesis 58 toxic beta amyloid 58 nicotinic acetylcholine receptor 58 mucins 58 STIM1 58 tumor necrosis 58 vimentin 58 nAChR 58 Alu RNA 58 microglial activation 58 neurotrophic factors 58 tumor subtypes 58 inducible nitric oxide synthase 58 electrophysiologic 58 Epstein Barr virus EBV 58 misfolded protein 58 microRNA molecules 58 TGF b 58 genotoxic stress 58 CIB1 58 SETDB1 58 NF KB 58 prostate epithelial cells 58 axon guidance 58 pharmacokinetic interactions 58 enzymatically active 58 JAK2 mutation 58 Hfq 58 Wnt#b 58 calcineurin 58 epigenetic silencing 58 Genetic variation 58 shiga toxin 58 anti secretory 58 MEK ERK 58 HSP# 58 Autoimmune diseases 58 kallikrein 58 neuroligins 58 NPM1 mutation 58 chlamydial 58 triterpenoids 58 alpha synuclein protein 58 thymidylate synthase 58 TXNIP 58 hedgehog signaling 58 CaM kinase II 58 protein albumin 58 MAPCs 58 calpain 58 hypermethylated 58 clusterin 58 α synuclein 58 somatostatin 58 previously uncharacterized 58 GPR# [002] 58 preclinically 58 miR #a [001] 58 aldosterone hormone 58 gastric carcinomas 58 antisense inhibitors 58 cardiac contractility 58 largazole 58 VIPR2 58 neuronal signaling 58 botulinum neurotoxins 58 pancreatic endocrine 58 amyloid protein plaques 58 ENMD # 58 Histone deacetylase 58 Eg5 58 #ß HSD1 58 inhibitory effects 58 GPx 58 HbF 58 ubiquinol 58 PTEN gene 58 neurotransmitter glutamate 58 JAK#/JAK# 58 Dr. Rafii 58 kinase inhibition 58 enzyme inhibitors 58 folate metabolism 58 biotransformation 58 substrate specificity 58 causative genes 58 Tß4 58 vascular disrupting 58 CXCR7 58 pyrimidines 58 microvessels 58 hedgehog pathway 58 nanohorns 57 EphA2 57 melanocortin receptors 57 NMDA antagonists 57 physiologic mechanisms 57 PTEN mutations 57 p# inhibitors 57 metabolic alterations 57 phenotypic differences 57 biphosphonates 57 beta amyloid peptide 57 habenula 57 EGF receptor 57 NF kappaB pathway 57 rhinovirus infection 57 p#NTR 57 membrane fusion 57 non nucleoside 57 miR #a [002] 57 Imprinted genes 57 PhG alpha 1 57 CoVal TM fusion 57 LXRs 57 biologic therapeutics 57 pressure natriuresis 57 glucose homeostasis 57 diabetic microvascular complications 57 AT1R 57 MAP kinase 57 adeno associated viruses 57 astrocyte cells 57 inhibit metastasis 57 hippocampal cells 57 racemic mixture 57 Skp2 57 druggable targets 57 Aviptadil 57 PTP 1B 57 Abeta# 57 isoenzyme 57 PI3K/mTOR 57 TGF ß 57 binding affinities 57 glioma cells 57 diabetic kidney 57 cells MSCs 57 fibrin deposition 57 fluorescent quantum dots 57 cyclic guanosine monophosphate 57 SOD1 57 LRP6 57 mGluR2 NAM 57 Micro RNAs 57 #BP# 57 forskolin 57 HuR 57 aldose reductase 57 tumor suppressor proteins 57 M. pneumoniae 57 potent stimulator 57 Stat5 57 intestinal mucosal 57 MAO B 57 NQO1 57 myo inositol 57 hydrophobicity 57 genetic manipulations 57 lung fibrosis 57 NPY expression 57 inherited mutations 57 short hairpin RNAs 57 protein misfolding 57 CaM kinase 57 apoptosis inducing 57 Skeletal muscle 57 transcriptional activity 57 replicative 57 Jhdm2a 57 antiangiogenic 57 NF κB 57 HepG2 cells 57 cyclophilin D 57 FKBP# 57 AMPK activation 57 circadian genes 57 TRPV1 receptors 57 NKT cell 57 TNFalpha 57 PDGF receptor 57 Aâ 57 HDAC6 57 intracellular pH 57 ß amyloid 57 protein tyrosine phosphatase 57 antiresorptive 57 acadesine 57 mutated protein 57 leukaemic stem cells 57 sphingolipids 57 intracellular proteins 57 CHD5 57 Cyclin D1 57 virulence determinants 57 stem cell differentiation 57 Genetic mutations 57 DHFR 57 galectins 57 microvascular endothelial cells 57 microglial cells 57 alpha synuclein gene 57 genotoxicity 57 immunotoxin 57 Endocannabinoids 57 gamete formation 57 leukocyte recruitment 57 anticancer therapy 57 Nanobodies ® 57 suppresses tumor 57 Akt activation 57 mitochondrial function 57 systemic toxicity 57 biogenesis 57 homeostatic mechanism 57 p tau 57 mitochondrial proteins 57 humoral immunity 57 urease 57 C. pneumoniae 57 E. faecalis 57 organ transplant rejection 57 potentiation 57 physico chemical properties 57 CCL5 57 CD#L 57 peroxisomes 57 Stress hormones 57 hypericin 57 physiological mechanisms 57 oxidative stress markers 57 biodistribution 57 fatty acid oxidation 57 amygdala neurons 57 PIK3CA 57 myeloperoxidase 57 PI3 kinase inhibitors 57 cholecystokinin CCK 57 effector functions 57 peroxisomal 57 nonclinical studies 57 monogenic 57 potent inducer 57 transcriptional repressor 57 BRAF gene 57 neuropilin 57 protein synthesis machinery 57 immuno inflammatory 57 thyrotropin 57 bacterial enzyme 57 γδ T cells 57 gene amplification 57 muscle contractility 57 SGS# 57 histone deacetylase HDAC 57 mRNA molecules 57 neurofibrillary 57 SSc 57 phosphate S1P 57 therapeutic monoclonal antibody 57 amyloid proteins 57 receptor subtype 57 PIP3 57 lymphomas leukemias 57 gliosis 57 cholesterol metabolism 57 apoptosis induced 57 phenotypic variability 57 Antifreeze proteins 57 beta Estradiol 57 deacetylation 57 lymphotoxin 57 downregulate 57 tubulin binding 57 GPR# receptor [002] 57 AQD class 57 renal fibrosis 57 mimetics 57 immune dysregulation 57 Thyroid hormones 57 GSOs 57 cholinergic neurons 57 NKG2D 57 xanthine 57 chloride channels 57 CDK inhibitor 57 CYT# potent vascular disrupting 57 p# pathway 57 apoptotic pathway 57 specific lectin receptors 57 xenobiotics 57 nephrogenic 57 therapeutically useful 57 peroxidation 57 intracellular uptake 57 antiangiogenic agents 57 subtype selective 57 Prof. Krainer 57 intestinal mucosa 57 hERG 57 adipogenic 57 neuro endocrine 57 metalloproteins 57 BCR ABL mutations 57 β1 57 AKT1 57 sd rxRNA 57 SFRP1 57 mitochondrial abnormalities 57 JAK inhibitors 57 Upregulation 57 modulate gene expression 57 oncogenic mutations 57 tipifarnib 57 dopamine D2 receptor 57 FANCD2 57 vascular endothelial 57 small molecule activators 57 histone deacetylase inhibitors 57 SUMOylation 57 glutamate signaling 57 kynurenic acid 57 imatinib Gleevec 57 adrenal hormones 57 mesothelin 57 SIRT1 activation 57 potent suppressor 57 receptor gamma 57 NEUGENE 57 antiproliferative effects 57 ncRNA 57 therapeutically relevant 57 E. histolytica 57 steroidogenic 57 Wnt pathway 57 metalloproteinases 57 RUNX3 57 VEGF expression 57 huntingtin protein 57 IgG antibodies 57 Epstein Barr Virus EBV 57 neuroprotective properties 57 MIF protein 57 tenascin C 57 mechanistic explanation 57 epigenetic modification 57 CYP#A# enzyme 57 GRNOPC1 contains 57 lipoprotein metabolism 57 peptides proteins 57 gastric carcinoma 57 neuroblastoma tumors 57 FGFR1 57 hippocampal function 57 osteolytic 57 macromolecular complexes 57 B7 H3 57 myelofibrosis polycythemia vera 57 mitogen activated protein kinases 57 Immunohistochemical analysis 57 mutant SOD1 57 p# mutation 57 morpholino 57 NFkappaB 57 integrin receptors 57 MMP# 57 nanomolar 57 coronary vasodilation 57 potent antiproliferative 57 Foxp3 57 pathogenic mutations 57 transgenic rats 57 opioid mediated 57 TIR1