Related by context. All words. (Click for frequent words.) 75 hypopneas 72 apnea hypopnea 71 apnea hypopnea index 70 apneic 69 apneas 66 arousals 65 obstructive apnea 65 oxygen desaturation 65 frequent awakenings 65 hypoxemia 64 ventricular tachycardia VT 63 VT VF 63 daytime somnolence 63 hypercapnia 63 akinesia 62 neurologic dysfunction 62 PLMS 62 desaturation 62 hypoventilation 61 Daytime sleepiness 61 asystole 61 Habitual snoring 61 ventricular fibrillation VF 61 atrioventricular block 61 expiratory 61 extrapyramidal symptoms 61 syndrome OSAS 61 hypoperfusion 61 daytime drowsiness 60 sustained ventricular tachycardia 60 cerebral ischemia 60 cerebral perfusion 60 dyspnoea 60 syncope fainting 60 airflow limitation 60 hypovolemia 60 delayed gastric emptying 60 Exclusion criteria 60 hypersomnia 60 prolonged QT interval 60 ictal 60 intermittent hypoxia 60 ventricular tachyarrhythmia 60 coronary stenosis 60 reintubation 60 autonomic dysfunction 60 vasomotor 60 sinus tachycardia 60 atelectasis 60 urethral strictures 60 SRBD 60 unrefreshing sleep 59 untreated obstructive sleep 59 coagulopathy 59 Erythropoietic therapies may 59 ventricular repolarization 59 electroencephalographic 59 severe exacerbations 59 myoclonus 59 ventricular tachyarrhythmias 59 rhinorrhea 59 hyperarousal 59 detrusor 59 bronchial hyperresponsiveness 59 hyperalgesia 59 Tasigna prolongs 59 QTc intervals 59 cortisol secretion 59 Cardiopulmonary bypass 59 exhaled NO 59 cerebral oxygen saturation 59 hemodilution 59 extubation 59 amenorrhea 59 polyuria 59 myocardial fibrosis 59 locomotor activity 59 QT intervals 59 Obstructive sleep apnea OSA 59 urinary albumin 59 serum sodium levels 59 autoregulation 58 tachyarrhythmias 58 pulmonary dysfunction 58 inspiratory 58 SpO 2 58 peak VO2 58 colorectal adenoma 58 Ventricular fibrillation 58 corneal curvature 58 daytime alertness 58 ventricular arrhythmia 58 airflow obstruction 58 myocardial ischemia 58 intima media thickness 58 pulseless electrical activity 58 thromboembolic 58 intracerebral 58 artery occlusion 58 natriuresis 58 PLMs 58 Endothelial function 58 MMSE score 58 activated partial thromboplastin 58 creatine kinase MB 58 hyperoxia 58 Chronic bronchitis 58 psychomotor retardation 58 severe obstructive sleep 58 lung edema 58 glomerular filtration 58 systolic dysfunction 58 β blocker 58 angina chest 58 gross hematuria 58 rCBF 58 wrist actigraphy 58 cerebrovascular events 58 afterload 58 serum estradiol 57 ischaemia 57 blood oxygen saturation 57 IELT 57 torsade de pointes 57 urine albumin 57 hemodynamic instability 57 expiratory flow 57 obstructive sleep 57 tissue oxygenation 57 esophageal acid 57 venous hypertension 57 left ventricular dysfunction 57 haemodynamic 57 creatinine ratio 57 hypoglycemic events 57 vasopressor 57 atrophic gastritis 57 myocardial ischaemia 57 hypercalcaemia 57 #mm Hg 57 UPPP 57 OSAHS 57 impaired cognition 57 postoperative hemorrhage 57 overnight polysomnography 57 QRS duration 57 Myocardial ischemia 57 cytopenias 57 atrial pacing 57 metabolic acidosis 57 levodopa therapy 57 psychomotor agitation 57 thrombus formation 57 atrioventricular valve 57 amenorrhoea 57 mania hypomania 57 nighttime urination 57 nonobstructive CAD 57 cortical activation 57 endometrial thickness 57 Obstructive sleep apnea 57 sleep apneas 57 left ventricular systolic 57 gastro esophageal reflux 57 QTc interval 57 hyperammonemia 57 Heavy menstrual bleeding 57 muscle rigidity 57 nausea photophobia 57 cerebral oxygenation 57 peri procedural 57 oxyhemoglobin 57 multivariate adjustment 57 spirometric 57 inotropic 57 paroxysmal 57 albumin excretion rate 57 sensory disturbances 57 epistaxis 57 anginal pain 57 Sleep disordered breathing 57 salivary flow 57 pulmonary capillary wedge 57 perinatal asphyxia 57 macrovascular events 57 apnea 57 LV dysfunction 57 bleedings 57 hemoptysis 56 cerebrovascular accidents 56 dyspnea 56 normothermic 56 CK MB 56 arterial oxygen saturation 56 clinically meaningful reductions 56 glycosylated hemoglobin HbA1c 56 electrical cardioversion 56 acute decompensation 56 repolarization 56 variant angina 56 artery stenosis 56 decrements 56 chest radiographs 56 unprovoked seizures 56 syncope 56 corticosteroid dose 56 nasal obstruction 56 airway collapses 56 fractional shortening 56 tachypnea 56 serum parathyroid hormone 56 subjective sleepiness 56 parkinsonian 56 opioid analgesia 56 myoclonic 56 Cardiorespiratory fitness 56 affective psychosis 56 polydipsia 56 Postoperative complications 56 hypoglycemic episodes 56 hypoxia induced 56 decompensated heart failure 56 daytime sleepiness 56 apneic episodes 56 lightheadedness dizziness 56 mL kg 56 neurologic deficits 56 irregular menstruation 56 ejection fractions 56 Skin sterol 56 contractile function 56 claudication 56 reinfarction 56 Stress urinary incontinence 56 vasospasm 56 nontraumatic 56 aplindore 56 Index CDAI 56 serum urate 56 aspartate aminotransferase AST 56 habitual snoring 56 postoperative complication 56 mediated dilation 56 nocturnal hypoglycaemia 56 left ventricular diastolic 56 Hypotension 56 ventilatory 56 nasal polyposis 56 recurrent ischemia 56 prolonged immobilization 56 bladder contractions 56 pressure natriuresis 56 coagulation abnormalities 56 polysomnogram 56 intraventricular 56 PLX STROKE targeting 56 abdominal circumference 56 progressive dyspnea 56 hemorrhagic complications 56 β blockers 56 parasomnias 56 carotid stenosis 56 VIIBRYD 56 azoospermia 56 ICD shocks 56 HPA axis suppression 56 carcinoids 56 intracerebral haemorrhage 56 postprocedure 56 adrenocortical 56 Excessive daytime sleepiness 56 vasodilatation 56 dysuria 56 EEG abnormalities 56 alkalosis 55 cerebral infarction 55 fatal myocardial infarction 55 hyperreflexia 55 dopamine antagonists 55 acute ischemia 55 nocturnal hypoglycemia 55 nadolol 55 torsades de pointes 55 aminotransferases 55 detrusor overactivity 55 GI motility 55 polysomnography PSG 55 plasma triglycerides 55 carbohydrate absorption 55 psychophysiological 55 LV ejection fraction 55 vagal 55 blood glucose concentrations 55 bradykinesia 55 estimated glomerular filtration 55 QTcF 55 glycaemia 55 asymptomatic carotid stenosis 55 severe hypoglycemic 55 airway hyperresponsiveness 55 somnolence sleepiness 55 organ perfusion 55 echocardiographic parameters 55 postoperative morbidity 55 postural hypotension 55 apnea OSA 55 theta rhythm 55 cough wheezing 55 rebleeding 55 corrected QT interval 55 bacteriuria 55 esophageal manometry 55 hemodynamic parameters 55 capillary leakage 55 serum phosphate 55 splanchnic 55 syncopal 55 diurnal variation 55 severe hypoglycemia 55 generalized tonic clonic seizures 55 tonsillar hypertrophy 55 intermittent hemodialysis 55 Venous thromboembolism 55 Endothelial dysfunction 55 disordered breathing 55 Holter monitoring 55 thromboses 55 diastolic BP 55 PSVT 55 vasovagal syncope 55 wound dehiscence 55 pathologic fracture 55 nausea emesis 55 deep vein thromboses 55 albumin excretion 55 coronary artery occlusion 55 cough dyspnea 55 pulmonary exacerbations 55 gastric distention 55 plasma homocysteine 55 resuscitated cardiac arrest 55 vomiting constipation 55 atherothrombotic 55 cardioplegic arrest 55 induce orthostatic hypotension 55 excessive daytime sleepiness 55 recurrent seizures 55 vascular dysfunction 55 coronary revascularization 55 #.#mmHg 55 upper airway obstruction 55 nonfasting triglycerides 55 Paroxysmal 55 headache nausea fatigue 55 nighttime awakenings 55 diaphoresis 55 systemic hypotension 55 postoperative AF 55 mL/min/#.# m 2 55 serum PTH 55 tachycardias 55 recurrent miscarriage 55 hypomanic episodes 55 vasoactive 55 dyssynchrony 55 sperm morphology 55 axial length 55 choroidal neovascularization CNV 55 T2 lesions 55 serum aminotransferase levels 55 parenchymal 55 rhythm disturbances 55 flow mediated dilation 55 granulomatous 55 tics involuntary 55 postintervention 55 electrophysiologic 55 nonfatal MI 55 elevated cortisol 55 Brugada syndrome 55 irregular menses 55 FENO 55 depressive symptomatology 55 SGPT 55 etiologic 55 hyperprolactinemia 55 systolic diastolic 55 fluid overload 55 leukocytosis 55 somnolence dizziness 55 hyperresponsiveness 55 paresthesia 55 parkinsonism 55 pulmonary artery pressure 55 serum calcium levels 55 serum bilirubin 54 serum phosphorous 54 menstrual bleeding 54 pupillary 54 anterograde 54 thyroid hormone levels 54 intrathoracic 54 nonfasting triglyceride levels 54 systolic ejection 54 neutropenia thrombocytopenia 54 postoperative bleeding 54 nasal symptom 54 refractory ischemia 54 nocturia 54 serum bicarbonate 54 actigraphy 54 headache nasopharyngitis 54 hepatic enzyme 54 intracerebral hemorrhage 54 intracerebral hemorrhages 54 QRS width 54 cardiac dysfunction 54 crossclamp 54 periprocedural 54 Severe hypoglycemia 54 hyperthermic 54 diastolic pressures 54 blood Phe levels 54 hematuria 54 vessel dilation 54 jugular venous 54 cholinergic tone 54 tremors slowness 54 submaximal 54 oligohydramnios 54 Primary endpoints 54 asymptomatic AF 54 neuronal dysfunction 54 tachyarrhythmia 54 Crohn Disease Activity 54 unexplained fainting 54 neurologic sequelae 54 Chronic pancreatitis 54 muscle twitches 54 hypothalamic pituitary axis 54 carotid IMT 54 baroreflex 54 papilledema 54 postoperative mortality 54 laryngospasm 54 mEq L 54 myocardial contractility 54 inhaled budesonide 54 onset seizures 54 distensibility 54 EXJADE 54 QRS interval 54 tremors rigidity 54 hemoglobin A1c HbA1c 54 acute urinary retention 54 tracheal intubation 54 nasal airflow 54 salmeterol HFA MDI 54 intraobserver 54 nocturnal awakenings 54 thromboembolism 54 Chronic cough 54 receiving XGEVA 54 gastro oesophageal reflux 54 decompensation 54 pressure tachycardia diaphoresis 54 neovascular 54 phonophobia 54 NIHSS score 54 serum urate levels 54 vitamin B# folic acid 54 thoracentesis 54 silent ischemia 54 metabolic alkalosis 54 anterior temporal 54 neurophysiologic 54 #mmHg [002] 54 cerebral angiography 54 thyrotropin levels 54 blood lactate 54 Polysomnographic 54 plasminogen activators 54 airway narrowing 54 comorbid depression 54 neurologic abnormalities 54 caval 54 hypoglycemia unawareness 54 myocardial oxygen 54 AST ALT 54 salivary cortisol 54 Acute pancreatitis 54 supraventricular arrhythmias 54 insomnia somnolence 54 physiologic parameters 54 NIH CPSI 54 bone marrow suppression 54 neutropenic patients 54 pathophysiological mechanisms 54 dysmenorrhoea 54 dizziness constipation 54 systemic corticosteroid 54 hemodynamic variables 54 Subarachnoid hemorrhage 54 serum triglycerides 54 carotid atherosclerosis 54 fatigue shortness 54 Diastolic 54 aminotransferase levels 54 NREM sleep 54 diastolic blood pressures 54 thyroid dysfunction 54 pericardial effusion 54 arterial stiffening 54 cerebral vasospasm 54 hypomanic episode 54 PSA nadir 54 profuse watery diarrhea 54 adenotonsillectomy 54 haematologic 54 irregular menstrual cycles 54 preserved ejection fraction 54 urinary excretion 54 #mmHg [001] 54 circadian misalignment 54 air insufflation 54 polysomnographic 54 HbA 1c levels 54 CP CPPS 54 partial thromboplastin 54 abdominal distention 54 ventricular dilation 54 nasopharyngitis headache 54 endothelium dependent 54 androgen depletion 54 primidone 54 dizziness nausea headaches 54 hepatic steatosis 54 asthma exacerbation 54 Diabetic neuropathy 54 pulmonary resection 54 myocardial reperfusion 54 lobar 54 gastroduodenal 54 pulmonary arterial 54 pulmonary exacerbation 54 aminophylline 54 Cheyne Stokes 54 serum magnesium 54 endocannabinoid signaling 54 esophageal motility 54 leucopenia 54 serum calcium 54 Ejection Fraction 54 diuresis 54 microcirculatory 54 mmHg diastolic 54 impaired glucose metabolism 54 #OHD 54 overt hypothyroidism 54 ventricular remodeling 54 syncopal episode 54 hyperglycaemia 54 osteolytic 54 electroencephalographic EEG 54 loop diuretics 54 aspartate aminotransferase 54 light headedness dizziness 54 cerebral infarctions 54 hypernatremia 54 hypoglycaemic episodes 54 subarachnoid hemorrhages 54 hemodynamics 54 poststroke 54 headaches nausea vomiting 54 parasitaemia 54 heart palpitations dizziness 54 nausea constipation 54 adrenocorticotropic hormone 54 platelet activation 54 dizziness headache nausea 54 cardiovascular hospitalizations 54 Orthostatic hypotension 54 morphometric vertebral fractures 54 postural instability 54 paroxysmal AF 54 serum lipid 54 endobronchial 54 noncardiac 54 HbF 54 vertebrobasilar 53 antidiuretic hormone 53 cerebrovascular accident 53 ecchymosis 53 cardiac autonomic 53 #OHD levels 53 sleep apnea narcolepsy 53 Myocardial infarction 53 CTEPH 53 dysrhythmias 53 somnolence sedation 53 dysfunction LVSD 53 oxygenation 53 coughing shortness 53 pretest probability 53 remnant lipoproteins 53 binary restenosis 53 adenomatous 53 intraocular pressure IOP 53 submaximal exercise 53 oxygen saturations 53 HF hospitalization 53 cervicitis 53 arterial thickening 53 abdominal distension 53 obstructive CAD 53 abnormal uterine bleeding 53 packet jitter 53 Adverse effects 53 rhinoconjunctivitis 53 Infusion Reactions Severe 53 pathologic fractures 53 TEAEs 53 epigastric pain 53 neuromuscular blockade 53 Chronic insomnia 53 coronary perfusion 53 circadian rhythm sleep 53 Wernicke Korsakoff syndrome 53 de novo lipogenesis 53 aortic crossclamp 53 symptomatic VTE 53 unstable angina pectoris 53 Deep venous thrombosis 53 status epilepticus 53 serum uric acid 53 left ventricular LV 53 timepoints 53 coronary revascularization procedures 53 serum cortisol 53 neurodevelopmental impairment 53 disorientation convulsions 53 constipation predominant IBS 53 subthreshold 53 vein thrombosis 53 serum sodium 53 sinus bradycardia 53 CHD CVD 53 cardiac contractility 53 dizziness blurred vision 53 Somnolence 53 VATS lobectomy 53 COPD exacerbations 53 pulmonary vascular 53 headache abdominal pain 53 myocardial infarction stroke 53 C1 INH deficiency 53 6MWD 53 radiochemotherapy 53 Sleep disturbances 53 eNO 53 cTnT 53 fetal malformations 53 dizziness lightheadedness 53 interstitial fluid 53 sodium excretion 53 generalized dystonia 53 intima media thickness IMT 53 inotropes 53 cardiac tamponade 53 ml kg 53 plasma pharmacokinetics 53 mL/min/#.# m2 53 polysomnography 53 symptom exacerbation 53 leiomyomas 53 post thrombotic syndrome 53 hyperphenylalaninemia HPA due 53 fraction LVEF 53 saline infusion 53 EEG electroencephalogram 53 elevated IOP 53 cortical excitability 53 denervation 53 bronchopulmonary dysplasia 53 intravaginal ejaculatory latency 53 CDAI score 53 diaphragmatic 53 nonfatal myocardial infarction 53 mIU L 53 electrolyte abnormalities 53 fructosamine 53 amyloid deposition 53 symptom flare ups 53 calculated creatinine clearance 53 neonatal morbidity 53 VAD implantation 53 Non inferiority 53 ischemia induced 53 aminotransferase ALT 53 irritability depression 53 palpitations dizziness 53 secondary efficacy endpoint 53 hyperpyrexia 53 neurologic complications 53 recurrent venous thromboembolism 53 cardioembolic stroke 53 RLS symptoms 53 hypotensive 53 anal incontinence 53 erythrocyte sedimentation rate 53 Quiescent current 53 Critical limb ischemia 53 ACh 53 oral hypoglycemic agents 53 Cardiac arrhythmia 53 gastrointestinal disturbances 53 glycated hemoglobin levels 53 allostatic 53 PCWP 53 platelet dysfunction 53 stenotic 53 KCNH2 53 inhaled corticosteroid therapy 53 electrocardiographic 53 Peripheral arterial disease 53 nausea somnolence 53 transthoracic 53 bullous 53 intracranial hemorrhage ICH 53 OGTT 53 elevated serum creatinine 53 discomfort bloating 53 femoral neck fracture 53 PSADT 53 blood oxygenation 53 metabolite concentrations 53 radicular pain 53 urinary N telopeptide 53 hyperacute 53 urinary calcium excretion 53 acetabular fracture 53 nonvascular 53 cardiac ischemia 53 pathophysiologic 53 subsyndromal 53 differential gene expression 53 plasma creatinine 53 variceal bleeding 53 diarrhea dyspepsia 53 intravitreal injections 53 sequela 53 pulmonary artery hypertension 53 ipsilateral stroke 53 liver steatosis 53 oxygen saturation 53 ropivacaine 53 pulseless ventricular tachycardia 53 elevated LDH 53 anovulation 53 chronic renal insufficiency 53 fatigue nausea vomiting 53 valvular heart disease 53 HPA axis 53 fever chills nausea 53 tremors stiffness slowness 53 androgen excess 53 Heritability 53 electroencephalograms 53 ileus 53 intravascular volume 53 dizziness nausea diarrhea 53 macrovascular 53 perioperative complications 53 Ischemic 53 aneurysmal subarachnoid hemorrhage 53 expiratory pressure 53 postprandial glucose 53 lactate dehydrogenase LDH 53 primary aldosteronism 53 nonarteritic anterior ischemic optic 53 Scale EDSS score 53 fasting glucose levels 53 proton MR spectroscopy 53 methacholine challenge 53 #q# deletion syndrome 53 upper gastrointestinal bleeding 53 PaO 2 53 dyskinesias 53 incontinence episodes 53 distension 53 serum sodium concentration 53 neurodevelopmental outcome 53 extraocular 53 colorectal adenomas 53 arrhythmogenic 53 urinary albumin excretion 53 cholestasis 53 Acute respiratory distress 53 mild renal insufficiency 53 CPAP adherence 53 mitral stenosis 53 chronic venous insufficiency 53 perioperative morbidity 53 hepatic glucose production 53 recurrent ischemic 53 pleurodesis 53 eosinophilia 53 dopaminergic therapy 53 coronary artery dissection 53 Nocturia 53 LVSD 53 cardiopulmonary bypass CPB 53 myocardial function 53 serum HCV RNA 53 Epworth Sleepiness Scale 53 arterial thromboembolic events 53 mucus glands 53 ventricular dyssynchrony 53 elevated TSH 53 overactivity 53 hematopoietic cancers 53 adrenal insufficiency 53 hepatic enzymes 53 thrombophlebitis 53 prefrontal cortical 53 neurologic symptoms 53 gastroesophageal 53 hyperuricaemia 52 choroidal 52 premorbid 52 motor neuropathy 52 edema swelling 52 lumbar disk herniation 52 gastric pH 52 d dimer 52 intestinal motility 52 transaminases 52 nausea dizziness vomiting 52 subtrochanteric 52 creatine kinase 52 cardiac perfusion 52 systolic BP 52 chronic thromboembolic pulmonary 52 perioperative mortality 52 neurologic impairment 52 malperfusion 52 plasma lipids 52 neurocognitive functioning 52 lung epithelium 52 HOMA IR 52 Thrombotic thromboembolic complications 52 ml min 52 respirations 52 recurrent VTE 52 pulse amplitude 52 intraoperative complications 52 autoantibody levels 52 posttreatment 52 constipation nausea 52 chills headache 52 atherogenic dyslipidemia 52 somnolence headache 52 rebreathing 52 vitreous floaters 52 symptom severity 52 afib 52 ischemic optic neuropathy 52 involuntary muscle contractions 52 #.#ng/ml 52 superior mesenteric artery 52 headaches dizziness disorientation nausea 52 nonhematologic adverse reactions 52 infarct size 52 microsleep 52 creatinine clearance 52 beta blocker therapy 52 tranylcypromine 52 symptomatic intracranial 52 pyelonephritis 52 nasal itching 52 Mechanical ventilation 52 hyperglycaemic 52 dyspnea shortness 52 prefrontal regions 52 hyperactivity impulsivity 52 subclinical hypothyroidism 52 Glomerular filtration rate 52 arterial hypotension 52 pCR 52 wheezing shortness 52 Preterm infants 52 fasting triglycerides 52 PAOD 52 Untreated sleep apnea 52 echocardiographic 52 #mg/dL [001] 52 dyspareunia 52 convulsive seizures 52 arteriolar 52 neurohormones 52 EDSS scores 52 gastric acid secretion 52 nasal stuffiness 52 elevated creatinine 52 thrombocytopenic 52 HbA 1C 52 leukocyte counts 52 QTc prolongation 52 angiographically 52 total cholesterol triglycerides 52 Strenuous exercise 52 hyperintense lesions 52 cryptogenic stroke 52 baseline HbA1c 52 EDSS score 52 arterial calcification 52 dizziness somnolence 52 ischemic cardiomyopathy 52 electromyographic EMG 52 monoamine 52 cystoscopic 52 dizziness fatigue 52 catecholamine 52 intact parathyroid hormone 52 paralytic ileus 52 HAM D# 52 coronary catheterization 52 tremor rigidity 52 ANCA associated 52 photic 52 glycated hemoglobin HbA1c 52 proximal DVT 52 elevated ALT 52 serum creatinine levels 52 tardive dyskinesia TD 52 manometry 52 hypophosphatemia 52 NYHA functional class 52 lethal arrhythmias 52 Symptom severity 52 hypercoagulable 52 intracellular pH 52 hypogonadotropic hypogonadism 52 urine leakage 52 tissue oxygen saturation 52 microvascular disease 52 chronicity 52 Eisenmenger syndrome 52 Hemorrhagic stroke 52 â ‰ ¥ 52 corneal thickness 52 shorter telomere length 52 parkinsonian symptoms 52 bothersome symptom 52 Hemodynamic 52 BPPV 52 subcutaneous infusion 52 sensory gating 52 Inventory BPI 52 Ventricular Tachycardia 52 brain parenchyma 52 acromegalic patients 52 generalized seizures 52 cerebrovascular 52 renal tubular 52 habitual snorers 52 Genetic predisposition 52 hyperhydrosis 52 brachial artery flow 52 anemia neutropenia 52 spontaneous bacterial peritonitis 52 affective psychoses 52 protein excretion 52 glomerular filtration rate 52 serum clusterin levels 52 spontaneous bowel movements 52 resynchronization therapy 52 Y BOCS 52 CI -#.# 52 aortic stiffness 52 Ischemia 52 HER2 expression 52 neurologic outcomes 52 thrombocytosis 52 Breathlessness 52 urothelial 52 Abdominal pain 52 Fasting plasma glucose 52 hypoxic ischemic encephalopathy 52 rate variability HRV 52 abnormally elevated 52 overt nephropathy 52 polymorphic ventricular tachycardia 52 angiographic restenosis 52 homocysteine concentrations 52 nerve conduction velocity 52 thiazide diuretic 52 hyperexcitability 52 EtCO2