Related by context. All words. (Click for frequent words.) 68 anticancer activity 64 endosomal release 64 effector functions 64 effector function 64 intracellular uptake 63 antitumor 63 biodistribution 63 neurite outgrowth 63 EphA2 63 vivo potency 62 HCV replication 62 selective inhibition 61 cyclic AMP cAMP 61 IL #p# 61 plasmin 61 binding affinity 61 Zysolin TM 61 IFN gamma 61 bioactivity 61 Anticalins R 61 oral bioavailability 60 mitotic kinesin 60 ERK1 2 60 ApoA1 60 Preclinical studies suggest 60 synthetic peptides 60 lipid particles 60 binding affinities 60 antitumoral 60 prostaglandin E2 PGE2 60 tumorigenicity 60 flavopiridol 60 immune stimulatory 60 cytoprotective 60 proteolysis 60 anionic backbone 60 TRAIL induced apoptosis 60 vitro cytotoxicity 60 Akt activation 60 tyrosine phosphorylation 60 HCV protease 60 splice variants 60 antitumor efficacy 60 drug metabolizing enzyme 60 synthase TS 60 histone acetylation 60 c MYC 59 deacetylation 59 immunostimulatory 59 ENMD # 59 PHD2 59 MAPK pathway 59 solubilizing 59 Fc receptor 59 microglial activation 59 cyclic adenosine monophosphate cAMP 59 transfected cells 59 neuroprotective properties 59 antiangiogenic 59 glucocorticoid receptor 59 Akt phosphorylation 59 proteins peptides 59 solubilization 59 lipidoid 59 proteinase 59 nanoparticle formulations 59 RNAi compounds 59 glycolipids 59 RNA synthesis 59 enzymatic activity 59 immune modulating 59 Abeta# 59 polypeptides 59 peptide antigens 59 proton pump 59 thymidylate synthase TS 59 cyclic guanosine monophosphate 59 intracellular 59 prostaglandin synthesis 59 antiapoptotic 59 pharmacodynamic markers 59 monomeric 59 inhibitory effects 59 insulin sensitizing 59 DiLA2 liposomes 58 acetylcholinesterase 58 FUS1 58 glycosylation profile 58 thyroid hormone receptor 58 anti amnesic 58 HepG2 cells 58 cytolytic 58 novel peptide 58 Th2 cytokines 58 VEGF receptor 58 platelet adhesion 58 peptidic 58 antitumor effects 58 pharmacokinetic properties 58 VEGF expression 58 p# subunit 58 E#F# 58 UsiRNAs 58 BRAF kinase 58 Eg5 58 PTP 1B 58 induces apoptosis 58 p# activation 58 Anticalins ® 58 radiosensitivity 58 ERK signaling 58 superoxide dismutase 58 dihydrofolate reductase 58 combinability 58 antitumor effect 58 fatty acid biosynthesis 58 CENP E 58 protein CETP 58 trans splicing 57 stable nucleic acid 57 pro apoptotic 57 viral proteins 57 prostanoid 57 ESBA# 57 Vidofludimus 57 anti CD3 57 DepoVax 57 bacterial enzyme 57 c MET 57 enzyme inhibitor 57 spermidine 57 pro angiogenic 57 #ME# 57 collagen synthesis 57 activin 57 polyketides 57 RNA antagonist 57 Jhdm2a 57 sd rxRNA 57 induce apoptosis 57 #T# L1 57 anti proliferative 57 partial agonist 57 SGLT 57 small molecule agonists 57 pathophysiological effects 57 R baclofen 57 neuronal signaling 57 potently inhibit 57 transfection efficiency 57 transfection 57 FasL 57 osteoclast activity 57 pharmacodynamic profile 57 delta isoform 57 radiolabeled 57 asparagine 57 NEUGENE antisense 57 antiangiogenic activity 57 synaptic transmission 57 heparanase 57 isotypes 57 protease enzyme 57 sd rxRNA compounds 57 proteolytic degradation 57 5 HT4 receptor 57 PI3K/mTOR 57 fast skeletal troponin 57 glutamate receptors 57 DNA gyrase 57 mucociliary clearance 57 DiLA2 57 mTOR inhibitors 57 GLUT4 57 p# inhibitors 57 cytosolic 57 target enzyme thymidylate 57 TXNIP 57 inhibit replication 57 vascular endothelial cells 57 SIRT2 57 photostability 57 TAT2 57 HIF 1alpha 57 TNFa 57 subcellular compartments 57 ligand binding 57 ABCA1 57 HEK# cells 57 membrane permeability 57 histone deacetylase HDAC 57 JAK inhibitors 56 GSOs 56 transgene expression 56 protein albumin 56 FGFR 56 immune modulatory 56 CCR3 56 biologic therapeutics 56 cholecystokinin CCK 56 siRNA therapeutics 56 anticancer therapeutics 56 Hedgehog signaling 56 secretory pathway 56 serotonin synthesis 56 HCV protease inhibitors 56 Stat1 56 vWF 56 nanomolar 56 CEACAM1 56 replicon 56 HSP# inhibitors 56 humoral immune responses 56 aminobutyric acid 56 Fleximer 56 UsiRNA 56 TGF beta1 56 homodimers 56 bioavailability 56 oncoprotein 56 Factor VIIa 56 MEK ERK 56 dimerization 56 renal excretion 56 secretase 56 prodrugs 56 proapoptotic 56 amyloid β 56 adenoviral 56 calcitonin 56 IgG4 56 somatostatin 56 molecular biomarkers 56 liposomal formulation 56 recombinant protein 56 enzyme inhibitors 56 metalloenzymes 56 beta amyloid peptide 56 granzyme B 56 Cyclin E 56 norepinephrine reuptake inhibition 56 siRNA mediated 56 paxillin 56 transmembrane receptor 56 ß amyloid 56 AAG geldanamycin analog 56 cathepsins 56 humoral immunity 56 Pterostilbene 56 ERK2 56 P selectin 56 Membrane proteins 56 Zap CHO 56 antibody mediated 56 peroxidase 56 enzyme inhibition 56 radioprotective 56 TNF α 56 micronuclei 56 iNOS 56 physico chemical properties 56 DepoVax TM 56 IgG antibodies 56 keratinocyte 56 receptor mediated 56 Clusterin 56 xenograft models 56 cytotoxicity 56 neointimal proliferation 56 nanomolar range 56 fluid secretion 56 IGF1R 56 CRAC channel 56 extracellular dopamine 56 oncogenic transformation 56 methyltransferases 56 vascular endothelial 56 fusion protein 56 antisense oligonucleotides 56 humanized monoclonal antibodies 56 anti inflammatory cytokine 56 inhibit platelet aggregation 56 short hairpin RNAs 56 insulin sensitizing drug 56 glycogen synthesis 56 chromatin structure 56 Htt 56 Flt3 55 fibrinolytic 55 dsRNA 55 FKBP# 55 CYP3A 55 DXL# 55 histone deacetylase inhibitor 55 recombinant erythropoietin 55 peroxidation 55 circulating lymphocytes 55 #S subunit 55 platelet activation 55 NF kappaB activation 55 triacylglycerol 55 muscarinic 55 APOBEC3G 55 tolerogenic 55 antitumour 55 ACh 55 receptor activation 55 EGF receptor 55 favorable pharmacokinetic 55 SERMs 55 p#Kip# 55 viral genomes 55 hTERT 55 NPD1 55 adenosine diphosphate ADP 55 serine threonine kinase 55 chemotherapeutic drug 55 frataxin 55 mechanistic insights 55 immuno modulatory 55 antiproliferative activity 55 TLR8 55 transactivation 55 C5aR 55 adenosine receptor 55 fucose 55 immunostimulatory effects 55 MetAP2 55 orally dosed 55 PDE1 55 Fas ligand 55 immunological responses 55 LPA1 receptor 55 androgen receptor AR 55 anti mitotic 55 inhibitory activity 55 nanoparticulate 55 immunoregulatory 55 transcriptional activation 55 conventional siRNA molecules 55 elastase 55 pRb 55 inhibitory effect 55 siRNA molecules 55 redox active 55 tumor antigens 55 S1P receptor 55 inhibited tumor 55 splice variant 55 costimulatory 55 cleavable linker 55 systemically administered 55 potentiator 55 PGE2 55 rxRNA 55 lentiviral vectors 55 HCV replicon 55 Locked Nucleic Acid LNA 55 Protein Kinase C 55 siRNAs targeting 55 azelaic acid 55 Cdc7 55 innate immune responses 55 immunomodulatory effects 55 sirtuin enzymes 55 5 HT2C receptor 55 Liposomal 55 HbF 55 mitochondrial fusion 55 PI3K inhibitor 55 oligomer 55 angiogenesis inhibitor 55 virulence genes 55 FGFs 55 p# MAPK 55 liposome encapsulated 55 anti apoptotic 55 biofilm formation 55 immunotoxins 55 potentiating 55 cellular pathways 55 ENaC 55 estrogen receptor beta 55 naturally occurring amino acid 55 nucleotide analogs 55 integrase enzyme 55 PDGF receptor 55 PI3K inhibitors 55 cell signaling pathways 55 microsomes 55 potent antitumor 55 tyrosine kinase receptor 55 ATPase activity 55 TGF ß 55 LNP formulations 55 inhibit viral replication 55 Src kinases 55 rolipram 55 tau phosphorylation 55 vivo efficacy 55 protein p# 55 intestinal absorption 55 prodrug 55 gonadotrophin releasing hormone GnRH 55 CYC# 55 nanocarrier 55 LTB4 55 rhIL 7 55 eIF4E 55 lysosomal 55 cellulase 55 microsomal 55 targeting CD# 55 CCL5 55 RKIP 55 CHO cells 55 synovial fibroblasts 55 Aurora kinase 55 EGFR HER 55 racemic mixture 55 avidin 55 oxidative metabolism 55 Aβ 55 IFN alpha 55 cytotoxic 55 folate metabolism 55 sphingolipid 55 pharmacokinetic characteristics 55 pharmacokinetic interactions 55 HDAC 55 sd rxRNAs 55 RNAi pathway 54 vascular permeability 54 Symadex 54 abiotic stress tolerance 54 phagocytosis 54 autophagic 54 Treg cell 54 Notch1 54 mRNA expression 54 oral prodrug 54 siRNA knockdown 54 RNAi mediated 54 NS#/#A protease 54 membrane receptors 54 EZH2 54 EGFr 54 nanoparticle formulation 54 RNA sequences 54 Chk1 inhibitors 54 CCX# 54 ubiquinone 54 fulvestrant 54 Bcl xL 54 bioactive molecules 54 HuR 54 immunomodulation 54 Vpu 54 ciliary neurotrophic factor 54 HDAC inhibition 54 thioredoxin 54 cellular prion protein 54 Calcium absorption 54 glucagon secretion 54 plasma proteins 54 γ secretase 54 Hedgehog inhibitor 54 antitumor activity 54 intracellular signaling 54 hENT1 54 fatty acid oxidation 54 antiviral efficacy 54 CD8 T cell 54 Preclinical studies 54 receptor inhibitor 54 phosphorylated proteins 54 Factor Receptor 54 glycosylated 54 proteolytic cleavage 54 amikacin 54 miR #b [002] 54 virus AAV 54 GABAB receptors 54 GRP# 54 CG# [003] 54 morpholino 54 cytokine signaling 54 anti leukemic 54 ligand receptor 54 E1A 54 osteoinductive 54 Interferon alpha 54 ncRNAs 54 ribonuclease 54 hippocampal neurons 54 PDGFR 54 stem cell pluripotency 54 immune modulator 54 recombinant antibody 54 integrin receptors 54 Galectins 54 nucleoside analog 54 ascorbate 54 antisense inhibitor 54 Enhanze Technology 54 lipid nanoparticle 54 PEGPH# 54 mechanistic insight 54 pleiotropic effects 54 pharmacodynamic effects 54 antioxidant enzymes 54 post translational modifications 54 gp# protein [002] 54 M2e 54 liver hepatocytes 54 GABAA receptors 54 ERK pathway 54 phosphate binding 54 tumor vasculature 54 conjugates 54 Gleevec resistant 54 cationic lipid 54 prostaglandin E2 54 HDAC6 54 immunoreactivity 54 Fibroblast Growth Factor Receptor 54 chemical reactivity 54 incretin 54 pharmacodynamic properties 54 TMEM#B 54 phagocyte 54 siRNA binds 54 phosphatases 54 ApoA l 54 fatty acid metabolism 54 orally bioavailable 54 mda 7 54 DGAT1 54 glioblastoma cells 54 ApoB 54 potent antibacterial 54 VEGFR2 54 #HT#A 54 HER3 54 neutralizing antibody 54 noncoding RNA 54 GelSite R polymer 54 proteasome inhibitors 54 ZFNs 54 exosome 54 PKM2 54 dAbs 54 gastric acidity 54 interferon lambda 54 miR #a [001] 54 Dietary restriction 54 siRNA molecule 54 racemate 54 anti angiogenic agent 54 PI3 kinase 54 immunomodulator 54 tumor antigen 54 plasminogen 54 Amino acid 54 ErbB3 HER3 54 BioSilicon 54 S#P# 54 anti neoplastic 54 molecularly targeted 54 adenoviral vector 54 neuropilin 54 enzymatic pathways 54 milatuzumab 54 siRNA 54 neurotransmitter GABA 54 Adenosine 53 IGF 1R 53 IFNg 53 FAAH 53 CCL# 53 lipid nanoparticles 53 BAL# [002] 53 pharmacodynamic parameters 53 tumor specific antigen 53 antigenicity 53 partial agonists 53 polyethylene glycol PEG 53 lysate 53 macrophage activation 53 dsDNA 53 vidofludimus 53 oncoproteins 53 biotransformation 53 cytokines IL 53 tryptase 53 therapeutically relevant 53 sequence homology 53 Ii protein 53 AhR 53 mPGES 1 53 vasodilatation 53 subcutaneously injected 53 bleomycin 53 IRE1 53 polypeptide 53 Cyclosert 53 histone deacetylase inhibitors 53 intestinal mucosal 53 selective kinase inhibitor 53 adaptive immunity 53 K ras mutations 53 hsp# 53 serum PTH 53 busulfan 53 DNA demethylation 53 bile acid 53 Vitamin D2 53 c Src 53 RNA silencing 53 DHFR 53 rifamycins 53 allosteric mechanism 53 potent anticancer 53 hedgehog pathway 53 potent cytotoxic 53 cytostatic 53 GPR# [002] 53 HMG CoA reductase 53 inhibitory neurotransmitters 53 act synergistically 53 topoisomerase 53 cyclin dependent kinase inhibitor 53 ubiquinol 53 uPAR 53 NS4A 53 pharmacological chaperone 53 bactericidal 53 neurotransmission 53 STAT1 53 Phylomer 53 interferon γ 53 NADPH oxidase 53 viral antigens 53 physicochemical properties 53 lactate dehydrogenase 53 aqueous solubility 53 GAPDH 53 gastrointestinal motility 53 survivin 53 Panzem 53 pyrophosphate 53 drug metabolizing enzymes 53 liposomal 53 RAR beta 53 Sphingosine 1 53 neuroactive 53 antioxidant enzyme 53 Tubulin 53 synapse formation 53 proinflammatory mediators 53 neuronal function 53 humoral responses 53 cathepsin B 53 inhibit tumor 53 serotonin reuptake 53 vorinostat 53 CCR9 53 fatty acid synthesis 53 annexin V 53 LSD1 53 protein kinase C 53 poly ADP ribose polymerase 53 therapeutic monoclonal antibodies 53 humanized antibody 53 pharmacokinetic PK profile 53 protein synthesis 53 tubulin 53 nucleases 53 leukemic cells 53 lysosomal enzyme 53 Biolimus A9 53 glucocorticoid 53 mTORC1 53 protein kinase inhibitor 53 untranslated regions 53 endogenous ligands 53 enzymatic pathway 53 relaxivity 53 preclinically 53 active metabolite 53 NSCLC tumors 53 TNFR 53 HER2 receptor 53 microRNA molecules 53 gamma tocotrienol 53 Curaxin 53 GelVac TM 53 azacytidine 53 zoledronate 53 apoptotic 53 Etoposide 53 miRNA expression 53 Belerofon 53 siRNA duplexes 53 BiTE 53 viral antigen 53 siRNA delivery 53 lipid synthesis 53 liposomes 53 apoptosis inducing 53 costimulation 53 VEGFb 53 p#/CBP 53 eosinophil count 53 telomerase activity 53 antioxidative 53 buccal delivery 53 intracellular protein 53 shRNA 53 Posiphen 53 peroxisomes 53 peptides 53 bacterial toxins 53 gamma secretase 53 neuronal dysfunction 53 radical scavenging 53 HCV NS3 protease 53 STAT3 activation 53 species ROS 53 biotinylated 53 clusterin 53 Nedd4 53 UCP2 53 replicase 53 mitochondrial function 53 miR #a [002] 53 non coding RNA 53 malate 53 systemic toxicity 53 synaptogenesis 53 outer membrane proteins 53 antibody fragment 53 LY# [003] 53 opioid peptides 53 gene rearrangements 53 RLY# 53 molecule 53 pharmacokinetic profiles 53 include ketoconazole acetaminophen 53 BAL# [001] 53 gene silencing 53 antithrombotic 53 commensal bacteria 53 IAP inhibitor 52 Thiovir 52 FGF receptor 52 forskolin 52 N Myc 52 exendin 4 52 lung fibroblasts 52 TNFα 52 HER2 receptors 52 MCF7 cells 52 cofilin 52 salmon calcitonin 52 EZN 52 caspase inhibitors 52 HSF1 52 A3 adenosine receptor 52 transcriptional regulation 52 microglial 52 hypoxia inducible factor 52 IMPDH 52 DNA methyltransferases 52 HIF 1a 52 nanomedicines 52 IgG1 antibodies 52 lysozyme 52 human hepatocytes 52 nucleic acid lipid 52 AT1R 52 VIPR2 52 E3 ligase 52 CLORETAZINE TM VNP#M 52 AVI NEUGENE 52 PIP3 52 heparan sulfate 52 MTP inhibitor 52 dose dependently 52 urease 52 mucin 52 HDAC inhibitors 52 pharmacokinetic profile 52 ISF# 52 CCR2 52 VDAs 52 cyclin B1 52 NanoEmulsion 52 suppressor gene 52 glioma cells 52 mGluR5 antagonist 52 ghrelin receptor 52 telomerase activation 52 cobalamin 52 vascular disrupting agents 52 serum calcium levels 52 cellular metabolism 52 p#INK#a 52 endosomal 52 Aptamer 52 CLA isomers 52 Cytotoxic T 52 innate immune 52 Kinoid 52 pegylated 52 tRNA synthetase 52 nutlin 52 MMP9 52 urinary glucose excretion 52 inactivating 52 cellular signaling pathways 52 neutrophil recruitment 52 cyclophilin D 52 NEUGENE 52 Transferrin 52 gastrointestinal absorption 52 uroguanylin 52 bispecific antibody 52 immunogenic 52 CYP #A# 52 #beta estradiol 52 antiviral antibacterial 52 dopamine reuptake 52 mutant proteins 52 tumor cells 52 PKCi 52 ectopic expression 52 molecules 52 exon skipping 52 geldanamycin 52 camptothecin 52 proinflammatory cytokine 52 mutant huntingtin 52 cytochrome P# #A# 52 contractile function 52 DNMT1 52 teriflunomide 52 Stat5 52 leukemic cell 52 Hsp# inhibitors 52 siRNA therapeutic 52 adult neurogenesis 52 ceramide 52 G Protein Coupled 52 anti angiogenic 52 nicotinic acetylcholine receptor 52 parathyroid hormone PTH 52 histone deacetylases 52 generation Hsp# inhibitors 52 postprandial glycemia 52 myocardial reperfusion 52 potent inhibitor 52 TGFβ 52 Wnts 52 IL 1beta 52 neuroinflammatory 52 delafloxacin 52 immunologically 52 warfarin erythromycin 52 phosphorylated Akt 52 glycoprotein 52 Aurora Kinase 52 intracellular signaling pathways 52 Nod1 52 Tyrima 52 E cadherin expression 52 macromolecules 52 Supplementary Fig 52 Microtubule 52 GHRH 52 leukotriene B4 52 dosing frequency 52 nicotinic 52 constitutively 52 mAbs 52 CD# ligand 52 MEK1 52 pyrimidines 52 cytotoxic effects 52 E. faecalis 52 protein kinases 52 AAV vector 52 co stimulatory molecules 52 interleukin IL -6 52 nucleosides 52 histone deacetylase 52 cytotoxic compounds 52 PEGylated 52 antisense molecules 52 JAK3 52 vivo 52 membrane fusion 52 FGF2 52 uPA 52 CYT# 52 biosynthetic enzymes 52 allergic inflammation 52 pharmacodynamic PD 52 prostaglandin E 52 synthases 52 ubiquitination 52 estrogen receptor alpha 52 EpCAM 52 VLPs 52 bronchodilation 52 NF kappaB 52 piperine 52 phage display 52 metabolite concentrations 52 collagen degradation 52 electrophysiological properties 52 octreotide acetate 52 DsiRNA 52 β amyloid 52 lowers blood glucose 52 Skp2 52 tumor hypoxia 52 apoptotic pathway 52 antidepressant efficacy 52 inhibit metastasis 52 serum concentrations 52 antisense 52 TGF β 52 adhesion molecule 52 SERCA2a 52 systemic absorption 52 preclinical models 52 tricyclic 52 lymphoid cells 52 glycogen metabolism 52 taxol 52 analgesic effects 52 monoclonal 52 Smoothened 52 interferon IFN 52 SMaRT ™ 52 antibody reagents 52 chemokine receptor 52 potentiation 52 nucleolin 52 antisense RNA 52 plasmid DNA 52 phytoene 52 gp# [002] 52 exocrine pancreas 52 airway hydration 52 methylated DNA 52 RONDEL TM 52 antiinflammatory 52 recombinant antibodies 52 oxidative stress markers 52 RANKL 52 intestinal permeability 52 immunomodulatory 52 short interfering RNA 52 fusion enhancers 52 stimulate insulin secretion 52 Immunohistochemical analysis 52 transcriptional machinery 52 DNA plasmids 52 HSP# 52 PI3K 51 homologous recombination 51 neural cells 51 ribozymes 51 nuclease 51 myeloma cells 51 catalytically active 51 CDK inhibitor 51 immunogens 51 RANTES 51 pleiotropic 51 peptide 51 CA4P 51 methylation patterns 51 endoxifen 51 cell adhesion molecules 51 phenotypic expression 51 sulindac 51 antiproliferative effects 51 systemic bioavailability 51 hypericin 51 DLC1 51 STAT3 51 small interfering RNA 51 NF kB pathway 51 matrix metalloproteinases 51 SRT# [003] 51 androgen receptor