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(Click for frequent words.) 76 genetic loci 72 pathogenic mechanisms 71 etiologic 69 underlying pathophysiology 69 aetiology 69 neuropsychiatric diseases 69 underlying molecular mechanisms 68 APOE genotype 68 neurobiological mechanisms 68 neurobiological basis 68 pathophysiological 68 pathophysiological mechanisms 68 DNA methylation patterns 68 genetic polymorphisms 67 missense mutations 67 neuroanatomical 67 splice variants 67 alexithymia 67 chronicity 66 SLC#A# [002] 66 clinicopathological 66 prognostic markers 66 molecular subtypes 66 susceptibility loci 66 chromosome #p#.# 66 etiological 66 neuropathologic 66 aetiological 66 euthymic patients 66 mGluR2 NAM 66 molecular mechanisms underlying 66 familial aggregation 66 neuronal dysfunction 66 neural substrates 65 susceptibility genes 65 genotype phenotype 65 phenotypic expression 65 prognostic indicators 65 pathophysiologic 65 pharmacologic intervention 65 nosology 65 causative genes 65 clinicopathologic 65 comorbid disorders 65 functional polymorphism 65 CNTNAP2 64 paraneoplastic 64 molecular determinants 64 nongenetic 64 neuroimaging studies 64 genetic determinants 64 pharmacodynamic biomarkers 64 differential gene expression 64 breast cancer subtypes 64 methylation patterns 64 mechanistic studies 64 FGFs 64 susceptibility gene 64 susceptibility locus 64 PITX2 64 MAPK pathway 64 neural correlates 64 glial tumors 64 biopsychosocial 64 myeloproliferative 64 dysbindin 64 biologic pathways 64 molecular abnormalities 64 amyloid cascade 64 premorbid 64 genomic alterations 64 modifier genes 64 genetic modifiers 64 biochemical abnormalities 64 PDE# inhibitors 64 A3 adenosine receptor 64 extramedullary 64 genomewide 64 Clusterin 64 cognitive affective 64 kinase inhibition 63 molecular biomarkers 63 gene polymorphisms 63 epigenetic mechanisms 63 genetic locus 63 subclinical atherosclerosis 63 chromosomal regions 63 genetic polymorphism 63 epigenetic regulation 63 diagnostic biomarker 63 de novo mutations 63 circadian genes 63 cAMP signaling 63 comorbid anxiety 63 chromosomal anomalies 63 sporadic ALS 63 pathophysiologic mechanisms 63 tumorigenicity 63 monozygotic twins 63 epistasis 63 pharmacodynamic markers 63 gene loci 63 Brodmann Area 63 activating mutation 63 prognostic biomarker 63 familial clustering 63 prostate carcinogenesis 63 causal pathways 63 pathogenetic mechanisms 63 distinct subtypes 63 Genetic variations 63 tyrosine phosphorylation 63 somatic mutations 63 prognostic marker 63 phenotypic variation 63 pleiotropy 63 myeloproliferative diseases 63 NOD mouse 63 affective psychosis 62 PTPN# 62 gene locus 62 genomic variation 62 monoclonal gammopathy 62 etiology 62 neurodevelopmental disorders 62 prefrontal cortical 62 psychopathology 62 neuropsychological impairments 62 prognostic biomarkers 62 monogenic 62 axon guidance 62 RRM1 62 SNP rs# [002] 62 #q#.# [002] 62 germline mutations 62 protein tyrosine phosphatase 62 autism susceptibility genes 62 aMCI precursor 62 oncogenesis 62 miRNA expression 62 sequence homology 62 K ras mutations 62 Kraepelin 62 KIAA# 62 microRNA biomarkers 62 psychobiological 62 myeloproliferative disorders 62 Protein Kinase C 62 molecular signaling pathways 62 lipoprotein metabolism 62 adjuvant systemic 62 ataxias 62 Genetic variants 62 presymptomatic 62 nicotinic receptor 62 neurobiological underpinnings 62 IGFBP2 62 endogenous ligands 62 N glycan 62 cerebellar vermis 62 histone methylation 62 synaptic function 62 mutational status 62 genetic variants associated 62 serum biomarkers 62 gastric carcinoma 62 prognostic significance 62 evolutionarily conserved 62 convergent validity 62 modulatory 62 autoantigen 62 phenotypes 62 GABAB receptors 62 PCA3 gene 62 neuropsychiatric disorders 62 IFRD1 62 posttranslational modifications 62 histone modifications 62 Dysregulation 62 transgenic mouse models 62 mechanistic insights 61 polygenic 61 clinicopathological features 61 microsatellite instability 61 SMAD4 61 catechol O methyltransferase 61 Alzheimer disease cognitive impairment 61 pulvinar 61 microRNA expression 61 chromosome #p# [002] 61 nondemented 61 somatoform disorders 61 causative mutations 61 DARPP 61 ZNF# 61 prospective longitudinal 61 metaplasia 61 epigenetic therapeutics 61 adipokines 61 etiologic factors 61 debilitating neurodegenerative disorder 61 protein conformation 61 orthologs 61 thyrotropin 61 pathological hallmarks 61 neuropsychological functioning 61 neuropsychiatric disorder 61 genetic biomarkers 61 abnormal p# 61 5 hydroxymethylcytosine 61 emotional dysregulation 61 potentially modifiable 61 metabolomic profiles 61 perilipin 61 maturational 61 #q# [001] 61 Hutchinson Gilford progeria 61 thrombophilia 61 CagA 61 GABAergic interneurons 61 differentially expressed genes 61 beta1 integrin 61 immunodeficiencies 61 genomic biomarker 61 transmembrane protein 61 intracellular signal transduction 61 protein tyrosine phosphatases 61 #q#.# [001] 61 apoE 61 transcriptional regulation 61 GPC5 61 clefting 61 MECP2 gene 61 beta secretase inhibitors 61 rs# [004] 61 obstructive coronary artery 61 splice variant 61 neuroligins 61 PPARγ 61 causal variants 61 allelic variation 61 Lenzenweger 61 histone deacetylases 61 quantitative trait loci 61 cell adhesion molecule 61 FGFR2 61 ontogenetic 61 drug metabolizing enzymes 61 pathological hallmark 61 renal fibrosis 61 chromosome #q# [002] 61 androgen receptor AR 61 syndromal 61 splice junctions 61 PARP inhibition 61 causal pathway 61 ligand receptor 61 immunoregulatory 61 VKORC1 61 hippocampal function 61 genetic aberrations 61 engineered RAP peptides 61 bioinformatic approaches 61 psychiatric comorbidity 61 TGFBR1 * 6A 61 tumor subtypes 61 neuropathological 61 explanatory variables 61 mediated inhibition 60 Leydig cell 60 epilepsy Parkinson disease 60 TCF#L# 60 inherited retinal 60 Fas ligand 60 myelofibrosis polycythemia vera 60 essential thrombocythemia 60 ERK signaling 60 supratentorial 60 alpha7 60 metabolomic 60 genes predisposing 60 glycolipid 60 HG PIN 60 comorbid psychiatric disorders 60 TCF#L# gene 60 non pharmacological interventions 60 neuroendocrine 60 Anticalins R 60 dysbindin gene 60 prostate cancer CaP 60 inactivating mutations 60 FLT3 60 KIBRA 60 selective antagonists 60 Predisposition 60 causative gene 60 lysophosphatidic acid LPA 60 PDGF receptor 60 Karayiorgou 60 schizotypal 60 EML4 ALK 60 #q# deletion 60 AKT1 60 muscular dystrophies 60 non coding RNA 60 #p#.# [002] 60 neoplastic 60 neurofibrillary 60 SNP rs# [001] 60 gastric carcinomas 60 TMEM#B 60 predictive biomarkers 60 ABCB1 60 schizophrenia CIAS 60 pathogenetic 60 TGF b 60 steroidogenic 60 pleiotropic effects 60 bile acid metabolism 60 Fc gamma receptor 60 PICALM 60 p# activation 60 mechanistic insight 60 neurocognitive impairment 60 #q#.# deletion syndrome 60 etiological factors 60 noncoding RNAs 60 substrate specificity 60 neural underpinnings 60 Mechanistic studies 60 virulence genes 60 biomarker 60 psychosocial variables 60 Wnt signaling pathway 60 posterior cingulate 60 Apolipoprotein E 60 HER pathway 60 neurobiological 60 CD1d 60 inhibitory receptor 60 sociodemographic variables 60 Heterogeneity 60 isotypes 60 APOE e4 60 protein tyrosine kinase 60 transcriptional regulators 60 prodromal 60 Logistic regression 60 mTOR inhibition 60 androgen signaling 60 NSCLC tumors 60 LRP5 60 pathophysiologic mechanism 60 ncRNA 60 miR #a [001] 60 biologies 60 inherited mutations 60 genome rearrangements 60 Haptoglobin 60 effector function 60 differentially expressed proteins 60 Aromatase 60 LIS1 60 Neurodegenerative diseases 60 electroencephalographic 60 TMPRSS2 ERG fusion 60 pathophysiological effects 60 serine protease 60 Bardet Biedl Syndrome 60 KLF4 60 HIF 1alpha 60 Symadex 60 bronchopulmonary dysplasia BPD 60 transcriptomics 60 transgenic mouse model 60 neuroregenerative 60 ankyrin repeat 60 P2X 60 MSH2 60 noncoding RNA 60 observable traits 60 homodimers 60 Hsp# inhibition 60 mPFC 60 enterotypes 60 mutational analysis 60 Multiple logistic regression 60 Genetic predisposition 60 androgen deficiency 60 DQB1 * 60 epigenetic modifications 60 pathophysiology 60 highly heritable 60 DNA methylation markers 60 rhIGFBP 3 60 MT1 MMP 60 QTL mapping 60 Janus kinase 60 immunohistochemical staining 60 chromosome #q#.# [001] 60 Smad3 60 FTLD 60 CHRNA5 60 ADAMTS# 59 1 diabetes T1D 59 protein kinase C 59 NOD2 59 immunotherapeutic approaches 59 immunohistochemical 59 electrophysiologic 59 Activating mutations 59 cellular pathways 59 cerebrospinal fluid biomarkers 59 covariate 59 Corgentin 59 VEGF receptor 59 tolerability pharmacokinetics 59 atherothrombotic 59 Phenotypic 59 nucleosome positioning 59 immunomodulation 59 molecular biomarker 59 childhood disintegrative disorder 59 CALHM1 59 PIGF 59 Angiotensin converting enzyme 59 predisposing factor 59 Oxidative damage 59 lymphoid tumors 59 neuroactive 59 mucinous 59 histone acetylation 59 Leydig cells 59 JAK3 59 lymphangiogenesis 59 LRRK2 mutation 59 5 HT2A 59 gastrointestinal dysfunction 59 Fibroblast Growth Factor Receptor 59 SSc 59 Cognitive impairment 59 interindividual differences 59 ccRCC 59 chromosomal rearrangement 59 preclinically 59 IPAH 59 bone marrow mesenchymal stem 59 hypermethylated 59 obesity insulin resistance 59 mGluR5 antagonist 59 IDH1 mutation 59 tumor necrosis 59 KRAS mutation status 59 IntroductionThe 59 Molnar Szakacs 59 chemosensitivity 59 homeobox gene 59 biologic pathway 59 COX2 59 Estrogen Receptor 59 amyloidogenic 59 NPHP 59 pleiotropic 59 ibudilast 59 lysosomal storage diseases 59 JAK inhibitors 59 comorbid psychiatric 59 carcinoembryonic antigen 59 epilepsies 59 neuroinflammatory 59 inherited predisposition 59 neuropsychological assessment 59 synaptogenesis 59 S. maltophilia 59 schizophreniform disorder 59 physiologic mechanisms 59 pharmacodynamic parameters 59 microdeletion 59 p# MAPK 59 sCJD 59 proband 59 adult neurogenesis 59 chemokine receptor 59 C#T [002] 59 laterality 59 affective psychoses 59 retinoid X 59 noncognitive 59 epigenetic alterations 59 cMET 59 CD# expression [002] 59 MYH9 59 lymphocyte activation 59 neurosensory 59 proteomic analysis 59 ABCB1 gene 59 VIPR2 59 TGFß 59 cognitive impairment associated 59 interferon γ 59 EGFR mutation status 59 NKG2D 59 Alleles 59 Brain derived neurotrophic 59 internalizing disorders 59 unmeasured confounding 59 Endothelial dysfunction 59 IL#R 59 galectin 59 progressive neurodegenerative disorder 59 rs# [002] 59 genetic syndromes 59 CDK inhibitors 59 epigenomics 59 Leukemias 59 epigenetic markers 59 Shortened telomeres 59 pathogenesis 59 metabolic abnormality 59 neuropsychological impairment 59 pharmacologic interventions 59 left ventricular diastolic 59 multisensory integration 59 sensory gating 59 enzymatic pathways 59 pre malignant lesions 59 haematopoietic 59 cerebellar 59 neurocognitive deficits 59 gene polymorphism 59 CYP#D# genotype 59 mGluR5 inhibition 59 inverse agonist 59 DEAR1 59 hepatocellular carcinomas 59 cathepsins 59 calcium calmodulin dependent 59 Eg5 59 epigenetic modification 59 neuropilin 59 downstream effectors 59 P#X# 59 biopsychosocial model 59 predictive biomarker 59 FDG PET imaging 59 MEF2A 59 behavioral disinhibition 59 sphingolipid 59 CYT# potent vascular disrupting 59 p# biomarker 59 selective inhibition 59 receptor subtypes 59 ciliopathies 59 telomere dysfunction 59 ATG#L# 59 circadian clock genes 59 MLL2 59 fibrotic disease 59 microbiomes 59 neuroimaging techniques 59 florbetaben 59 tRNA synthetases 59 childhood acute lymphoblastic 59 FGFR3 59 signaling cascades 59 logistic regression model 59 SLITRK1 59 paralogs 59 #beta HSD1 59 comorbid depression 59 FSH receptor 59 Prognostic factors 59 diagnostic biomarkers 59 BRAF V#E mutation 59 downstream effector 59 Brugada syndrome 59 predictive validity 59 motor neuron degeneration 59 underlying vasculopathy 59 p# mutations 59 metabolic dysfunction 59 autosomal 59 HER2 expression 59 antiproliferative effects 59 5 HTTLPR 59 spontaneous mutations 59 hamartomas 59 MGUS 59 Tasigna prolongs 59 subtype selective 59 neuroinflammation 59 promoter methylation 59 chromosome #p# [001] 59 EGFR HER2 59 HLA DRB1 59 allelic variants 59 xenobiotic 59 miRNAs miR 59 Posiphen 59 myopathies 59 GPCR targets 59 diabetes dyslipidemia 59 lung epithelium 59 protein ligand 59 Rap1 59 psychopathological symptoms 59 subthreshold 59 hypogonadotropic hypogonadism 59 Hurthle cell 59 ultrastructural 59 antidepressant efficacy 59 Lewy bodies DLB 59 GPR# [002] 59 #F FDG PET 59 Functional neuroimaging 59 BioMAP 59 selective agonists 59 STAT3 signaling 58 multigene 58 osteochondroma 58 prognostic indicator 58 somatization 58 stratifying patients 58 ORFs 58 airway hyperresponsiveness 58 murine models 58 metastatic lymph nodes 58 cDNA microarray 58 hormone receptor status 58 ADPKD 58 HOTAIR 58 Nod1 58 neurite outgrowth 58 penetrance 58 c myc gene 58 histological subtype 58 medial frontal cortex 58 metabolomic profiling 58 PTEN mutations 58 AT1R 58 TIMP 1 58 HbF 58 constitutively expressed 58 IL 7R 58 Morphological 58 transcriptional activation 58 multivariate Cox 58 epigenetically 58 KRAS mutations 58 p#/CBP 58 PON1 58 multivariate analyzes 58 metabolic abnormalities 58 etiologies 58 histologic subtypes 58 siRNA knockdown 58 Singh Manoux 58 CYP#C# gene 58 IgA deficiency 58 HGPS 58 histologic subtype 58 histone deacetylase HDAC 58 Treg cell 58 pharmacological approaches 58 dopamine hypothesis 58 neuronal nicotinic receptors NNRs 58 C5aR 58 heritability 58 autonomic dysfunction 58 neurocognitive dysfunction 58 CDH1 58 novel VDA molecule 58 hypothalamic pituitary adrenal axis 58 Sociodemographic 58 glucose homeostasis 58 γ secretase 58 pilocytic astrocytomas 58 neurotrophic 58 alpha synuclein gene 58 B7 H4 58 meta analytic 58 hypothalamic pituitary 58 TRAIL induced apoptosis 58 hematopoietic cancers 58 astrocytic 58 Borderline personality 58 somatostatin receptors 58 psychosocial functioning 58 K ras mutation 58 costimulatory 58 Neuroprotection 58 microdeletions 58 PC# cells 58 p# INK4a 58 cell signaling pathways 58 phenotypic differences 58 eIF 4E 58 antagomirs 58 neurexins 58 prostate carcinoma 58 small molecule activators 58 previously uncharacterized 58 #ß 58 seminomas 58 thyroid carcinoma 58 small molecule agonists 58 mitochondrial disorders 58 FBPase 58 serine threonine kinase 58 tumor histology 58 glucocorticoid receptors 58 tumor suppressor protein 58 agnosia 58 colorectal carcinogenesis 58 transcriptomic 58 HIF PH inhibitors 58 myocardial ischaemia 58 oncologic outcomes 58 molecular underpinnings 58 primate genomes 58 phospholipase A2 58 morphologic 58 poststroke depression 58 eTag assays 58 CaM kinase II 58 M. pneumoniae 58 angiographically 58 PITX2 methylation 58 primary hyperparathyroidism 58 Intervention Effectiveness CATIE 58 PGRN 58 QTLs 58 pediatric bipolar disorder 58 putative biomarkers 58 kidney urologic 58 #p#.# [001] 58 coexpression 58 Hypothalamic 58 plexiform 58 comorbidity 58 affective disorders 58 Parkinson Disease PD 58 C#Y 58 mda 7 58 heritable diseases 58 resolvins 58 ESR1 58 bilaterians 58 biomarkers 58 plasma pharmacokinetics 58 CYP#C# [002] 58 neurodevelopmental disorder 58 oligodendrogliomas 58 inflammatory demyelinating 58 prognostic variables 58 neuronal nitric oxide synthase 58 chromosomal alterations 58 IRAK1 58 protein ligand interactions 58 mGluR 58 glutamatergic 58 pro angiogenic 58 HER2 HER3 58 miRs 58 ERK1 2 58 gliosis 58 epithelial tumors 58 TACI Ig 58 GBA mutations 58 hyperplastic 58 Accurately identifying 58 clonogenic 58 neurochemistry 58 neuro endocrine 58 genomewide association study 58 choroidal neovascularization 58 LRRK2 mutations 58 mGlu2 3 58 progesterone receptor PR 58 proteomics bioinformatics 58 antiphospholipid antibodies 58 dopamine D2 58 functional gastrointestinal disorders 58 epigenetic therapies 58 lymphoid cells 58 subcortical 58 patient subpopulations 58 CB1 antagonists 58 demyelinating diseases 58 CDKN2A 58 apolipoprotein E APOE 58 HNPCC 58 anterior temporal 58 deCODE AF TM 58 5 HT2C receptor 58 glutamic acid decarboxylase 58 etiologic agent 58 podocyte 58 Neurobiological 58 MTHFR 58 conserved sequences 58 nucleolar 58 subsyndromal 58 paraganglioma 58 silico prediction 58 axonal degeneration 58 T#I [002] 58 chromatin immunoprecipitation ChIP 58 Notch receptors 58 polycythemia vera PV 58 Frontotemporal Dementia 58 mtDNA mutations 58 pDCs 58 STRIDE PD 58 evolvability 58 proteoglycan 58 Multivariate analysis 58 genetic underpinnings 58 TOP2A 58 E#F# 58 CSHL scientists 58 periprocedural MI 58 antiapoptotic 58 monocyte chemoattractant protein 58 allele frequencies 58 gamete formation 58 Epidermal Growth Factor Receptor 58 chromosomal aberrations 58 TRPV1 receptors 58 functional neuroimaging 58 diabetes mellitus DM 58 Heritability 58 allelic 58 protein isoforms 58 STRATEGY FOR AN OPEN 58 beta globin gene 58 Mechanistic 58 cardio metabolic diseases 58 hippocampal atrophy 58 pancreatic endocrine 58 endocannabinoid signaling 58 HepG2 cells 58 BCL#A 58 Lu AA# 58 retinol binding protein 58 therapeutic modality 58 qRT PCR 58 plasma lipid 58 spatial cognition 58 progranulin mutations 58 NPM1 gene 58 CENP E 58 #beta HSD 1 58 morphometrics 58 prognostically 58 chromosomal deletions 58 diffusion tensor 58 epigenetic changes 58 metabolite concentrations 58 proteinases 58 pituitary adenomas 58 neuro developmental disorders 58 lymphoproliferative disorders 58 Genotypic 58 Nedd4 58 biologic plausibility 58 autistic enterocolitis 58 DNA hypermethylation 58 fusion enhancers 58 aneuploidies 58 antisense inhibitors 58 cis regulatory 58 hemoglobinopathies 57 GABA receptor 57 multicellularity 57 biochemical mechanisms 57 subclinical hypothyroidism 57 Li Fraumeni 57 biomarker identification 57 TRIOLEX HE# 57 activated microglia 57 psychiatric disorders ATI 57 IgG1 antibodies 57 neuronal plasticity 57 Akt activation 57 myeloproliferative neoplasms MPNs 57 apolipoprotein E 57 constitutively active 57 thetreatment 57 previously undescribed 57 metacognitive 57 TrkB 57 DLX5 57 PALB2 57 cellular organelles 57 prefrontal regions 57 osteocalcin protein 57 arrhythmogenic 57 autosomal dominant disorder 57 MDR1 57 somatic symptoms 57 endogenous ligand 57 unmeasured confounders 57 thalamic 57 5 HT4 receptor 57 phenotype 57 neuro degenerative diseases 57 indels 57 aberrant activation 57 SHANK3 gene 57 Neuregulin 1 57 histologic findings 57 alpha7 NNR 57 amyloid pathology 57 murine model 57 antiphospholipid syndrome 57 Karlseder 57 histone deacetylase 57 hyperintensities 57 Cardiotoxicity 57 predisposing factors 57 druggable targets 57 medulloblastomas 57 plasma proteome 57 maternally inherited 57 #p# [001] 57 neurogenetic 57 DISC1 57 univariate 57 microarray gene expression 57 PPARg 57 Psychodynamic 57 neuronal function 57 mRNA sequences 57 ENMD # 57 KRAS mutation 57 MYH9 gene 57 mGluR2 57 Asperger syndrome Rett syndrome 57 myeloproliferative neoplasms 57 kidney allograft 57 folate metabolism 57 phylogenetically 57 gene rearrangements 57 R#W [002] 57 MMP# 57 multiple logistic regression 57 inferential statistics 57 #p# [003] 57 demyelinating 57 glycosyltransferase 57 term potentiation LTP 57 mitochondrial gene 57 immunoregulation 57 melatonin receptor 57 FKBP# 57 alpha#beta# integrin 57 hereditary hemochromatosis 57 MAP kinase 57 NR#A# 57 ATTR CM 57 sirtuin activators 57 genomic biomarkers 57 CSF biomarkers 57 intersexuality 57 mitogen activated protein kinase 57 ENPP1 57 schizotypal traits 57 NS4B 57 microstructural 57 familial pancreatic cancer 57 mechanistically 57 JNK1 57 indel 57 ependymomas 57 intestinal microbiota 57 methylenetetrahydrofolate reductase 57 TACI mutations 57 biological pathways 57 compulsive hoarding syndrome 57 microglial 57 chromosome #q# [001] 57 ADAM# 57 validating biomarkers 57 preoperative diagnosis 57 intracellular signaling 57 fronto temporal dementia 57 EF Tu 57 methylation markers 57 FoxO1 57 diathesis 57 ABL1 57 neural progenitor 57 astrocytomas 57 FoxP3 57 #q# deletion syndrome 57 hypothalamus pituitary 57 RhuDex ™ 57 neovascular