Related by context. All words. (Click for frequent words.) 59 neuronal degeneration 58 Six3 58 CB2 receptor 57 ADAMTS# 57 underlying molecular mechanisms 57 synapse formation 57 neuronal dysfunction 57 epigenetic regulation 57 neuropsychiatric diseases 57 clefting 57 motor neuron degeneration 57 mGluR2 NAM 56 endocrine dysfunction 56 overactivation 56 neuropathologic 56 protein misfolding 56 synaptogenesis 56 hedgehog signaling pathway 56 renal fibrosis 56 nNOS 56 p# pathway 55 channelopathies 55 podocyte 55 neuronal plasticity 55 synaptic function 55 Ets2 55 Glucocorticoid 55 NF kB signaling 55 Skp2 54 causative genes 54 apoptotic pathway 54 oncogenesis 54 #beta HSD1 54 mitochondrial disorders 54 Dr. Bezprozvanny 54 promoter hypermethylation 54 hypothalamic pituitary adrenal axis 54 JAK2 enzyme 54 beta1 integrin 54 SIRT3 54 #ß HSD1 54 FGFs 54 tumor suppressor protein 54 epigenetic changes 54 neuroligins 54 adult neurogenesis 54 CHD7 54 p# activation 54 neuronal nitric oxide synthase 54 neural cells 54 γ secretase 54 pathogenic mechanisms 54 pharmacological chaperone 54 GPC5 54 amyloid protein plaques 54 Factor Receptor 54 neurotransmission 54 remyelination 54 mitochondrial dysfunction 53 synaptic plasticity 53 redox active 53 IDH mutations 53 genomic imprinting 53 polyamines 53 autocrine 53 NKX#.# 53 Wnt signaling pathway 53 oncomodulin 53 neurotrophic 53 BCL#A 53 Cathepsin B 53 KIBRA 53 peroxisomal 53 STAT3 signaling 53 kidney urologic 53 DISC1 53 monogenic 53 susceptibility gene 53 non coding RNA 53 Pten 53 lipoprotein metabolism 53 NOD2 53 RUNX3 53 neuronal differentiation 53 MAP kinases 53 transcriptional regulation 53 retinoid X 52 axonal degeneration 52 LKB1 52 neuropsychiatric disorder 52 pathophysiological effects 52 peroxisome 52 circadian clock genes 52 neurofibromin 52 epigenetic alterations 52 DNA methyltransferases 52 MEF2A 52 MECP2 gene 52 DNA methylation patterns 52 Wnt signaling 52 Induced pluripotent stem cells 52 Genetic variants 52 neuroinflammatory 52 ubiquitylation 52 LRP5 52 estrogen receptor alpha 52 FOXO1a 52 Stat5 52 DGAT1 52 Helicobacter 52 c Abl 52 Neuroprotection 52 COX enzymes 52 PAR1 52 dystrophin protein 52 microglial 52 Hutchinson Gilford progeria 52 IKK beta 52 ERK1 2 52 muscular dystrophies 52 Dysregulation 52 SH#B# 52 neural plasticity 52 Th1 type 52 prostate carcinogenesis 52 cdk5 52 protein dystrophin 52 PML RARA 52 tissue fibrosis 52 immunomodulatory effects 52 SCD1 52 siRNA knockdown 52 Decety 51 FGF2 51 Upregulation 51 NR2B 51 PTEN gene 51 neuromuscular junction 51 Epstein Barr Virus EBV 51 chromosome rearrangements 51 Angiotensin converting enzyme 51 Genetic variations 51 P#X# 51 neuro developmental 51 Smad3 51 genetic loci 51 NRG1 51 regulates gene expression 51 PPARγ 51 DEAR1 51 cAMP signaling 51 murine model 51 glucocorticoid receptor 51 hippocampal neurogenesis 51 GnT 4a 51 #q# deletion 51 IKK2 51 autophagic 51 autism susceptibility genes 51 histone methylation 51 LPA1 51 inosine 51 TGF b 51 EGFR signaling 51 telomere dysfunction 51 DLX5 51 transcriptional repression 51 neurogenesis 51 IRS1 51 copper zinc superoxide 51 epigenetic modification 51 aberrant activation 51 neurexins 51 fatty acid biosynthesis 51 tumorigenesis 51 antiproliferative effects 51 Li Fraumeni 51 IGFBP2 51 fatty acid metabolism 51 LRP6 51 p#INK#a 51 Hh pathway 51 Meckel Gruber 51 nicotinamide 51 histone acetylation 51 clonogenic 51 phosphorylates 51 heritable diseases 51 potent activator 51 transgenic mouse models 51 glutamatergic neurons 51 Cdk5 50 mitochondrial mutations 50 RNA silencing 50 Lrp5 50 microdeletion 50 p#NTR 50 calcium homeostasis 50 amyloid ß 50 neurite outgrowth 50 D aspartic acid 50 selective inhibition 50 neurobiological basis 50 PICALM 50 maturational 50 FGFR1 50 E3 ubiquitin ligase 50 Macrophage 50 PDGFR 50 VIPR2 50 Predisposition 50 cholesterol metabolism 50 INF2 50 Kv#.# 50 TMEM#B 50 inherited predisposition 50 small molecule activator 50 Neuronal 50 NK1R 50 glutamatergic 50 mutated K ras 50 amyloid plaque formation 50 TRAIL induced apoptosis 50 Neurogenesis 50 immunoregulation 50 urocortin 50 methylation markers 50 fatty acid synthase 50 cathepsins 50 Wnt#b 50 mitogen activated protein kinase 50 PRODH 50 FUS1 50 protein biosynthesis 50 synaptic transmission 50 fatty acid oxidation 50 ERK signaling 50 cell adhesion molecule 50 AT1R 50 experimental allergic encephalomyelitis 50 gastric carcinogenesis 50 Notch signaling 50 HDAC2 50 Li Fraumeni syndrome 50 ubiquitin ligase 50 FANCD2 50 p# MAPK 50 inherited mutations 50 cholesterol homeostasis 50 upregulates 50 alpha synuclein gene 50 microglial activation 50 STAT4 50 sGC 50 Inactivation 50 glutamate receptors 50 phosphatidylinositol 3 50 alpha synuclein protein 50 MAPK 50 phosphate S1P 50 nicotinic acetylcholine receptors 50 genomic alterations 50 chromatin remodeling 50 causative gene 50 induced neuronal 50 IRAK1 50 Myostatin 50 coding RNA 49 purinergic receptors P#X# 49 hypertension cardiovascular disease 49 Prox1 49 endophenotypes 49 LRP1 49 HIF 1α 49 MAPK pathway 49 unstable detrusor muscle 49 Kufs disease 49 mediated inhibition 49 protein misfolding diseases 49 neuropsychological deficits 49 GABA aminotransferase 49 metabonomics 49 FOXP3 49 prodynorphin 49 protein tyrosine phosphatase 1B 49 factor receptor FGFR 49 degenerative neurological diseases 49 dysregulated 49 chromatin remodeling complex 49 FGFR4 49 NMDA N 49 SMN protein 49 c Myb 49 synthetases 49 deacetylation 49 lipid homeostasis 49 CDH1 49 factor BDNF 49 intracellular protein 49 micro RNAs 49 hyperphosphorylation 49 brain derived neurotrophic 49 prostaglandin E2 49 pDCs 49 Cyclin D1 49 signaling cascades 49 cyclin E 49 CaM kinase II 49 Fibroblast Growth Factor Receptor 49 neurotrophic factors 49 molecular abnormalities 49 mda 7 49 TrkB 49 de novo mutations 49 GRP# 49 GABAergic interneurons 49 methyl D aspartate 49 neuropathological 49 c myc 49 PI3K signaling pathway 49 osteocalcin protein 49 IRF6 49 gene polymorphisms 49 pleiotropic 49 PON1 49 DNA hypermethylation 49 eotaxin 49 calpain 49 CNTNAP2 49 CTGF 49 mirror neuron system 49 Hedgehog signaling 49 Progressive Multifocal Leukoencephalopathy 49 DNA demethylation 49 palladin 49 gamma globin gene 49 LPA1 receptor 49 hypocretin neurons 49 SHANK3 49 Oncogenic 49 GPIHBP1 49 attention-deficit/hyperactivity 49 multisensory integration 49 calcineurin 49 chromosomal regions 49 hyperactivation 49 progressive neurodegenerative disorder 49 TSLP 49 potent inhibition 49 proinflammatory mediators 49 ApoE gene 49 Inhibitory 49 uricase 49 LPS induced 49 vascular endothelial 49 metalloproteinases 49 myo inositol 49 WDR# 49 downstream effector 49 noradrenergic 49 C EBP alpha 49 hippocampal function 49 Molecular Cancer 49 ErbB4 49 enkephalin 49 neuromotor 49 pRb 49 transmembrane receptor 49 gene locus 48 neuropsychological impairments 48 dysbindin gene 48 transgenic mouse model 48 lipid metabolism 48 TGFβ 48 myelination 48 protein kinase C 48 ERK5 48 FGFR2 48 sphingolipid 48 apoE 48 antibody mediated 48 Rb gene 48 Pin1 48 biobehavioral 48 mutant huntingtin protein 48 PDE5A 48 gastrin 48 SH2 B 48 muscle dystrophies 48 synthetase 48 #q#.# deletion syndrome 48 histone deacetylase 48 lysosomal 48 Sonic Hedgehog 48 cardiovascular disease osteoporosis 48 tRNA synthetase 48 ACh 48 MeCP2 protein 48 Spinal muscular atrophy 48 LRRK2 48 STK# [002] 48 BMP4 48 cystic fibrosis transmembrane conductance 48 destigmatizing 48 MeCP2 gene 48 cyclins 48 selectively inhibiting 48 Prenatal Alcohol 48 thyrotropin 48 hedgehog pathway 48 neuropsychiatric disorders 48 microRNA expression 48 stathmin 48 TSC1 48 CD#L 48 ERBB4 48 neurological impairments 48 apoE4 48 N myc 48 TXNIP 48 neurodevelopmental 48 heritable disorders 48 validate biomarkers 48 cortical excitability 48 MEK ERK 48 uPA 48 HDAC3 48 autism dyslexia 48 MTHFR 48 protein tyrosine phosphatase 48 mental retardation epilepsy 48 NMDA receptor 48 astrocytic 48 tyrosine phosphorylation 48 glucocorticoid receptor GR 48 peroxisome proliferator activated 48 Mouse Model 48 Lyn kinase 48 Hedgehog signaling pathway 48 c Src 48 progranulin mutations 48 RIP1 48 SOD1 48 validating biomarkers 48 BARD1 48 RRM1 48 pancreatic endocrine 48 signaling pathway 48 biomarker identification 48 DISC1 gene 48 serine threonine kinase 48 metabolomic profiling 48 Jhdm2a 48 cardiac fibroblasts 48 Wnt beta catenin 48 chemokine receptor 48 Aβ 48 mirror neuron 48 endogenous cannabinoid 48 immunotherapeutic approaches 48 extracellular signal 48 Micro RNAs 48 dopamine signaling 48 cyclooxygenase COX 48 calcium calmodulin dependent 48 GCN2 48 antiapoptotic 48 LRRK2 gene 48 S#K# 48 APOE genotype 48 neuroligin 48 gene MECP2 48 molecular biomarker 48 TGF β 48 Th# cells 48 SIRT1 activation 48 inflammasome 48 protein encoded 48 TERT 48 glutamate neurotransmitter 48 intracellular signaling 48 ankyrin B 48 Apolipoprotein E 48 p# mutations 48 genomic profiling 48 tumorigenicity 48 Nedd4 47 cyclo oxygenase 47 CEACAM1 47 PGC 1a 47 transcriptional silencing 47 Akt activation 47 ALDH2 47 mitochondrial DNA mtDNA 47 cortical plasticity 47 Signaling Pathway 47 HPA axis 47 Rb#/p# 47 observable traits 47 Epidermal Growth Factor Receptor 47 FoxO1 47 microtubule dynamics 47 mutant genes 47 BMP signaling 47 Epigenetic 47 PI3K Akt 47 amyloid toxicity 47 cMET 47 Monocyte 47 CYP#A# CYP#D# 47 LDLR 47 Celiac sprue 47 Cytochrome P# 47 c MET 47 microRNAs miRNAs 47 ERK pathway 47 CXCL# 47 TTR gene 47 mitogenic 47 Maven Semantic 47 mGluR4 activation 47 filaggrin 47 molecular mimicry 47 aneuploidies 47 opioid peptides 47 genetic susceptibility 47 Nkx#.# 47 COX2 47 vimentin 47 Froguel 47 HMG CoA reductase 47 preclinically 47 mouse neural stem 47 leptin signaling 47 ubiquitin ligases 47 epigenetic marks 47 cyclooxygenase 2 47 mTOR signaling 47 DNMT1 47 E selectin 47 Janus kinase 47 PPAR γ 47 hereditary breast 47 HER signaling pathway 47 UHCMC 47 AMPA receptor 47 induces apoptosis 47 neurobiological 47 chromosome translocations 47 CCR2 47 Id1 47 hereditary disorders 47 XMRV retrovirus 47 POMC neurons 47 inherited neurological disorder 47 dopaminergic 47 EZH2 47 Iruela Arispe 47 Nod1 47 causative mutations 47 deCODE AF TM 47 Dr. Fred Volkmar 47 histone modifications 47 pathophysiological 47 Fas ligand 47 hypermethylation 47 familial predisposition 47 Hedgehog pathway 47 genes gene mutations 47 TGF ß 47 Progenitor Cells 47 endocannabinoid signaling 47 mechanistic insights 47 upregulation 47 PARP1 47 NPM1 47 hypometabolism 47 neural mechanisms 47 HCV replication 47 anti apoptotic 47 haplotyping 47 constitutively expressed 47 Klotho gene 47 E#F# 47 small molecule activators 47 UCP2 47 Grigori Enikolopov 47 monocytes macrophages 47 PKM2 47 transgenic rats 47 adipokines 47 ABCB1 47 leptin receptors 47 peptide hormone 47 dopaminergic neurons 47 MDSCs 47 dysbindin 47 NKT cell 47 maladaptive behaviors 47 maternally inherited 47 Polymorphisms 47 deCODE Glaucoma TM 47 TGF β1 47 Asperger syndrome Rett syndrome 47 comorbid disorders 47 Transcription Factor 47 genetically altered mice 47 amyloidogenic 47 nitric oxide synthase 47 LPA receptors 47 commercialize deforolimus 47 sterol regulatory 47 diagnostic biomarker 47 epithelial barrier 47 CYP#C# [002] 47 Matthew Meyerson 47 Rowitch 47 primary cilia 47 ectopic expression 47 NASH Huntington 47 neurotrophin 47 protease activated 47 experimental autoimmune encephalomyelitis 47 susceptibility locus 47 receptor antagonism 47 RNA splicing 47 biopsychosocial model 47 flavopiridol 46 Transcriptome 46 adhesion molecule 46 GRNCM1 46 innovative microdroplet based 46 brain plasticity 46 neuroprotective effects 46 STK# gene 46 androgen receptor AR 46 follistatin 46 naturally occurring enzyme 46 neuropsychological assessment 46 mGluR5 inhibition 46 Lewy Bodies DLB 46 genetic polymorphism 46 caveolin 46 Prolactin 46 Bucindolol 46 mediated apoptosis 46 ENMD # 46 Immunohistochemical analysis 46 BDNF 46 NF kB pathway 46 naturally occurring neuroprotective 46 author Karin Michels 46 cardiac channelopathies 46 MYH9 gene 46 Notch1 46 CXCR7 46 p#Kip# 46 Fc receptor 46 MetAP2 46 DLC1 46 ski lls 46 activate AMPK 46 naturally occurring molecule 46 organophosphorus compounds 46 Transcriptional 46 nucleic acids DNA 46 TRPV4 46 activin 46 JNK1 46 selective angiogenic kinase inhibitor 46 induced apoptosis 46 hormone secretion 46 mechanistic explanation 46 Therapeutic Potential 46 complex neurobiological disorder 46 aberrantly activated 46 Dr. Victor Velculescu 46 KLF4 46 acetylcholinesterase AChE 46 meta cognitive 46 anti fibrotic 46 receptor gamma 46 hypomethylation 46 K ras mutations 46 lymphotoxin 46 Gomez Pinilla 46 cholinergic tone 46 LRAT 46 prognostic marker 46 actin cytoskeleton 46 neuropsin 46 Nicotinic 46 cause cardiac channelopathies 46 Protein Interactions 46 proapoptotic 46 phosphatases 46 TNF receptors 46 FMRP 46 nAChR 46 glycogen synthase kinase 46 C1q 46 gene predisposing 46 NKG2D 46 oxysterols 46 susceptibility genes 46 Symadex 46 TNFa 46 Polychronakos 46 selective modulator 46 TNFalpha 46 CCL5 46 breast cancer metastasis 46 glycosyltransferase 46 Pulsing multicolored diodes 46 Velculescu 46 selective kinase inhibitors 46 AgRP 46 mitochondrial toxicity 46 laforin 46 Smoothened 46 Cytotoxic T 46 prognostic biomarkers 46 DGAT 46 TLR3 46 SIRT1 46 ERK2 46 DQB1 * 46 Aâ 46 MicroRNA 46 eNOS 46 JAK3 46 Metabolic Disease 46 neurosteroids 46 antitumor effects 46 dopamine D2 receptors 46 mGlu2 3 46 pancreas secretes insulin 46 Phosphorylation 46 code Cu AA# 46 Apobec3 46 repetitive stereotyped 46 predictive biomarker 46 circadian cycles 46 Viprovex TM 46 caveolin 1 46 acetylcholine receptor 46 Novel Mechanism 46 Amato Giaccia 46 genetic polymorphisms 46 cannabinoid receptor 46 NMDA receptors 46 posttranslational modifications 46 NEDD9 46 inherited metabolic disorders 46 tumor suppressors cytokines 46 AclarusDx 46 hormones leptin 46 Wwox 46 IGFBP 3 46 SNCA 46 Kenneth Kinzler 46 Pericak Vance 46 BDNF gene 45 phosphorylated tau 45 asperger syndrome 45 enzyme AMPK 45 multidrug resistance 45 FOXO 45 atherosclerotic cardiovascular 45 SR B1 45 endocannabinoid system 45 differential gene expression 45 previously uncharacterized 45 upregulating 45 antisense therapies 45 Kari Stefansson CEO 45 lymphocyte activation 45 HDAC6 45 airway reactivity 45 Neurotransmitter 45 familial adenomatous polyposis 45 PTHrP 45 perilipin 45 OCT4 45 APOE4 45 Developmental Therapeutics Program 45 Androgen Receptor 45 PTP 1B 45 Preclinical Study 45 Aurora Kinase 45 NR#A# 45 DNA hypomethylation 45 DNA Methylation 45 IL 1β 45 gliosis 45 Brain Derived Neurotrophic 45 MLL2 45 ALK inhibitors 45 metacognitive 45 transfusion syndrome 45 histone methyltransferase 45 HBx 45 ENaC 45 IDH1 mutation 45 SIX RO ROG 45 Lisofylline 45 FUS protein 45 circadian genes 45 enzymatic activity 45 BRIP1 45 IL#R 45 Smac mimetic 45 spinocerebellar ataxia type 45 PI3K pathway 45 nasopharyngeal carcinoma NPC 45 Histone 45 APOL1 45 ASIC1a 45 TLR4 45 insulin receptors 45 HOTAIR 45 progranulin protein 45 HepG2 cells 45 IL 1ß 45 heme oxygenase 1 45 CINQUIL 45 Donald O. Schnuck 45 KIAA# 45 CYP#E# 45 inducible nitric oxide synthase 45 induce apoptosis 45 Single Nucleotide Polymorphisms SNPs 45 hypocretin 45 susceptibility loci 45 Charles DeCarli 45 CREB protein 45 neurobiological disorders 45 PECAM 1 45 metabolomic profile 45 Hepatotoxicity 45 neuro musculoskeletal 45 osteocalcin 45 Victor Velculescu 45 Androgen 45 PTP1B 45 neuroimaging studies 45 Cancer Genome 45 protein conformation 45 masculinizing 45 extracellular dopamine 45 biologically plausible 45 Apc 45 prostanoid 45 Myc oncogene 45 COL#A# 45 drug metabolizing enzymes 45 molecular profiling 45 Dopaminergic 45 ChR2 45 PPAR alpha 45 ropinirole Requip 45 Piomelli 45 X Chromosome 45 TGF beta signaling 45 B Raf 45 noncoding RNAs 45 Dendritic cell 45 Magdalena Götz 45 beta actin 45 BRAF V#E 45 alpha7 45 gene loci 45 diagnostics therapeutics 45 Schoppe Sullivan 45 dopamine neurotransmission 45 cyclin dependent kinase inhibitor 45 Genetic Variation 45 Microtubule 45 inactivating mutations 45 HIF 1alpha 45 P2X 45 nicotinic receptor 45 HLA DQ2 45 Diana Schendel 45 causal variants 45 Rap1 45 leukemia aplastic anemia 45 chemokine receptors 45 WNK1 45 Derek Besenfelder 45 excitatory neurotransmitter glutamate 45 uPAR 45 EC Cysteamine 45 mGluRs 45 GSK 3ß 45 situ hybridization ISH 45 splice junctions 45 Cognitive behavioral 45 NKT cells 45 heritable genetic 45 Consortium ICGC 44 progressive neurodegenerative disorders 44 SLC#A# [002] 44 sickle cell hemoglobin 44 deCODE ProstateCancer TM 44 IGF2 44 multigene 44 inverse agonist 44 β1 44 S#A# [002] 44 regenerative therapy 44 PTPN# 44 Psynova 44 JAK2 44 myocyte 44 VEGF receptor 44 diagnose coronary artery 44 Morrison Bogorad 44 Psychosocial interventions 44 pDC 44 developmental dyscalculia 44 obsessive compulsive behaviors 44 chromosome #q#.# [001] 44 splice variants 44 TNFα 44 PPARgamma 44 inhibitory receptor 44 MSH2 44 Antithrombin 44 receptor tyrosine kinase 44 Metagenomics 44 autism Asperger Syndrome 44 Fragile X gene 44 FKBP# 44 MeCP2 44 MAPK signaling pathway 44 glucocorticoid 44 Safinamide 44 monoamine 44 Aldosterone 44 receptor subtypes 44 5 HT4 receptor 44 antiproliferative activity 44 myeloproliferative 44 glucocorticoid receptors 44 Dpp 44 endogenous ligands 44 premorbid 44 genomic biomarkers 44 JAK STAT 44 Allosteric 44 Markus Stoffel 44 functional polymorphism 44 autosomal recessive disease 44 CYP#B# 44 humanized monoclonal antibodies 44 NFκB 44 Dr. Hakon Hakonarson 44 predictive biomarkers 44 cerebrospinal fluid biomarkers 44 Brain derived neurotrophic 44 cognitive affective 44 Volkow explains 44 NECK CANCER SUPPORT GROUP 44 RIP1 kinase 44 biochemical profiling 44 selective inhibitors 44 TCF#L# 44 exome sequencing 44 Signaling Pathways 44 coreceptor 44 granzyme B 44 Gene Expression Laboratory 44 matrix metalloproteinases 44 estrogen receptor beta 44 anatomical physiological 44 constitutively active 44 Genetic Predisposition 44 See CLINICAL PHARMACOLOGY 44 biomarker assays 44 Transgenic Mice 44 catenin 44 homodimers 44 androgen receptor pathway 44 RECALL VAX vaccine 44 microRNA miR 44 bile acid metabolism 44 HBV HCV 44 urologic pathology 44 SLITRK1 44 CYP #D# 44 modulatory 44 Dr. Bert Vogelstein 44 Randi Hagerman 44 demethylase 44 TRIM5a 44 dysgraphia 44 serotonin transporter 44 maladaptive coping