Related by context. All words. (Click for frequent words.) 77 leukopenia 77 neutropaenia 76 leucopenia 74 hematologic toxicity 73 neutropenia thrombocytopenia 73 febrile neutropenia 73 hypophosphatemia 72 Neutropenia 72 myelosuppression 71 sensory neuropathy 71 FluCAM arm 71 haematologic 71 thrombocytopenia 71 fatigue asthenia 71 thrombocytopenia neutropenia 71 laboratory abnormalities 71 cytopenias 71 peripheral sensory neuropathy 71 incidence ≥ 70 non hematological toxicities 70 neutropenia dehydration dyspnea 70 hypokalemia 70 mucosal inflammation 70 â ‰ ¥ 69 neutropenia 69 pancytopenia 69 anemia neutropenia 68 Infusion Reactions Severe 68 myalgia arthralgia 68 pyrexia mucositis sepsis febrile 68 gastrointestinal toxicities 68 SGPT 68 nephrotoxicity 68 aspartate aminotransferase AST 68 ALT flares 68 alanine aminotransferase 68 neutropenia febrile neutropenia 68 lymphocytosis 68 anemia thrombocytopenia 68 REYATAZ r arm 68 hepatic enzymes 68 leukocytosis 68 TEAEs 67 acneform rash 67 Flu Cy 67 lopinavir r arm 67 thrombocytopenia anemia 67 neutrophil counts 67 severe neutropenia 67 serum urate levels 67 intravascular hemolysis 67 fatigue diarrhea nausea 67 transaminase elevations 67 QTc prolongation 67 HBeAg seroconversion 67 extrapyramidal symptoms 67 hyperalgesia 67 anemia hemoglobin 67 limiting toxicity 67 TNFalpha 67 CIN3 67 cytogenetic response 67 transaminases 67 symptomatic VTE 67 neutrophil count 67 events AEs 67 akinesia 67 hematologic adverse 67 bone marrow suppression 66 DLTs 66 histologic subtype 66 hematological toxicity 66 cytogenetic responses 66 pruritis 66 HBeAg negative patients 66 MCyR 66 aspartate aminotransferase 66 grade cervical intraepithelial 66 serum cortisol 66 ecchymosis 66 CR nPR 66 hematological adverse 66 asthenia 66 elevated ALT 66 hypocalcemia 66 alanine aminotransferase ALT 66 morphometric vertebral fractures 66 headache abdominal pain 66 arterial thromboembolic events 66 intracranial hemorrhage ICH 66 asthenia fatigue 66 histological subtype 65 Erythropoietic therapies may 65 paresthesias 65 ‰ ¥ 65 % CI #.#-#.# [007] 65 liver histology 65 dermatologic toxicities 65 headache nasopharyngitis 65 Febrile neutropenia 65 ovarian carcinoma 65 hypomagnesemia 65 receiving VICTRELIS 65 ALT elevations 65 dose limiting toxicities 65 prolonged QT interval 65 HER2 expression 65 lichen planus 65 hepatocellular carcinomas 65 Ribavirin causes 65 pCR 65 aminotransferases 65 neurological manifestations 65 anterior uveitis 65 complement inhibitor eculizumab 65 eosinophilia 65 HBeAg negative 65 triiodothyronine 65 dysuria 65 oxycodone CR 65 conjunctival hyperemia 65 thrombocytopenic 65 plus methotrexate 65 CR CRu 65 posttreatment 65 hepatic enzyme 65 stomatitis 65 gastrointestinal perforation 65 HBeAg positive 65 P = .# 65 gastric carcinoma 65 HER2 overexpression 65 macroalbuminuria 65 mcg BID 65 thrombocytosis 65 recurrent genital herpes 65 immunoreactivity 65 neovascular 65 myeloproliferative diseases 65 hypoperfusion 65 rhinorrhea 65 neurologic complications 65 LV dysfunction 65 constipation nausea 65 ACTEMRA TM 65 Myelosuppression 65 CP CPPS 64 Hypotension 64 pyrexia 64 ALT elevation 64 Toxicities 64 AST ALT 64 hypercalcemia 64 pericardial effusion 64 dysmenorrhoea 64 hepatotoxicity 64 nausea vomiting headache 64 unfavorable cytogenetics 64 IGFBP 3 64 ara C 64 hyperintensities 64 virologic breakthrough 64 mucositis 64 microvascular complications 64 APTIVUS r 64 discontinuations due 64 ertapenem 64 MALT lymphoma 64 serum phosphate 64 cutaneous squamous cell carcinoma 64 nasopharyngitis headache 64 Sjögren syndrome 64 experienced hypomagnesemia 64 relapsed MM 64 somatostatin analog 64 neurologic dysfunction 64 hematologic toxicities 64 Dose limiting toxicities 64 inducible nitric oxide synthase 64 IL 1ß 64 del 5q MDS 64 intratumoral 64 Thrombocytopenia 64 hematological toxicities 64 nadolol 64 interleukin IL -6 64 rebleeding 64 leukemia AML 64 neutropenic fever 64 adjunctive placebo 64 proctitis 64 Dermatologic toxicities 64 epithelial tumors 64 CIN2 64 recurrent glioblastoma multiforme 64 hematologic 64 HBeAg 64 mg kg dose 64 doxorubicin cyclophosphamide 64 paragangliomas 64 sarcomatoid 64 PREZISTA r arm 64 clinically meaningful reductions 64 LPS induced 64 pruritus 64 transaminase 64 ADPKD 64 tumor xenograft models 64 PAOD 64 BPH benign prostatic 64 NAbs 64 recurrent VTE 64 moderate renal impairment 63 genotypic resistance 63 somnolence fatigue 63 SGOT 63 lumbar spine BMD 63 nodal metastases 63 hyperprolactinemia 63 overt nephropathy 63 DOXIL 63 interleukin IL -# 63 CD8 + 63 lamivudine refractory patients 63 HBeAg positive patients 63 amenorrhoea 63 achieved ACR# 63 dermatologic reactions 63 serum ALT 63 haematological toxicity 63 tumor lysis syndrome 63 tumor regressions 63 cTnI 63 achieved statistical significance 63 cervical intraepithelial neoplasia 63 erythema redness 63 corticosteroid therapy 63 colorectal adenoma 63 invasive ductal 63 serum potassium 63 serum HBV DNA 63 K ras mutations 63 SSc 63 receiving ISENTRESS 63 CCyR 63 pruritus itching 63 homozygotes 63 TNF α 63 pheochromocytoma 63 pT3 63 hemoglobin Hb 63 CIMZIA TM certolizumab pegol 63 invasive carcinomas 63 mg/m2 dose 63 tryptase 63 locoregional 63 Histologic 63 dose dependently 63 isoproterenol 63 vWD 63 patients receiving ERBITUX 63 EXJADE 63 lymphadenopathy 63 prednisone prednisolone 63 isoenzyme 63 ^ sup #m 63 μg ml 63 Sezary syndrome 63 autoantibody positive 63 tapentadol ER 63 arthralgias 63 % CI #.#-#.# [003] 63 p = NS 63 thyrotoxicosis 63 diarrhea nausea vomiting 63 CIMZIA ™ 63 MADRS score 63 Stomatitis 63 receiving XGEVA 63 chronic eosinophilic leukemia 63 euthymic patients 63 TIMP 1 63 8mg/kg 63 hyperphenylalaninemia HPA due 63 essential thrombocythemia 63 FDG uptake 63 plasma creatinine 63 graft dysfunction 63 treatment emergent adverse 63 CIN2 + 63 Hematologic 63 tumoral 63 chronic idiopathic 63 alveolar epithelial cells 63 evaluable subjects 63 metastatic neuroendocrine tumors 63 serum testosterone 63 haemolysis 63 colorectal carcinoma 63 recurrent venous thromboembolism 63 metastatic GIST 63 virologic responses 63 hypopituitarism 63 pericardial effusions 63 hallucinations dyskinesia 63 BARACLUDE ® 63 cough dyspnea 63 virological response 63 serum IGF 63 alpha interferons 63 malignant neoplasm 63 hypoglycaemic episodes 63 Leydig cell 63 cytokeratin 63 thromboembolic events 63 generalized edema 63 deletion 5q 63 biochemical relapse 63 TTR gene 63 Nausea vomiting 63 neoplasm 62 serum creatinine levels 62 ispinesib administered 62 renal insufficiency 62 serum calcium levels 62 caspofungin 62 trimethoprim sulfamethoxazole 62 Subgroup analysis 62 elevated bilirubin 62 GOUT 62 antiphospholipid syndrome 62 neutropenic patients 62 hyperreflexia 62 postoperative chemotherapy 62 MACCE 62 liver transaminases 62 pmol L 62 Hashimoto thyroiditis 62 ≥ 62 autonomic dysfunction 62 elevated LDH 62 VAPRISOL 62 mg BID dose 62 undetectable HBV DNA 62 hepatitis C genotype 62 hemorrhagic complications 62 ERalpha 62 Index CDAI 62 desvenlafaxine succinate 62 CTAP# Capsules 62 Pred Forte 62 posttransplant 62 thromboembolic complications 62 severe NCI CTC 62 haematological 62 monocytic 62 myalgias 62 metabolic alkalosis 62 hypothalamic pituitary 62 hepatic fibrosis 62 acromegalic patients 62 osteoclastic 62 Telintra 62 elevated creatinine 62 chlorambucil 62 neutropenic 62 infusion reactions 62 hemorrhagic cystitis 62 highly emetogenic 62 timepoints 62 endometrial carcinoma 62 bronchoalveolar lavage 62 TT genotype 62 hyperintensity 62 chloride secretion 62 somnolence sedation 62 glycated hemoglobin levels 62 severe rotavirus gastroenteritis 62 K#N 62 inflammatory lesions 62 airway hyper responsiveness 62 CD4 CD8 62 patients evaluable 62 Akt activation 62 neutropenia anemia 62 LymphoStat B belimumab 62 rosuvastatin #mg 62 hemoptysis 62 lymphovascular invasion 62 doxorubicin docetaxel 62 stage IIIB 62 lactate dehydrogenase 62 splenectomized 62 elevated IOP 62 antiemetics 62 pulmonary arterial 62 hyperglycaemia 62 partial remissions 62 composite endpoint 62 neoplasias 62 HbA 1c levels 62 PASI scores 62 gastric adenocarcinoma 62 eosinophil count 62 immunocompetent patients 62 comparator arm 62 ischemic lesions 62 μmol L 62 FOLPI 62 complete cytogenetic response 62 Psoriasis Area 62 B7 H3 62 vasogenic edema 62 mycophenolate mofetil 62 Hurthle cell 62 PSA nadir 62 hyperoxaluria 62 syncope fainting 62 lenalidomide dexamethasone 62 somnolence dizziness 62 myelofibrosis polycythemia vera 62 myeloproliferative neoplasms 62 hepatocellular 62 Lupus nephritis 62 cerebrovascular events 62 hypercholesterolaemia 62 affective psychosis 62 prothrombotic 62 hemodilution 62 thromboembolic 62 de novo AML 62 vesicoureteral reflux 62 hip BMD 62 antiandrogens 62 dyspareunia 62 HIV HCV coinfected 62 atrioventricular block 62 CYP #A# 62 HbF 62 peripheral edema 62 TNF antagonist 62 Immunohistochemical analysis 62 extrapyramidal disorder 62 carcinoids 62 severe hypersensitivity reactions 62 metastatic malignant 62 pleural effusion 62 mucocutaneous reactions 62 GISTs 62 nasopharyngitis 62 immunostaining 62 non metastatic osteosarcoma 62 unstable angina pectoris 62 dacarbazine DTIC 62 coronary stenosis 62 RBC transfusion 62 cTnT 62 uM 62 recurrent UTI 62 node metastases 62 hypercalcaemia 62 idiopathic thrombocytopenic purpura 62 elevated triglyceride levels 62 splenic 62 paresthesia 62 urinary N telopeptide 62 tumor histology 62 tolvaptan 62 headache nausea fatigue 62 plasma leptin 62 myeloproliferative disorder 62 unresectable HCC 62 peritumoral 62 leukemia ALL 62 mdx mice 62 x ULN 62 serum sodium 62 pathologic fractures 62 esophageal carcinoma 62 intact parathyroid hormone 62 lumbar spine bone 62 tumor necrosis 62 novel VDA molecule 61 virologic failure 61 IFN γ 61 apo B 61 urothelial carcinoma 61 sonographically 61 anemia leukopenia 61 demyelinating 61 refractory gout 61 prostate cancer CaP 61 coadministration 61 epistaxis 61 biochemical recurrence 61 tipranavir ritonavir 61 heavily pretreated 61 periventricular leukomalacia 61 alanine transaminase 61 lymph node metastasis 61 basal cell carcinoma BCC 61 % AST SGOT 61 candidemia 61 serum phosphate levels 61 platelet reactivity 61 postoperative complication 61 detrusor 61 CANCIDAS 61 locoregional recurrence 61 Tumor shrinkage 61 daunorubicin 61 aortic insufficiency 61 parasitaemia 61 glutamyl 61 vWF 61 posaconazole 61 teriflunomide 61 detrusor overactivity 61 adriamycin 61 non splenectomized 61 SCr 61 inotropic 61 PaO 2 61 Chemotherapy induced 61 intravesical therapy 61 carcinoembryonic antigen 61 p# activation 61 clinically meaningful improvement 61 IFN beta 61 proliferative diabetic retinopathy 61 hyperacute 61 intestinal metaplasia 61 palmar plantar 61 fatigue abdominal pain 61 external genital lesions 61 squamous cell carcinoma SCC 61 aminotransferase ALT 61 Diabetic neuropathy 61 SUVmax 61 EDSS scores 61 Ki# 61 4mg/kg 61 skeletal metastases 61 leukocyte counts 61 p = .# [002] 61 serum aminotransferase levels 61 baseline LDH 61 apolipoprotein B 61 FOLFOX6 61 ritonavir boosted 61 severe exacerbations 61 cisplatin chemotherapy 61 CsA 61 CC genotype 61 #q# deletion syndrome 61 Primary endpoints 61 lactate dehydrogenase LDH 61 log# copies mL 61 Serious adverse reactions 61 myoclonus 61 cell adhesion molecule 61 nonhematologic adverse reactions 61 angioneurotic edema 61 univariate analysis 61 hyperinsulinemia 61 bladder carcinoma 61 metabolic acidosis 61 atrophic gastritis 61 solifenacin 61 nodular 61 transgene expression 61 mild renal insufficiency 61 fallopian tube cancers 61 dexrazoxane 61 VELCADE melphalan 61 torsade de pointes 61 KRAS mutations occur 61 oesophagitis 61 treatment emergent AEs 61 NNRTI resistance 61 IFN α 61 serum estradiol 61 adjunctive ABILIFY 61 octreotide LAR 61 liver decompensation 61 advanced adenoma 61 ischaemia 61 IGFBP 61 bullous 61 serum homocysteine 61 CD4 ^ sup 61 intracranial hypertension 61 mcg kg REBETOL 61 alkaline phosphatase 61 lipid elevations 61 steroidogenic 61 mg BID 61 follicular lymphomas 61 hepatorenal syndrome 61 aplastic anemia AA 61 isoprostane 61 rheumatoid factor 61 HGPIN 61 alpha2 61 Vaprisol 61 overt hypothyroidism 61 intravitreal injections 61 nonfatal MI 61 5-FU/LV 61 thyroid carcinoma 61 mRNA expression 61 multivariate adjustment 61 plasma folate 61 intraventricular 61 peginterferon alfa 61 PSADT 61 neurodevelopmental impairment 61 baseline HbA1c 61 tipranavir r 61 interferon alfa 2b 61 histologic 61 serum urate 61 interferon γ 61 prostate carcinoma 61 hamartomas 61 hyperbilirubinemia 61 myopathy rhabdomyolysis 61 HDRS 61 lesional 61 % Confidence Interval 61 headache nausea diarrhea 61 proteinuria 61 Bacterial vaginosis 61 seropositive patients 61 peritumoral brain edema 61 neurologic symptoms 61 platinum refractory 61 cardiac troponin 61 xenograft tumors 61 erythrocyte sedimentation rate 61 esophagitis 61 induce orthostatic hypotension 61 placebo dexamethasone 61 serum parathyroid hormone 61 hypercalciuria 61 ANCA associated 61 decitabine 61 anaphylactic reactions bronchospasm 61 Gram stain 61 capillary leak 61 primary aldosteronism 61 granulomatous 61 mcg albinterferon alfa 2b 61 sulfasalazine 61 perioperatively 61 hepatic encephalopathy HE 61 mutated KRAS 61 serum prostate 61 seminomas 61 renal toxicity 61 muscarinic receptors 61 hypopigmentation 61 PRADAXA #mg 61 hematological parameters 61 phosphorylated tau 61 hypercoagulable 61 β blockers 61 IL 1β 61 AGILECT R 61 T#I [002] 61 CHOP chemotherapy 61 pamidronate 61 Crohn Disease Activity 61 lymphocytic 61 affective psychoses 61 TMP SMX 61 TRAIL R1 61 thromboembolism 61 metastatic carcinoid tumors 61 osteosarcomas 61 steroid dexamethasone 61 bcr abl 61 purpura 61 LHRH agonists 61 elevated transaminases 61 lymphocyte counts 61 autoantibody levels 61 TRAIL R2 61 heavily pretreated patients 61 Follicular Lymphoma 61 PEGylated anti 61 distant metastasis 61 induced apoptosis 61 precancerous cervical lesions 61 PsA 61 hepatic dysfunction 61 enteroviral infection 61 neurosensory 60 hypertensives 60 umol L 60 Known hypersensitivity 60 nanomolar 60 clinicopathological features 60 E selectin 60 demonstrated antitumor activity 60 Doxil ® 60 Gleevec resistant 60 paraprotein 60 plus gemcitabine 60 nodular partial response 60 hyperkalemia 60 cardiac dysfunction 60 reactogenicity 60 Postoperative complications 60 urinary oxalate 60 hypothalamic pituitary adrenal axis 60 hypoxemia 60 Renal impairment 60 relapsed acute myelogenous 60 adrenal suppression 60 generalized tonic clonic seizures 60 Hypokalemia 60 leukocyte count 60 mL/min/#.# m 2 60 mucinous 60 Asymptomatic 60 diarrhea headache nausea 60 microglial activation 60 antiangiogenic therapy 60 biologic DMARD 60 immune thrombocytopenic purpura 60 imatinib resistant 60 erythropoietic 60 TMC# r 60 salmeterol HFA MDI 60 HT 2A 60 perioperative complications 60 proteoglycan 60 pulmonary toxicity 60 hypertrophic scars 60 cytopenia 60 pyridostigmine 60 receptor tyrosine kinase inhibitor 60 pegIFN 60 post transplant lymphoproliferative 60 ALT normalization 60 salmeterol fluticasone 60 definite stent thrombosis 60 squamous 60 B Cell Lymphoma 60 antibody titer 60 FOLFOX4 60 serum calcium 60 imatinib therapy 60 complete remissions 60 renal cell carcinomas 60 postintervention 60 CD#c 60 aplasia 60 rCBF 60 periprocedural 60 artery stenosis 60 androgen suppression 60 virologic response 60 CIMZIA TM 60 Non Alcoholic Steatohepatitis 60 IL 1beta 60 liver metastasis 60 HepG2 cells 60 cholecystitis 60 gastroduodenal 60 corrected QT interval 60 demyelination 60 pegylated liposomal doxorubicin 60 Diffuse Large B 60 melphalan prednisone 60 acute GvHD 60 histologically 60 #ß 60 imipenem 60 underlying vasculopathy 60 Kinoid 60 INVEGA ® 60 AGILECT ® 60 lung metastases 60 proinflammatory cytokine 60 subtrochanteric 60 evaluable 60 dose cohort 60 plasma pharmacokinetics 60 #mg BID [001] 60 orthostatic hypotension 60 astrocytomas 60 abacavir lamivudine 60 Myelodysplastic Syndrome MDS 60 CMV infection 60 bacterial prostatitis 60 CK MB 60 acute coronary syndromes ACS 60 hormone receptor negative 60 refractory NSCLC 60 albumin excretion rate 60 trans retinoic acid 60 retrograde ejaculation 60 tolterodine ER 60 certolizumab 60 carotid stenosis 60 CD4 + CD# 60 glomerular filtration 60 CCR7 60 malignant neoplasms 60 % CI #.#-#.# [006] 60 NRTI resistance 60 monocyte chemoattractant protein 60 interferon IFN 60 parenchymal 60 QTcF 60 erythropoiesis 60 GH deficiency 60 pDC 60 alemtuzumab treated 60 neurologic deficits 60 arteriolar 60 leiomyomas 60 vasodilatation 60 seropositivity 60 mycosis fungoides 60 testicular tumors 60 GnRH agonist 60 ug dose 60 rFVIIa 60 intravenous cyclophosphamide 60 PDGFR 60 Xanafide 60 nausea dizziness vomiting 60 Postoperative 60 creatine kinase MB 60 liposomal amphotericin B 60 antibody titers 60 lactic acidosis 60 Peg IFN 60 interferon alfa 60 monocyte chemotactic protein 60 IFN gamma 60 peripheral blood mononuclear 60 #OHD 60 sJIA 60 normal karyotype 60 NMIBC 60 BRAF mutations 60 vasodilatory 60 androgen deprivation 60 hypogonadotropic hypogonadism 60 Tasigna prolongs 60 ventricular tachyarrhythmia 60 cell acute lymphoblastic 60 papillary thyroid carcinoma 60 ribavirin therapy 60 anaplastic astrocytomas 60 subclinical hypothyroidism 60 refractory AML 60 femoral neck fracture 60 prolactin levels 60 HLA DR 60 pT2 60 hyperparathyroidism 60 CD#b 60 proliferative retinopathy 60 hepatic cirrhosis 60 S. aureus isolates 60 C1 INH deficiency 60 hemolytic 60 fluvastatin 60 delayed CINV 60 Peripheral edema 60 effector function 60 systemic corticosteroid 60 HSCT 60 breast carcinomas 60 PTPN# 60 serum HCV RNA 60 idiopathic Parkinson disease 60 paclitaxel cisplatin 60 leiomyoma 60 thrombotic events 60 CLL SLL 60 plasminogen activator inhibitor 60 endometrial hyperplasia 60 haemolytic 60 radiographic findings 60 frequent awakenings 60 foveal thickness 60 serum leptin 60 N. gonorrhoeae 60 renal dysfunction 60 glomerulonephritis 60 pan HDAC inhibitor 60 lymphoproliferative disorder 60 ipsilateral stroke 60 events SAEs 60 unknown etiology 60 interleukin IL 60 generalized epilepsy 60 COPD exacerbation 60 heterozygotes 60 TNF Tumor Necrosis Factor 60 distant metastases 60 papillary 60 EGFR TKI 60 mitoxantrone plus 60 pleomorphic 60 fatigue nausea vomiting 60 ancrod 60 extrapyramidal symptoms EPS 60 pulmonary metastases 60 hypoglycemic events 60 chronic GVHD 60 progesterone receptor negative 60 5 HT1A 60 abdominal pain headache 60 delayed gastric emptying 60 aminotransferase 60 System IPSS 60 alfa 2a 60 Natalizumab 60 inflammatory acne 60 metastatic malignant melanoma 60 recurrent DVT 60 Bezielle 60 abnormal lipid 60 HCV genotypes 60 chronic hepatitis cirrhosis 60 methicillin susceptible Staphylococcus aureus 60 microvessel density 60 oxygen desaturation 60 rFSH 60 nM 60 Zometa hazard 60 VFEND 60 virological failure 60 myalgia 60 ATACAND 60 serum retinol 60 protein excretion 60 situ CIS 60 antiretroviral naïve 60 fatal anaphylactic 60 splenectomized patients 60 paricalcitol 60 chronic myeloid 60 clodronate 60 coinfection 60 chronic renal insufficiency 60 Ophena TM 60 receiving golimumab 60 parathyroid carcinoma 60 thrombophlebitis 60 Nonspecific 60 Th1 cells 60 hypervolemic hyponatremia 60 OAB symptoms 60 Cutaneous T 60 catecholamine 60 idraparinux 60 chemotherapy induced neutropenia 60 Hematologic toxicity 60 lymphocyte activation 59 serum triglycerides 59 vaso occlusive crisis 59 lower extremity amputation 59 serous ovarian cancer 59 cervical lymph nodes 59 constitutively active 59 nonischemic 59 Kaplan Meier analysis 59 Neovascular AMD 59 choroidal neovascularization CNV 59 advanced adenomas 59 specific antigen PSA 59 idarubicin 59 completely resected 59 choroidal 59 T2DM 59 hA# 59 radiation dermatitis 59 HIV RNA 59 chronic idiopathic urticaria 59 ULORIC 59 urticaria hives 59 Myelofibrosis 59 lymphoid organs 59 NAGS deficiency 59 thyrotropin 59 agonist induced 59 Pulmonary hypertension 59 vitreous floaters 59 micafungin 59 PTHrP 59 nonmelanoma skin cancers