Related by context. All words. (Click for frequent words.) 72 Montgomery Åsberg Depression 70 Global Impression CGI 70 subscale scores 68 subscales 68 EQ 5D 68 Rating Scale MADRS 67 UPDRS 67 PANSS 67 Brief Psychiatric 67 MADRS score 66 Health Assessment Questionnaire 66 BPRS 65 Distress Scale 65 NIH CPSI 65 SGRQ 64 Visual Analogue Scale VAS 64 APACHE II 64 Montgomery Asberg Depression 64 subscores 64 MADRS 64 IBDQ 64 Visual Analog 64 Neuropsychiatric Inventory 64 Symptom Checklist 64 Pain Intensity 64 symptom severity 64 MMSE score 63 HAM D# 63 HRQL 63 euthymic patients 63 ADAS cog 63 YMRS 63 Hamilton Rating Scale 63 subscore 63 WOMAC 63 PANSS total 63 Inventory BPI 63 Rating Scale BPRS 63 depressive symptom 62 MMSE 62 biopsy Gleason 62 Abnormal Involuntary Movement 62 â ‰ ¥ 62 CORE OM 62 Depression Scale HADS 62 WOMAC pain 62 Y BOCS 62 somatic symptoms 62 Functional Assessment 62 HDRS 62 HAMD 62 HRQoL 62 UPDRS motor 61 Brief Pain 61 comorbid depression 61 mRS 61 HRQOL 61 Incontinence Impact Questionnaire 61 interrater reliability 61 BMI z 61 Status Scale EDSS 61 Visual Analogue Scale 61 State Examination MMSE 61 Clinician Administered PTSD 61 syndromal 61 Fibromyalgia Impact Questionnaire 61 psychometric properties 61 QoL 61 Expanded Disability Status 61 Beck Anxiety Inventory 61 Index CDAI 61 Subscale 61 PSQI 61 Scale PANSS 61 dyspnoea 61 International Prostate Symptom 60 Global Impression Severity 60 subsyndromal 60 Rating Scale UPDRS 60 KOOS 60 NYHA functional class 60 Alzheimer Disease Assessment 60 Crohn Disease Activity 60 somatization 60 pain subscale 60 State Trait Anxiety 60 Main Outcome Measures 60 Unified Parkinson Disease 60 Comorbidity 60 VFQ 60 Negative Syndrome 60 Visual Analog Scale 60 headache abdominal pain 60 Global Impression 60 Glasgow Coma Scale 60 Acute Physiology 60 cognitive affective 59 affective psychosis 59 non menstrual pelvic 59 Depression Inventory 59 depressive symptomatology 59 affective disorders 59 IRLS 59 QIDS SR 59 alexithymia 59 cough dyspnea 59 Hamilton Anxiety Scale 59 function subscale 59 DAS# CRP 59 Pain Rating Scale 59 erection hardness 59 hepatic enzyme 59 rhinoconjunctivitis 59 Disease Activity 59 psychosocial functioning 59 BILAG 59 SGPT 59 = #.#-#.# 59 WAIS III 59 #q# deletion syndrome 59 emotional lability 59 covariate 58 Depression Scale 58 GERD symptom 58 episodic migraine 58 FACIT Fatigue 58 nasal symptom 58 IRLS score 58 Ocular Surface Disease 58 Symptom severity 58 SELENA SLEDAI 58 interobserver reliability 58 ASIA Impairment 58 hypochondriasis 58 PHQ 9 58 NNT = 58 adjunctive placebo 58 serum cortisol 58 preoperative PSA 58 Score DAS 58 Oswestry Disability Index 58 Score TOS 58 Numeric Rating Scale 58 #OHD 58 Rating Scale 58 somatization disorder 58 autonomic dysfunction 58 NPRS 58 symptomatology 58 abdominal pain abdominal discomfort 58 MoxDuo TM IR 58 apnea hypopnea index 58 Physical Component 58 IIEF 58 Depression Inventory BDI 58 point Likert scale 58 Heritability 58 Generalized Anxiety Disorder 58 Global Impressions Severity 58 Chronic Illness Therapy 58 Preoperatively 58 x ULN 57 Geriatric Depression 57 Hopkins Symptom Checklist 57 left ventricular diastolic 57 psychiatric comorbidities 57 somatic complaints 57 SSRI SNRI 57 Main Outcome Measure 57 SF #v# 57 Severity Index 57 isoprostane 57 Scale EDSS score 57 ADHD RS 57 TNSS 57 adjunctive ABILIFY 57 WOMAC TM 57 clinically meaningful reductions 57 Severity Index PASI 57 urodynamic parameters 57 Charlson comorbidity index 57 tertiles 57 p = .# [002] 57 Stroke Scale NIHSS 57 McGill Pain Questionnaire 57 PANSS Positive 57 coronary stenosis 57 PREZISTA r arm 57 Depressive Symptoms 57 generalized epilepsy 57 psychiatric comorbidity 57 NIHSS 57 Escitalopram 57 Dyspnea 57 univariate analyzes 57 ADHD Rating Scale 57 substance induced psychosis 57 parkinson disease 57 Scale Cognitive Subscale 57 confidence intervals CIs 57 multivariable analysis 57 parkinsonian 57 euthymic 57 Mental Component 57 Anxiety Depression 57 convergent validity 57 somatoform disorders 56 odds ratios ORs 56 Pearson correlation coefficient 56 CI -#.# 56 Scale EDSS 56 paresthesias 56 Cronbach alpha 56 vasomotor 56 hyperarousal 56 SRBD 56 β = 56 ADCS CGIC 56 logistic regression model 56 plasma cortisol 56 Mania Rating Scale 56 Orthostatic Hypotension 56 posttreatment 56 Negative Symptoms 56 Rosenberg Self Esteem 56 Seattle Angina Questionnaire 56 HAQ DI 56 apnea hypopnea 56 Wechsler Adult 56 ADAS Cog 56 elevated LDH 56 Mood disorders 56 baseline PASI 56 neutropaenia 56 bronchial hyperresponsiveness 56 Comorbid 56 DAS# [002] 56 aspartate aminotransferase 56 cortical atrophy 56 subjective sleepiness 56 subscale 56 logistic regression analyzes 56 Symptom Scale 56 pretest probability 56 MMSE scores 56 mucosal inflammation 56 erosive GERD 56 oxycodone CR 56 secondary efficacy endpoint 56 mg XP# 56 urinary N telopeptide 56 tipranavir r 56 receiving VICTRELIS 56 posttraumatic 56 DAS# scores 56 hypersomnia 56 Postoperative 56 % CI #.#-#.# [003] 56 CNS LS 56 comorbid anxiety 56 Functional Outcomes 56 mL/min/#.# m 2 56 poststroke 56 somatostatin analog 56 STAI 56 clinically meaningful improvement 56 Comorbidities 56 HAM D 55 Symptom Severity 55 ‰ ¥ 55 CFQ R 55 salmeterol fluticasone 55 premorbid 55 mmol L. 55 % Confidence Interval 55 albumin excretion rate 55 PANSS scores 55 Disord 55 sensory neuropathy 55 CHADS2 55 ANOVA 55 NIS LL 55 symptomatic intracranial hemorrhage 55 Symptom 55 HOMA IR 55 ADCS ADL 55 haematologic 55 interobserver 55 enthesitis 55 State Exam MMSE 55 genitourinary GU 55 neutropenia thrombocytopenia 55 CDAI 55 untreated psychosis 55 Treatment Outcome 55 liver histology 55 Myalgia 55 extrapyramidal symptoms 55 BPS IC 55 overactive bladder syndrome 55 nonfatal MI 55 alanine aminotransferase 55 CIMZIA TM certolizumab pegol 55 affective psychoses 55 IPSS 55 F FDG PET 55 EORTC QLQ C# 55 EDSS score 55 linaclotide treated 55 Stomatitis 55 amisulpride 55 ALT elevations 55 Posttraumatic stress disorder 55 PASI scores 55 diabetes dyslipidemia 55 baseline FEV 55 schizophrenia schizoaffective disorder 55 Operative mortality 55 bivariate analysis 55 intelligence quotient IQ 55 SSRI citalopram 55 Ishak fibrosis score 55 sd = 55 subsyndromal depression 55 Index WOMAC 55 Symptom Score 55 psychosocial variables 55 Epidemiological Studies Depression 55 Respiratory Symptoms 55 CHADS 55 RENAL 55 comorbid disorders 55 salivary cortisol 55 ß = 55 highest tertile 55 suicide attempters 55 diabetes mellitus DM 55 Nonspecific 55 Severity MSCS score 55 unpaired t 55 Psoriasis Area 55 p = #.# [003] 55 Stroke Scale 55 Complicated Grief 55 WOMAC scores 55 fasting plasma 55 hypophosphatemia 55 mcg QD 55 mTSS 55 Wechsler Memory 55 atherothrombotic disease 55 acute subacute 55 Schizoaffective Disorder 55 bivariate analyzes 55 diastolic pressures 55 Posttraumatic 55 multivariable adjusted 55 ALS Functional 54 Neurocognitive 54 sertraline Zoloft 54 SGOT 54 postinjury 54 tapentadol IR 54 ANCOVA 54 posttest 54 hip BMD 54 REYATAZ r arm 54 leukocyte counts 54 intraobserver 54 intraclass correlation coefficient 54 % CI #.#-#.# [007] 54 dichotomized 54 logistic regression analysis 54 FluCAM arm 54 Primary endpoints 54 Depression Anxiety 54 postoperative complication 54 nausea photophobia 54 echocardiographic parameters 54 Non inferiority 54 primary aldosteronism 54 HbA 1C 54 psychiatric outpatients 54 nadroparin 54 symptom checklist 54 QRS duration 54 Depressive symptoms 54 mania hypomania 54 SCr 54 gastroduodenal 54 Injury Severity Score 54 logistic regression 54 Panic Disorder 54 df = 54 psychopathological symptoms 54 nmol L. 54 erythrocyte sedimentation rate 54 Cognitive dysfunction 54 antiepileptics 54 Major Depressive Disorder 54 -#.# ± [002] 54 Ejection Fraction 54 % CI #.#-#.# [008] 54 ECLS 54 dysuria 54 tryptophan depletion 54 Depression Rating Scale 54 GH deficiency 54 idiopathic Parkinson disease 54 dysmenorrhoea 54 urine albumin 54 pain catastrophizing 54 oesophagitis 54 aminotransferase 54 FDG PET imaging 54 Cholinesterase Inhibitors 54 histological subtype 54 laboratory abnormalities 54 Epworth Sleepiness Scale 54 aldosterone antagonist 54 Dysmenorrhea 54 psychiatric morbidity 54 PCWP 54 aminotransferase levels 54 Lower Limb 54 lowest tertile 54 convulsive disorders 54 leucopenia 54 receiving Vectibix monotherapy 54 Fluvoxamine 54 Gastroesophageal Reflux 54 Social Phobia 54 chi squared 54 vitreous floaters 54 neuropsychological functioning 54 lopinavir r arm 54 Child Behavior Checklist 54 Mini Mental 54 nonobese 54 neutropenia dehydration dyspnea 54 Hypertrophic 54 OSDI 54 elevated ALT 54 cerebrovascular disorders 54 Secondary efficacy endpoints 54 INVEGA ® 54 multivariable Cox 54 Neuropsychiatric Inventory NPI 54 ug kg 54 antidepressant efficacy 54 COPD exacerbation 54 severe exacerbations 54 Subtypes 54 primidone 54 Urogenital Distress Inventory 54 univariate analysis 54 Likert scale 54 atherogenic dyslipidemia 54 schizophreniform disorder 54 nausea vomiting headache 54 daytime somnolence 54 constipation nausea 53 comorbid psychiatric 53 regression coefficient 53 CI #.#-#.# [001] 53 Danazol 53 clomipramine 53 vWD 53 PSA nadir 53 LV ejection fraction 53 retest reliability 53 desvenlafaxine succinate 53 prazosin 53 Likert 53 nasal polyposis 53 multivariate analyzes 53 CIBIC plus 53 P = .# 53 subclinical atherosclerosis 53 NIHSS score 53 unstable angina chest 53 Poisson regression 53 confusional 53 Neuropsychological 53 Univariate analysis 53 Nebulized 53 Edinburgh Postnatal Depression 53 semiquantitative 53 Decitabine 53 dyspareunia 53 P ≤ 53 HbA 1c 53 Hemoglobin A1c 53 International Prognostic Scoring 53 imipramine Tofranil 53 AUC0 53 Wilcoxon rank sum 53 CIN2 + 53 OSAHS 53 Spasticity 53 Neuroticism 53 pharyngolaryngeal pain 53 T2DM 53 4mg/kg 53 MDRD 53 intraclass correlation coefficients 53 treat NNT 53 Charlson Comorbidity Index 53 serum IGF 53 elevated creatinine 53 DAS# remission 53 DPNP 53 induce orthostatic hypotension 53 comorbidity 53 Univariate 53 Negative Symptom Scale 53 p = .# [001] 53 receiving ISENTRESS 53 mild renal insufficiency 53 pyridostigmine 53 neurologic impairment 53 DLQI 53 MCID 53 Non Responders 53 % CI #.#-#.# [004] 53 ischemia driven 53 CPAP adherence 53 artery stenosis 53 postintervention 53 Clinical Outcome 53 anticholinergic agents 53 Histologic 53 interpersonal psychotherapy 53 FACIT 53 aspartate aminotransferase AST 53 nonpsychotic 53 Prognostic 53 thrombocytopenia neutropenia 53 IKDC 53 PLMs 53 Retreatment 53 multiple linear regression 53 comorbid 53 Infusion Reactions Severe 53 bioavailable testosterone 53 serum urate levels 53 dysthymic disorder 53 interobserver agreement 53 HbA 1c levels 53 ACR Pedi 53 Mestinon 53 DSM IV diagnosis 53 Outcomes Study 53 Cronbach 53 unipolar depression 53 Kruskal Wallis test 53 Scale cognitive subscale 53 fluorodeoxyglucose positron emission tomography 53 insomnia somnolence 53 subtests 53 tapentadol ER 53 MCyR 53 psychoeducation 53 nondepressed 53 premenstrual dysphoric disorder 53 Score DAS# 53 IQR 53 neuropsychological assessment 53 p ≤ 53 arterial oxygen saturation 53 atherosclerotic renal artery stenosis 53 LPS induced 53 NYHA 53 asthenia 53 undetectable HBV DNA 53 serum TSH 53 lumbar spine BMD 53 EPDS 53 Lewy bodies DLB 53 HbA1C levels 53 polyarticular 53 reuptake inhibitor 52 neurologic dysfunction 52 generalized estimating 52 HER2 expression 52 Erosive Esophagitis 52 HIV HCV coinfected 52 symptomatic VTE 52 ALT elevation 52 Am J Cardiol 52 % CI #.#-#.# [005] 52 highly emetogenic 52 Common Toxicity Criteria 52 neuropathy sensory 52 Erectile Function IIEF 52 Chronic Migraine 52 ecchymosis 52 subtest 52 PERMP 52 atrioventricular block 52 apolipoprotein B 52 Physical Function 52 sUA 52 univariate 52 agomelatine 52 nmol l 52 radiographic findings 52 LDL cholesterol LDL 52 receiving XGEVA 52 urolithiasis 52 Severity Scale 52 Score IPSS 52 Skin sterol 52 EFFEXOR XR 52 correlation coefficients 52 antibody titer 52 psychodynamic psychotherapy 52 chronicity 52 diabetic polyneuropathy 52 divalproex sodium 52 nontraumatic 52 DSM IV TR 52 meta analytic 52 Psychodynamic 52 serum bicarbonate 52 fatigue asthenia 52 glycated hemoglobin 52 D Dimer 52 UPDRS Part III 52 Chronic Sinusitis 52 Index CDAI score 52 ACR# ACR# 52 myocardial viability 52 Kellgren Lawrence 52 severe NCI CTC 52 tubular atrophy 52 STRIDE PD 52 rhinorrhea 52 haematuria 52 pT3 52 LUTS 52 serum urate 52 detrusor 52 postop 52 Key secondary endpoints 52 alanine aminotransferase ALT 52 FEV ^ sub 52 avoidant personality disorder 52 TIMP 1 52 fluoxetine paroxetine 52 ejaculatory function 52 intact parathyroid hormone 52 nerve conduction velocity 52 Apolipoprotein 52 Interpersonal psychotherapy 52 neuroleptic 52 APOE genotype 52 Myocardial Infarction TIMI 52 Functioning GAF 52 hyperlipidaemia 52 hyperhomocysteinemia 52 comorbid diagnoses 52 amnestic MCI 52 dactylitis 52 hydroxy vitamin D 52 nonparametric 52 colorectal adenoma 52 logistic regression models 52 lymphopenia 52 Index FSFI 52 malignant neoplasm 52 thyrotropin levels 52 Likert pain 52 multiple logistic regression 52 abnormal ejaculation 52 HBeAg positive chronic hepatitis 52 glycosylated hemoglobin HbA1c 52 MSLT 52 HBeAg negative patients 52 hepatocellular carcinomas 52 Secondary endpoints 52 Chemotherapy induced 52 Cockcroft Gault 52 QIDS 52 Stratification 52 Obstructive sleep apnea OSA 52 neurologic complications 52 Biaxin R 52 clinicopathological 52 moderately emetogenic 52 Suicidal ideation 52 pulmonary dysfunction 52 Likert type 52 Meta Analysis 52 EDSS scores 52 serum magnesium 52 subthreshold 52 obstructive CAD 52 mcg mL 52 dermatologic toxicities 52 FDG uptake 52 #.#-#.# [011] 52 Clinical Dementia 52 advanced adenoma 52 bivariate 52 triiodothyronine 52 elevated IOP 52 LH FSH 52 serum estradiol 52 somnolence sedation 52 Maslach Burnout Inventory 52 nonsevere 52 serum bilirubin 52 acute mania 52 acute postoperative 52 achieved statistical significance 52 plasma pharmacokinetics 52 pairwise comparisons 52 conjunctival hyperemia 52 oxygen desaturation 52 χ 52 ertapenem 52 CR nPR 52 Helps Relieve 52 transcranial Doppler ultrasound 52 electroencephalographic 52 arterial thromboembolic events 52 sulfonamide 52 CDAI score 52 achieved ACR# 52 attain statistical significance 52 symptomatic hyponatremia 52 μg liter 52 Sociodemographic 52 serologically active patients 52 serum ALT 52 histologic subtype 52 Generalized anxiety disorder 52 Cardiotoxicity 52 lipid lowering agents 52 sociodemographic characteristics 51 depressive symptoms 51 Patients Receiving 51 categorical variables 51 Psychiatric Epidemiology 51 bronchopulmonary 51 generalized anxiety disorder GAD 51 Tumor Response 51 hemoglobin Hb 51 proctitis 51 ug ml 51 Prostate specific antigen 51 anthropometric measures 51 Subtype 51 hematological parameters 51 nmol 51 tertile 51 hypercholesterolaemia 51 paroxetine Paxil 51 MDQ 51 familial aggregation 51 mmol l 51 daytime alertness 51 hyperlipidemia hypertension 51 Ebstein anomaly 51 ropivacaine 51 variance ANOVA 51 analgesic medications 51 mmHg diastolic 51 inattention hyperactivity 51 plasma leptin 51 proBNP 51 Parnate 51 nonpsychiatric 51 hyperreflexia 51 neurocognitive function 51 abdominal pain flatulence 51 Ziprasidone 51 Pred Forte 51 LS BMD 51 internalizing disorders 51 8mg/kg 51 neutropenia febrile neutropenia 51 serum prostate 51 Epidemiologic Studies Depression 51 Outcome Measures 51 non affective psychosis 51 #,#,#,# [011] 51 Anxiety Scale 51 Claudication 51 function subscales 51 Sleep Disturbance 51 mm Hg diastolic 51 sociodemographic variables 51 intima media thickness 51 #.# df = 51 Wechsler Intelligence 51 myofascial pain syndrome 51 semistructured interview 51 Adjunctive 51 electrophysiologic 51 hemoglobin A1c HbA1c 51 comorbid psychiatric disorders 51 pyrexia mucositis sepsis febrile 51 proton MR spectroscopy 51 Pharmacologic 51 specific antigen PSA 51 Cystatin C 51 HLA DR4 51 insomnia dizziness 51 obstructive sleep 51 ACE Inhibitors 51 diabetes mellitus hypertension 51 Sjögren syndrome 51 HeFH 51 chest radiographs 51 Venous thromboembolism 51 Psychiatric Disorders 51 μg d 51 neurosensory 51 Subclinical 51 Angiographic 51 depressive disorders 51 Arch Intern Med 51 fractional shortening 51 MetS 51 Logistic regression 51 J Am Soc 51 % CI #.#-#.# [006] 51 Fracture Risk 51 Diabetic Neuropathy 51 ECOG PS 51 generalized anxiety disorder 51 Valvular 51 systolic hypertension 51 constipation OIC 51 Treatment Diabetic Retinopathy 51 fatigue headache nausea 51 undergoing radical cystectomy 51 prospective multicenter study 51 tissue oxygenation 51 Abdominal Pain 51 Endothelial function 51 posttransplant 51 Rheumatoid 51 postoperative AF 51 Follicular Lymphoma 51 Bipolar Mania 51 Assessment Scale 51 asthenia fatigue 51 r2 = 51 mu opioid 51 serum parathyroid hormone 51 Chronic Fatigue Syndrome CFS 51 hippocampal atrophy 51 #:#-# [031] 51 QVAR R 51 multi infarct dementia 51 FDG-PET/CT 51 MS DRG 51 PsA 51 lower extremity amputation 51 puerperal psychosis 51 prespecified secondary 51 depression suicidal ideation 51 FSFI 51 allergic rhinitis AR 51 Myocardial 51 #,#-# [008] 51 albumin excretion 51 MS DRGs 51 et al #b 51 Somnolence 51 adenotonsillectomy 51 neuroleptics 51 TMS Therapy 51 microgram kg 51 J Clin 51 thiopurine 51 CI = 51 Thal Dex 51 Methylphenidate 51 glomerular filtration 51 Atomoxetine 51 PEPI 51 paresthesia 51 ng dL 51 Cognitive impairment 51 Multivariate analysis revealed 51 DSM IV Axis 51 β blocker 51 exhaled nitric oxide 51 thyrotropin 51 hepatic cirrhosis 51 APTIVUS r 51 menopausal symptom 51 N acetyl 51 chills fever headache 51 hematologic parameters 51 Predictors 51 Prognostic Value 51 ejection fractions 51 Prophylactic Treatment 51 meta regression 51 Mean Symptom Complex 51 SLEDAI 51 venlafaxine Effexor 51 Exacerbation 51 glycated hemoglobin levels 51 Nocturia 51 preoperatively 51 meta analytic review 51 procedural sedation 51 prognostic variables 51 CONCERTA ® 51 Pelvic Organ Prolapse 51 EDSS 51 dyslipidaemia 51 Δ 51 Hyperlipidemia 51 transient elastography 51 Diagnostic Criteria 51 left ventricular LV 51 confidence interval CI 51 Systemic Sclerosis 51 Functional Capacity 51 frequent awakenings 51 fructosamine 51 #.#mg/dL 51 Genant modified Sharp 51 Atopic Dermatitis 51 interpersonal psychotherapy IPT 51 gastro esophageal reflux 51 plasma folate 51 risperidone Risperdal 51 Peginterferon Alfa 2a 51 Autistic Disorder 51 Cognitive Function 51 pericardial effusion 51 underwent coronary angiography 51 death reinfarction 51 Ischemic 51 overt nephropathy 51 chills headache 51 fractional anisotropy 51 Stent thrombosis 51 rho = 51 Non Alcoholic Steatohepatitis 51 Evaluable 51 nanograms milliliter 51 tracheal intubation 51 mEq L 51 generalized tonic clonic seizures 51 symptomatic intracranial 51 alfuzosin 51 Neuropathic 51 androgen suppression 51 multivariate regression analysis 51 μg L 51 umol L 51 overnight polysomnography 51 nonadherence 51 overt hypothyroidism 51 nausea dizziness vomiting 51 glycated hemoglobin HbA1c 51 myelodysplastic myeloproliferative diseases 51 prucalopride 51 NSTEMI 51 serum concentrations 51 corticosteroid dose 50 cervicitis 50 neurocognitive impairment 50 ß blockers 50 serum lipid levels 50 System IPSS 50 dose Iluvien 50 shorter telomere length 50 Thrombolysis 50 hypertension diabetes mellitus 50 bivalirudin monotherapy 50 methotrexate monotherapy 50 cerebral infarctions 50 OGTT 50 RISPERDAL ® 50 Pearson correlation coefficients 50 arteritis 50 biochemical recurrence 50 Abstract P# [002] 50 J Nutr 50 Bioavailability 50 collagenous colitis 50 DSM IV diagnoses 50 preintervention 50 deoxy 50 BSIs 50 serum retinol 50 Hemodynamic 50 hepatorenal syndrome 50 immunodeficiencies