Related by context. All words. (Click for frequent words.) 76 cellular pathways 75 FGFs 72 cell signaling pathways 72 pathogenic mechanisms 72 genetic determinants 72 underlying molecular mechanisms 71 genetic polymorphisms 70 molecular underpinnings 70 cAMP signaling 70 tumor microenvironment 70 Wnt signaling pathway 70 causative genes 70 molecular biomarkers 70 Genetic variants 69 molecular determinants 69 molecular pathways 69 intracellular signaling pathways 69 epigenetic regulation 69 DNA methylation patterns 69 underlying pathophysiology 69 prostate carcinogenesis 69 tumor hypoxia 69 epigenetic changes 69 causal pathways 69 molecular abnormalities 69 biologic pathway 68 breast cancer metastasis 68 oncogenesis 68 EGFR pathway 68 physiologic mechanisms 68 genetic loci 68 biological pathways 68 vitamin D receptors 68 neuropsychiatric diseases 68 epigenetic mechanisms 67 Genetic variations 67 antibody mediated 67 innate immune responses 67 CB2 receptor 67 signaling cascades 67 neuroinflammatory 67 sortilin 67 pathophysiological mechanisms 67 biochemical mechanisms 67 γ secretase 67 ADAM# 67 biomarker identification 67 beta1 integrin 67 tumor suppressor protein 67 immunological mechanisms 67 Akt3 67 p#/CBP 67 neuronal signaling 67 protein misfolding diseases 67 PI3K AKT 66 histone deacetylases 66 COX enzymes 66 kidney urologic 66 lipoprotein metabolism 66 beta defensins 66 hedgehog pathway 66 ADME properties 66 prognostic biomarkers 66 bile acid metabolism 66 intracellular bacteria 66 FSH receptor 66 molecular mechanisms underlying 66 PPARγ 66 virulence genes 66 diagnostic biomarkers 66 podocyte 66 AT1R 66 A3 adenosine receptor 66 intracellular pathways 66 metabolic enzymes 66 protein tyrosine phosphatases 66 TXNIP 66 MAPK pathway 66 synovial cells 66 predictive biomarkers 66 hedgehog signaling 66 Alpha synuclein 66 bone metabolism 66 tumor metastasis 66 inhibit angiogenesis 66 TRAIL induced apoptosis 66 Wnt pathway 66 ACAT2 66 p# pathway 66 proteins misfold 66 CaM kinase II 66 IGF IR 66 cathepsins 66 COX2 66 physiological mechanisms 66 serine proteases 66 Wnts 66 apoptotic pathway 65 galectins 65 Treg cell 65 hypothalamic pituitary adrenal axis 65 proNGF 65 cypin 65 anti angiogenic drugs 65 Ets2 65 p# activation 65 molecular subtypes 65 cholesterol metabolism 65 genetic susceptibilities 65 gene polymorphisms 65 TGF beta pathway 65 neurotrophic 65 prognostic markers 65 drug metabolizing enzymes 65 Cathepsin B 65 TGF b 65 fibrotic disease 65 HCV replication 65 tumor subtypes 65 susceptibility loci 65 receptor subtypes 65 cellular signaling pathways 65 intracellular signaling 65 validate biomarkers 65 micro RNAs 65 etiologic 65 NF kB pathway 65 epigenetically 65 primary cilia 65 atherogenesis 65 FOXO3a 65 PDGF receptor 65 chromatin structure 65 PIK3CA 65 fibrocytes 65 neuronal plasticity 65 pathophysiological 65 TLE3 65 inhibit enzymes 65 blood coagulation disorders 65 chromosome aberrations 65 kinase inhibition 65 bacterial virulence 65 PARP inhibition 65 methylation patterns 65 SIRT1 gene 65 genetic variants associated 65 interleukins 65 biochemical pathways 65 inhibiting enzymes 65 selective inhibition 65 HIF 1α 65 preclinically 65 angiogenesis inhibition 65 neuronal nicotinic receptors NNRs 65 pharmacodynamic markers 65 HSF1 65 vascular endothelial 65 diagnostic biomarker 65 PPARg 65 plasma kallikrein 64 PI3K Akt 64 causal variants 64 TMEM#B 64 p# MAPK 64 neuroinflammation 64 neuromuscular junction 64 renal fibrosis 64 histone modifications 64 immunoregulatory 64 Smac mimetics 64 glial tumors 64 Pseudomonas aeruginosa infections 64 immunomodulatory effects 64 prognostic indicators 64 Notch signaling 64 hypoxic tumors 64 DARPP 64 protein misfolding 64 phenotypic expression 64 intracellular proteins 64 neurotransmitter receptors 64 γδ T cells 64 EBV infection 64 EGF receptor 64 sirtuin activators 64 protein tyrosine kinase 64 airway remodeling 64 environmental toxicants 64 Apobec3 64 anticancer therapeutics 64 CYT# potent vascular disrupting 64 activin 64 SIRT3 64 receptor inhibitor 64 chromosomal regions 64 cardioprotective effects 64 oxysterols 64 IDH1 mutations 64 CagA 64 non coding RNA 64 differential gene expression 64 peptide antigens 64 neuronal dysfunction 64 arterial calcification 64 adaptive immunity 64 Src kinase 64 xenobiotic 64 allergic inflammation 64 chitinase 64 synapse formation 64 Symadex 64 APOE genotype 64 epigenetic alterations 64 endophenotypes 64 epigenetic markers 64 IGFBP2 64 metabolomic profiling 64 Fc receptor 64 clusterin 64 SSc 64 mucosal immunity 64 Stat5 64 cardiometabolic disorders 64 beta adrenergic receptors 64 fatty acid synthase 64 PKM2 64 gene rearrangements 64 colorectal carcinogenesis 64 neuropsychiatric disorders 64 pathogenetic 64 Protein Kinase C 64 airway hyperresponsiveness 64 FGFR1 64 genomic alterations 64 lipid synthesis 64 alpha synuclein gene 64 antitumor immunity 64 PKC alpha 64 myelofibrosis polycythemia vera 64 infectious prion proteins 64 subcellular compartments 64 prognostically 64 myogenesis 64 apoE 64 druggable targets 64 myeloproliferative diseases 63 Smad3 63 androgen signaling 63 PKCi 63 neuroligins 63 eicosanoids 63 JAK2 enzyme 63 TRP channels 63 DNA methyltransferases 63 Genetic predisposition 63 microRNA molecules 63 Clusterin 63 pharmacodynamic biomarkers 63 ARF1 63 ERK pathway 63 LRP5 63 circadian clock genes 63 p# mutations 63 cell signaling pathway 63 tau tangles 63 serotonin receptor 63 GRP# 63 LIS1 63 amygdala neurons 63 pharmacogenetic test 63 apoE4 63 neurexins 63 chemokine receptors 63 dopamine neuron 63 vimentin 63 proto oncogene 63 JAK STAT pathway 63 hereditary predisposition 63 EGFR inhibition 63 TTR amyloidosis 63 autoantigen 63 alpha synuclein protein 63 Wnt proteins 63 fibrate drugs 63 JAK inhibitors 63 MAP kinases 63 Darapladib 63 immune dysregulation 63 Akt activation 63 immuno modulatory 63 amyloid beta plaques 63 epithelial tissues 63 pleiotropic effects 63 synaptogenesis 63 cellular organelles 63 enzymatic pathways 63 pre malignant lesions 63 antiproliferative effects 63 antiangiogenic 63 Li Fraumeni 63 neuro protective 63 MetAP2 63 immune modulating 63 pathophysiologic mechanisms 63 #ß HSD1 63 amyloid plaque formation 63 epithelial barrier 63 upregulating 63 genetic underpinnings 63 mitochondrial toxicity 63 glutamate receptors 63 epigenetic modification 63 protein conformation 63 intracellular signal transduction 63 miRNA expression 63 adult neurogenesis 63 eTag assays 63 LRRK2 gene 63 genetic aberrations 63 familial clustering 63 carbohydrate polymers 63 microglial cells 63 endogenous ligands 63 neurobiological basis 63 NF kB signaling 63 STAT4 63 Notch pathway 63 cardio metabolic diseases 63 noncoding RNAs 63 Androgen receptor 63 signaling pathways 63 epithelial tumors 63 epigenetic therapies 63 myeloproliferative disorders 63 transcriptional activation 63 SH2 B 63 AhR 63 neurobiological mechanisms 63 VEGF expression 63 cytolytic 63 gene loci 63 ORMDL3 63 selectively inhibited 63 GBA mutations 63 intestinal microbiota 63 Pim kinases 63 sphingolipids 63 VEGF receptor 63 telomerase inhibitor 63 lung epithelium 63 etiologic factors 63 breast cancer subtypes 63 5 hydroxymethylcytosine 63 protein kinase C 63 miR #a [001] 63 amyloidogenic 63 Six3 63 ADAMTS# 63 Gleevec inhibits 63 sporadic ALS 63 nAChRs 63 mitogen activated protein kinases 63 Transcription factors 63 cardiac fibrosis 63 validating biomarkers 63 immunological responses 63 KRAS oncogene 63 biomarkers 63 TRIM5a 63 PI3K/mTOR 63 biochemical signaling pathways 63 molecular pathway 63 chemoresistance 63 Matthew Meyerson 63 STK# [002] 63 NKG2D 63 leukotriene pathway 63 K ras mutations 63 TGFBR1 * 6A 63 PTEN protein 63 alpha#beta# 63 genomic biomarkers 63 GSK3B 63 molecularly targeted therapies 63 lipid metabolism 63 serum antibodies 63 TLR antagonists 63 osteoclast formation 62 susceptibility genes 62 motor neuron degeneration 62 ERK signaling 62 organogenesis 62 sGC 62 androgen receptor AR 62 n cofilin 62 LSD1 62 enterotypes 62 autism susceptibility genes 62 galectin 62 biosynthetic pathways 62 genetic locus 62 small molecule activators 62 virulence determinants 62 stratifying patients 62 identify protein biomarkers 62 cytoprotective 62 FTIs 62 casein kinase 62 Epstein Barr Virus EBV 62 ciliopathies 62 melanocortin receptors 62 pharmacologic approaches 62 chromosome #p#.# 62 mitochondrial dysfunction 62 CXCR7 62 neuronal stem cells 62 MMP inhibitors 62 muscular dystrophies 62 somatic mutations 62 sphingolipid 62 ABCB1 62 MAP kinase 62 myelin repair 62 Notch receptors 62 selective modulator 62 Marc Weisskopf 62 granzyme B 62 inhibit viral replication 62 calpain 62 mTOR mammalian target 62 fusion enhancers 62 calcineurin 62 apelin 62 RIP1 kinase 62 molecular biomarker 62 NKT cells 62 pleiotropic 62 dendritic spine 62 genomic variation 62 antiangiogenic therapy 62 hepatic stellate cells 62 Kv#.# 62 monogenic 62 sarcosine 62 transcriptional regulation 62 Phylomer ® 62 melatonin receptor 62 metastatic lymph nodes 62 hormone angiotensin II 62 potentially modifiable 62 cMET 62 EphA2 62 GATA3 62 metabolic alterations 62 potent inhibitors 62 Th2 immune 62 TCF#L# 62 NFTs 62 sirtuin enzymes 62 CNPs 62 cardiolipin 62 Smac mimetic 62 excitotoxicity 62 deacetylase inhibitors 62 neural tissues 62 antiapoptotic 62 GSK3 62 adipokines 62 prognostic indicator 62 synaptic function 62 phenotypic differences 62 genotype phenotype 62 glucocorticoid receptor 62 MAP kinase pathway 62 oncogenic signaling 62 engineered RAP peptides 62 GCN2 62 proliferative disorders 62 MT1 MMP 62 MEF2D 62 inhibitory neurotransmitters 62 intercellular signaling 62 amyloid formation 62 obesity insulin resistance 62 neuro degenerative disorders 62 humanin 62 multiple sclerosis psoriasis 62 axon guidance 62 aberrant activation 62 antisense inhibitors 62 TRPV1 receptors 62 mechanistic insight 62 NADPH oxidase 62 E#F# 62 therapeutic monoclonal antibody 62 SLC#A# [002] 62 neural degeneration 62 Dysregulation 62 uPAR 62 morphogen 62 EGF receptors 62 MIF protein 62 neurobiological underpinnings 62 VHL gene 62 CYP#E# 62 Fibroblast Growth Factor Receptor 62 ubiquitin ligases 62 Hedgehog signaling 62 abnormal glucose metabolism 62 amyloid proteins 62 neuronal differentiation 62 RANKL 62 estrogen metabolism 62 N Myc 62 inflammatory cytokine 62 NS4B 62 EphB2 62 invadopodia 62 nonhuman primate model 62 secretory pathway 62 resolvins 62 hedgehog signaling pathway 62 NF kappaB pathway 62 INF2 62 arginase 62 HER2 expression 62 gene expression patterns 62 EGFR mutation status 62 Rap1 62 branching morphogenesis 62 lipid mediators 62 CaR 62 regulates gene expression 62 adhesion proteins 62 IKK2 62 histone modification 62 molecular pathogenesis 62 NPD1 62 glycolipids 62 neurite outgrowth 62 pathogen interactions 62 commensal bacteria 62 mechanistic studies 62 plasma lipid 62 Angiotensin converting enzyme 62 ALK inhibitors 62 coagulation cascade 62 immunotherapeutic approaches 62 endogenous cannabinoids 62 mGluR5 antagonist 62 beta globin gene 62 neuroregenerative 62 PTEN mutations 62 gastro intestinal inflammation 62 Curaxin 62 HMG CoA reductase 62 immunostimulatory effects 62 chemosensitivity 62 ZNF# 62 epigenetic modifications 62 CHD7 62 c MET 62 LRP1 62 effector function 62 prognostic marker 62 myopathies 62 protein homeostasis 62 amyloid deposition 62 Francisella 62 anti androgens 62 ADDLs 62 Dr. Bezprozvanny 62 PTPN# 62 Id1 62 inhibit metastasis 62 podocytes 62 tubulin inhibitor 62 immunotoxins 62 GABA neurotransmitter 62 chromatin modifications 62 transcriptional machinery 62 C. pneumoniae 62 carcinoid 62 tyrosine phosphorylation 62 Brodmann Area 62 SOD1 62 activated microglia 62 intracellular pathogens 62 amyloid toxicity 62 Micro RNAs 61 proliferative diseases 61 mutant proteins 61 neurotransmitter receptor 61 HOX genes 61 colonic mucosa 61 bacterial enzyme 61 oncoprotein 61 chromatin remodeling 61 diabetic kidney 61 BCL6 gene 61 IFRD1 61 Genetic mutation 61 microbiomes 61 Cryptococcus neoformans 61 metabonomics 61 mesenchymal cell 61 Tasigna prolongs 61 FGFR2 61 ERK1 2 61 amyloid protein plaques 61 orexin receptors 61 influenza neuraminidase 61 Dr. Pasinetti 61 inherited predisposition 61 Membrane proteins 61 heritable disorders 61 transgenic mouse models 61 CDK inhibitors 61 epigenomic 61 elastase 61 RNAi therapeutic targeting 61 TGF ß 61 carbohydrate metabolism 61 GABA receptor 61 retinoid X 61 GPCR targets 61 mitochondrial mutations 61 morphogens 61 platelet activation 61 Th2 cytokines 61 amyloid cascade 61 PI3K pathway 61 Hp2 2 61 pathological hallmark 61 neurosteroid 61 SGK1 61 PGRN 61 hyperactivated 61 genetic biomarkers 61 mTOR signaling pathway 61 LDL receptor 61 costimulatory 61 CEACAM1 61 intracellular pathway 61 microRNA expression 61 ALV# 61 Mechanistic studies 61 tumor suppressor proteins 61 RUNX3 61 HDACs 61 clefting 61 GABAB receptors 61 Brd4 61 therapeutically useful 61 druggable target 61 previously uncharacterized 61 BCL#A 61 VIPR2 61 CCR3 61 microRNA biomarkers 61 modifier genes 61 Shh signaling 61 calcium homeostasis 61 metalloprotease 61 nongenetic 61 stem cell differentiation 61 pericytes 61 molecular signaling pathways 61 thromboembolic disease 61 familial pancreatic cancer 61 neural mechanisms 61 hematopoietic cells 61 Thyroid hormones 61 prodynorphin 61 neuroactive 61 JAK3 61 perilipin 61 epigenetic inheritance 61 Smurf1 61 immunoregulation 61 nongenetic factors 61 FUS protein 61 immunologic responses 61 serum biomarkers 61 eotaxin 61 Oxidative damage 61 metabolomic profiles 61 RKIP 61 c Abl 61 serotonin synthesis 61 hypermethylated 61 mitogen activated protein kinase 61 Squalamine 61 tau aggregates 61 #beta HSD 1 61 Skeletal muscle 61 KIAA# 61 mTOR inhibitors 61 mTOR pathway 61 SGLT2 inhibitors 61 mitochondrial disorders 61 endocrine tumors 61 APOL1 61 Inflammatory diseases 61 fibrogenesis 61 pharmacologic intervention 61 mGluR2 NAM 61 CaM kinase 61 MGd 61 neuropathologic 61 TLR8 61 cyclic adenosine monophosphate cAMP 61 mitochondrial fusion 61 S. maltophilia 61 c MYC 61 biochemical abnormalities 61 acetylcholine receptor 61 mycobacterial 61 tumor vascularization 61 cisplatin resistant 61 pathogenesis 61 neurotrophic factors 61 LXRs 61 statins cholesterol lowering 61 splice junctions 61 immuno inflammatory 61 lymphoid tumors 61 telomere dysfunction 61 murine models 61 neuro degenerative diseases 61 serine protease 61 MAPCs 61 C5aR 61 circadian genes 61 molecular mechanism 61 motor neuron diseases 61 PDE#A 61 HER2 positivity 61 thrombo embolic 61 micronuclei 61 ligases 61 histone acetylation 61 SCD1 61 antitumor effect 61 orofacial 61 monoamines 61 NFKB 61 Aviptadil 61 KLF4 61 endoplasmic reticulum stress 61 PAR1 61 cyclic AMP cAMP 61 posttranslational modifications 61 Wnt beta catenin 61 polyamines 61 fatty acid metabolism 61 splice variants 61 antitumor immune 61 Galectins 61 ATTR CM 61 intestinal microflora 61 VKORC1 61 ANGPTL4 61 FGFR3 61 pro angiogenic 61 susceptibility gene 61 multifactorial disease 61 ischemic tissues 61 p# biomarker 61 trans palmitoleate 61 thymidylate synthase 61 Tarvacin Anti Viral 61 PLX MS 61 Tony Wyss Coray 61 cathepsin K 61 ADPKD 61 neuronal function 61 OGG1 61 kinase pathway 61 micro RNA 61 lipid rafts 61 prognostic significance 61 CALHM1 61 osteoclast 61 treating neuropathic pain 61 GPR# receptor [002] 61 PKC isoforms 61 Mitochondrial dysfunction 61 ADVEXIN therapy 61 oxidant stress 61 GABA receptors 61 small molecule agonists 61 cellular metabolism 61 lipid homeostasis 61 downregulating 61 interstitium 61 osteopontin 61 IL#R 61 FLT3 61 serine threonine kinase 61 miR #b [002] 61 fusogen 61 RIP1 61 oncogenic transformation 61 haematopoietic 61 TNF receptors 61 mTOR inhibition 61 mTOR kinase 61 thymidylate synthase TS 61 renal carcinoma 61 neuro endocrine 61 squamous cell lung cancer 61 potent inducer 61 NOD mice 61 NNRs 61 developmental neurotoxicity 61 post transcriptional 61 lymphangiogenesis 61 immunomodulation 61 ipRGCs 61 potent anti angiogenic 61 breast endometrial 61 Cytotoxic T 61 gut microbiota 61 glutamate signaling 61 NLRP3 61 cannabinoid receptors 61 neuroprotective properties 61 coactivators 61 SETDB1 61 SE alleles 61 secreted protein 61 microglial 61 B7 H3 61 NF KB 61 clinicopathological 61 bioinformatic approaches 61 tumor subtype 61 regulating gene expression 61 neurotrophins 61 inhibiting COX 61 M.tb 61 aP2 61 glycogen metabolism 61 SMAD4 61 epigenomics 61 metabolic abnormalities 61 PTHrP 61 Wwox 61 kidney fibrosis 61 multisensory integration 61 tenascin C 61 SPINK1 61 ERK2 61 presymptomatic 61 metastatic neuroendocrine tumors 61 Notch receptor 61 PI 3K 61 FGF2 61 Cdc7 61 hepatic fibrosis 61 LRP6 61 Hox proteins 61 ABCA1 61 pancreatic islet 60 VEGF inhibitors 60 Genetic mutations 60 anti atherogenic 60 CDK8 60 anti fibrotic 60 stimulate neurogenesis 60 MYH9 60 previously undescribed 60 pre mRNA splicing 60 P. falciparum parasites 60 peroxisome 60 HIF 1alpha 60 prion infections 60 proteoglycan 60 PKC isozymes 60 DLX5 60 HDAC inhibition 60 NKX#.# 60 neuroendocrine cancers 60 prefrontal regions 60 Hh 60 uricase 60 4E BP1 60 neuronal circuits 60 Nedd4 60 STAT3 signaling 60 leukaemic stem cells 60 senescent cells 60 fatty acid biosynthesis 60 tau protein tangles 60 Cyclin E 60 molecular etiology 60 JAK2 60 chromosomal rearrangement 60 Gleevec resistant 60 ABL1 60 cytochromes P# 60 EGFR signaling 60 small molecule modulators 60 GPx 60 hormone aldosterone 60 siRNA compounds 60 gp# protein [002] 60 HER2 HER3 60 underlying vasculopathy 60 IDH mutations 60 c myc gene 60 de novo mutations 60 heterologous expression 60 Sjögren syndrome 60 ionizing irradiation 60 small molecule defensin 60 cytokine signaling 60 pharmacogenetic testing 60 HDAC3 60 opioid peptides 60 motor neurones 60 NPC#L# 60 p#INK#a 60 ependymomas 60 ERBB2 60 optimal dosing regimens 60 EGFR mutations 60 chemokine receptor 60 Molnar Szakacs 60 serologic tests 60 FTLD 60 RNA ribonucleic acid 60 myelomas 60 MGUS 60 prostate cancer CaP 60 chromosomal aberrations 60 Bryostatin 60 metabolic pathways 60 GnRH neurons 60 Rho GTPases 60 Induced pluripotent stem cells 60 M. pneumoniae 60 polycythemia vera PV 60 glucocorticoid receptors 60 mutant huntingtin protein 60 metabolomic 60 microvessels 60 chemopreventive agent 60 radiolabeled TM# 60 immunomodulatory properties 60 RANK ligand 60 lymphotoxin 60 gamma oscillations 60 pharmacodynamic PD 60 autoreactive T cells 60 inflammatory demyelinating 60 oxidized phospholipids 60 Amyloid Beta 60 XL# inhibits 60 synaptic transmission 60 PTP 1B 60 pulmonary metastasis 60 HER2 receptor 60 oxidized LDL 60 TGF β 60 ryanodine receptor 60 act synergistically 60 gastric carcinomas 60 microbial pathogenesis 60 microtubule dynamics 60 galanin 60 CD# expression [002] 60 CPT1c 60 leukocyte adhesion 60 Nod1 60 KineMarker TM 60 gene locus 60 histone methylation 60 AKT pathway 60 Htt 60 Stat3 60 diabetic microvascular complications 60 TTR gene 60 FGF signaling 60 antitumour 60 neuroprotective therapies 60 ConclusionThis 60 bNAbs 60 mammary stem cells 60 habenula 60 hormones secreted 60 analgesic effects 60 BMPR2 60 novel VDA molecule 60 p# inhibitor 60 oncoproteins 60 CCL5