Related by context. All words. (Click for frequent words.) 69 immunomodulatory effects 69 p# activation 68 cytoprotective 68 antitumor efficacy 68 intracellular uptake 67 CB2 receptor 67 mediated inhibition 67 antitumoral 66 intestinal microflora 66 vivo potency 66 selective inhibition 66 spermidine 66 #ME# 66 ERK1 2 66 Th2 cytokines 66 immune modulating 66 inhibitory effects 66 antiapoptotic 66 immunological responses 65 IL 1ß 65 cytotoxic effects 65 pleiotropic effects 65 antidepressant efficacy 65 effector function 65 immuno modulatory 65 p# MAPK 65 pathophysiological effects 65 dopamine reuptake 65 immunotoxins 65 HIF 1alpha 65 chemopreventive 65 antiangiogenic 65 glucagon receptor 65 glucose homeostasis 65 erythropoietic 65 fibrotic disease 65 potent inhibitors 65 mTOR inhibitors 65 mTOR inhibition 65 Valortim ® 65 nephrotoxicity 65 bioactivity 65 TNF α 64 prostaglandin synthesis 64 lipid lowering therapies 64 IFN g 64 immunomodulation 64 IFN γ 64 neuroinflammation 64 microglial activation 64 gamma tocotrienol 64 cyclic adenosine monophosphate cAMP 64 chemosensitivity 64 selective modulator 64 PTP 1B 64 pharmacokinetic interactions 64 norepinephrine reuptake inhibition 64 antiangiogenic agents 64 calcitonin gene related 64 γ secretase 64 pharmacodynamic markers 64 p# alpha [001] 64 interferon γ 64 plasma pharmacokinetics 64 SIRT1 activators 64 proteoglycan 64 antitumor effect 64 pertussis toxin 64 Neuroprotective 64 XL# inhibits 64 Tß4 64 platelet activation 64 prostanoid 64 cardioprotective effects 63 antiinflammatory 63 HCV replication 63 DNA methyltransferases 63 antitumor 63 inhibitory effect 63 neurotrophic 63 acetylcholinesterase AChE 63 TNFalpha 63 FasL 63 ERK signaling 63 Vidofludimus 63 preclinically 63 HepG2 cells 63 JAK inhibitors 63 VEGF inhibitors 63 miR #a [001] 63 receptor inhibitor 63 pharmacodynamic parameters 63 antioxidant supplementation 63 p# inhibitor 63 neuroprotective properties 63 superoxide dismutase 63 EBV infection 63 steroidogenic 63 immune modulatory 63 chlamydial 63 Kinoid 63 anticancer activity 63 Fc receptor 63 MAPK pathway 63 immunomodulatory properties 63 potentiating 63 CETP inhibition 63 Treg cell 63 serotonergic 63 humanized monoclonal 63 mGluR2 NAM 63 growth hormone secretion 63 Clusterin 63 NF KB 63 CRAC channel 63 analgesic effects 63 PC# cells 63 IFN gamma 63 hypericin 63 proinflammatory cytokine 63 drug metabolizing enzymes 63 autoantibody levels 63 pro angiogenic 63 oestrogenic 63 osteoclast formation 63 A3 adenosine receptor 63 anti amnesic 63 cAMP signaling 63 physiologic mechanisms 63 plasma lipid 63 potent antibacterial 63 homodimers 63 NFkappaB 63 HCV protease inhibitors 63 innate immune responses 63 cMET 63 neuro protective 63 Abeta# 63 RNAi mediated 63 noradrenergic 63 AT1R 62 muscarinic 62 Fibroblast Growth Factor Receptor 62 PI3K/mTOR 62 coexpression 62 hydrolases 62 CCR3 62 TGR5 62 mimetics 62 thromboxane A2 62 pharmacologic approaches 62 menadione 62 oral prodrug 62 immunopathology 62 mecamylamine 62 RAS RAF MEK 62 CEACAM1 62 RANK Ligand 62 Interferon alpha 62 K ras mutations 62 NPD1 62 beta adrenergic 62 androgen receptor AR 62 immune modulator 62 VEGF receptor 62 anti angiogenic drugs 62 pharmacodynamic PD 62 ADME properties 62 nitrotyrosine 62 synthase TS 62 hepatic fibrosis 62 transgene expression 62 CYT# potent vascular disrupting 62 tryptase 62 siRNA mediated 62 non nucleoside 62 eicosanoid 62 NMDA antagonists 62 HDAC6 62 mevalonate 62 GPx 62 PPARg 62 LRP5 62 receptor subtypes 62 antiproliferative effects 62 adrenocorticotropic hormone ACTH 62 HuLuc# 62 vasodilatation 62 galectins 62 biologic therapeutics 62 proteolytic degradation 62 vWF 62 systemic toxicity 62 cultured hippocampal neurons 62 neurite outgrowth 62 renal fibrosis 62 motor neuron degeneration 62 4E BP1 62 monomeric 62 NMDA antagonist 62 nutlin 62 flavopiridol 62 serum PTH 62 Granulocyte Colony Stimulating Factor 62 CYP #A# 62 HIF PH inhibitors 62 intestinal mucosal 62 vidofludimus 62 protein biosynthesis 62 gamma secretase inhibitor 62 apolipoprotein B 62 NTDDS 62 GMX# 62 cytostatic 62 HIF 1a 62 #beta HSD1 62 amyloidogenic 62 oxidases 62 amyloid peptide 62 siRNA therapeutics 62 Preclinical studies suggest 62 Symadex 62 TRAIL induced apoptosis 62 glycolytic 62 ACh 62 azole 62 Human cl 62 peripherally acting 62 resolvins 62 chemoprotective 62 biologic pathways 62 PHD2 62 NS#/#A protease 62 redox active 62 serum biomarkers 62 targeting PCSK9 62 protein tyrosine phosphatase 1B 62 anti leukemic 62 ERK phosphorylation 62 c MYC 62 NKG2D 62 BChE 62 myeloproliferative diseases 62 sGC 62 ERK pathway 62 IgG1 antibodies 62 beta defensins 62 endothelial activation 62 differential gene expression 62 COX enzymes 62 IKK2 62 pro apoptotic 61 serine threonine 61 secretory pathway 61 histone deacetylase HDAC 61 N methyl 61 underlying molecular mechanisms 61 immunomodulatory 61 phosphate S1P 61 ADAMTS# 61 overactivation 61 virulence genes 61 antibody mediated 61 acetylcholinesterase 61 humoral responses 61 IL #p# 61 humoral immunity 61 endogenous ligands 61 #HT#A receptor 61 demethylation 61 plasma renin activity 61 Elevated serum 61 thymidylate synthase TS 61 Aβ 61 immunoregulatory 61 acetylcholine receptor 61 N Acetyl 61 chemopreventive agent 61 pleiotropic 61 cholesterol homeostasis 61 IMPDH 61 melatonin receptor 61 HIF 1α 61 Akt activation 61 carbamate insecticides 61 Tasimelteon 61 isoenzymes 61 Interferon Beta 61 Angiotensin converting enzyme 61 cardiac repolarization 61 interleukin IL 61 N acetyl 61 antiandrogens 61 antiviral efficacy 61 FGFs 61 immune stimulatory 61 MEK ERK 61 physico chemical properties 61 rolipram 61 heparanase 61 atherogenesis 61 inhibiting enzymes 61 myeloperoxidase 61 adipocyte differentiation 61 serpin 61 partial agonists 61 PTHrP 61 PPARγ 61 NS5A 61 neuronal dysfunction 61 STAT3 signaling 61 nAChRs 61 biochemical abnormalities 61 splice variants 61 ENaC 61 Thiovir 61 drug metabolizing enzyme 61 JAK#/JAK# 61 BACE1 61 dose dependently 61 endoxifen 61 suppressor cells 61 riociguat 61 Posiphen 61 tumorigenicity 61 act synergistically 61 receptor blocker 61 neuronal signaling 61 alfentanil 61 CYP#B# 61 interleukins 61 hepatotoxic 61 allergic inflammation 61 humanized monoclonal antibodies 61 NLRP3 61 enzymatic pathways 61 synovial cells 61 mitogenic 61 immunotoxin 61 glutamyl 61 isoenzyme 61 mTOR mammalian target 61 Epothilones 61 subcellular compartments 61 TGF beta signaling 61 SSc 61 neuroinflammatory 61 adrenal hormone 61 estrogen receptor beta 61 LNP formulations 61 HDAC inhibition 61 potent inhibition 61 DNA demethylation 61 peptide inhibitors 61 membrane permeability 61 galectin 61 thrombin receptor 61 Onconase 61 ApoA l 61 carcinoembryonic antigen 61 flavanones 61 p# Shc 61 serum concentrations 61 Hh pathway 61 oxysterols 61 factor HGF 61 immunostimulatory 61 Th1 type 61 AChE 61 CYP #D# 61 Lyn kinase 61 antiplatelet therapies 61 tyrosine phosphorylation 61 bacterial virulence 61 mGluR5 antagonist 61 selectively inhibited 61 TTR gene 61 PECAM 1 61 peroxisomal 61 developmental neurotoxicity 61 histone deacetylases 61 sulindac 61 PTPN# 61 tetrahydrobiopterin 61 antitumor immunity 61 Poly ICLC 61 effector functions 61 recombinant erythropoietin 61 c myc gene 61 inflammatory cytokine 61 DNMT1 61 targeting CD# 60 insulin sensitizing 60 aberrantly activated 60 selective agonists 60 SERMs 60 CCR1 60 potentiation 60 enzyme inhibitors 60 secretase 60 microtubule targeting 60 TGF ß 60 immunomodulating 60 Flt3 60 chromosomal rearrangement 60 interferon IFN 60 neuroregenerative 60 FGFR1 60 enzyme inhibitor 60 OGG1 60 LPS induced 60 radiosensitivity 60 excitotoxic 60 butyrylcholinesterase 60 Antitumor 60 PDE1 60 hedgehog pathway 60 protein tyrosine phosphatase 60 IgG4 60 downregulating 60 cathepsins 60 collagen degradation 60 HIF PH 60 bronchial epithelial cells 60 LHRH antagonists 60 favorable pharmacokinetic 60 cardiotoxic 60 antiproliferative 60 Amino acid 60 gastric mucosa 60 Corgentin 60 p#Kip# 60 elastase 60 colorectal carcinogenesis 60 CD# upregulation 60 neurotrophic factors 60 oral JAK1 60 anti miRs 60 HSP# inhibitors 60 pan HDAC inhibitor 60 C. difficile toxins 60 osteoclast activity 60 DXL# 60 viral kinetics 60 gastrointestinal motility 60 mitogen activated protein kinase 60 anti atherogenic 60 BRAF inhibitors 60 ß amyloid 60 serum antibodies 60 activate p# 60 C5aR 60 druggable target 60 suppress viral replication 60 Upregulation 60 quinolone 60 receptor agonists 60 airway hyper responsiveness 60 antitumour 60 PDGFR 60 lymphocyte activation 60 interleukin IL -# 60 systemically administered 60 potent cytotoxic 60 serotonin synthesis 60 serine proteases 60 selective antagonist 60 anti CD3 antibody 60 LDL receptor 60 Valproic acid 60 immuno inflammatory 60 antitumor effects 60 tumor suppressor proteins 60 antiarrhythmic 60 Hematologic toxicity 60 antimetabolites 60 TNFa 60 erythropoiesis 60 R baclofen 60 c MET 60 caspofungin 60 glucan 60 PDGF receptor 60 RNAi pathway 60 alkylating agent 60 PEDF 60 multidrug resistance 60 TGF ß1 60 platelet adhesion 60 hematological parameters 60 enzymatic pathway 60 Cytotoxic 60 transgenic rats 60 agonists antagonists 60 #beta HSD 1 60 cotransporter 60 anticholinergic agents 60 5 HT4 receptor 60 chemopreventive agents 60 IGFBP 3 60 TGF beta1 60 immunotoxicity 60 inhibiting mTOR 60 HMG CoA reductase inhibitors 60 SIRT2 60 maturation inhibitors 60 beta lactamases 60 probiotic supplementation 60 IL #E 60 neuronal plasticity 60 adrenoceptor 60 hypoxia inducible factor 60 β catenin 60 LTB4 60 potent antiproliferative 60 GABAA receptors 60 inhibitory neurotransmitters 60 ligand induced 60 E selectin 60 serum lipid 60 peroxidation 60 microglial 60 glucocorticoid receptor 60 S/GSK# 60 neuropsychiatric diseases 60 cathepsin B 60 Squalamine 60 Alpha lipoic acid 60 inhibiting tumor 60 histone acetyltransferase 60 fosbretabulin 60 deacetylation 60 arginase 60 NADPH oxidase 60 lenalidomide dexamethasone 60 cytotoxic T lymphocyte 60 anti resorptive 60 perilipin 60 M1 muscarinic 60 lysosomal enzyme 60 antineoplastic 60 IL 1β 60 treating neuropathic pain 60 ABL1 60 benfotiamine 60 PPAR gamma agonists 60 myopathy rhabdomyolysis 60 cardiometabolic disorders 60 sirtuin enzymes 60 lymphotoxin 60 interleukin IL -6 60 novel peptide 60 TGF b 60 pharmacokinetic equivalence 60 serine protease 60 neuroprotection 60 PDE4 inhibitors 60 LNCaP cells 60 proteinase 60 heme oxygenase 1 60 lactate dehydrogenase 60 alpha#beta# integrin 60 peptidic 60 striatal dopamine 60 CG# [003] 60 CB1 antagonists 60 Gleevec resistant 60 Aspergillus species 60 fatty acid metabolism 60 Enkephalin 60 GSOs 60 nanomolar 60 Cdc7 60 histone acetylation 60 adrenal suppression 60 BAL# [002] 60 tumor necrosis 60 serotonin reuptake 60 CYP3A 60 macrolide antibiotics 60 PKC inhibitors 60 idarubicin 60 p#NTR 60 DHFR 60 epigenetic therapies 60 VDAs 60 soluble CD# 60 PBMCs 59 urinary excretion 59 lysosomal 59 peptide CGRP 59 primary hyperparathyroidism 59 imatinib resistance 59 LDL oxidation 59 Notch receptors 59 acid GABA 59 protein kinase C 59 proteolytic 59 Akt signaling 59 ENMD # 59 Th2 responses 59 chemoresistance 59 MetAP2 59 5 HT2A receptor 59 estrone 59 TLR antagonists 59 enkephalin 59 metabolic alterations 59 thyrotropin 59 cellular prion protein 59 indinavir 59 COX2 59 BCL2 59 PRT# 59 bile acid 59 Anticalins R 59 CBLC# 59 radezolid 59 Neuropeptide Y 59 mPGES 1 59 CGRP 59 receptor antagonism 59 allopregnanolone 59 proton pump 59 GABAB receptors 59 nicotinamide 59 renal toxicity 59 hypoxic tumors 59 tumor vasculature 59 IFN beta 59 FBPase 59 HGS ETR2 59 delafloxacin 59 bezafibrate 59 E. faecalis 59 mitochondrial enzyme 59 #ß 59 binding affinities 59 fluconazole resistant 59 autophagic 59 Fc fusion protein 59 sequence homology 59 systemic bioavailability 59 RAF kinase 59 Pseudomonas aeruginosa infections 59 hippocampal neurons 59 plasma kallikrein 59 proto oncogene 59 Fas ligand 59 mechanistic insights 59 chitinase 59 dopamine D2 59 eNOS 59 cytolytic 59 bactericidal activity 59 etiologic 59 Y2 receptor 59 mucosal immunity 59 Dietary restriction 59 posttranslational modifications 59 ON #.Na 59 TNF receptors 59 pharmacodynamic properties 59 HER2 expression 59 PDE4 59 underlying pathophysiology 59 hypothalamic pituitary 59 uric acid lowering 59 phosphatases 59 TPMT 59 cannabinor 59 Xanafide 59 osteoblast 59 glucosides 59 pyrimidine 59 Pgp 59 L Ergothioneine 59 endocannabinoid signaling 59 cytochromes P# 59 miRs 59 modulatory 59 antifibrotic 59 fusion enhancers 59 anti inflammatory cytokine 59 tau phosphorylation 59 EphA2 59 anti apoptotic 59 axonal damage 59 receptor partial agonist 59 PPARgamma 59 Solorel TM 59 matrix metalloproteinases 59 vascular disrupting agents 59 pharmacological chaperone 59 NFκB 59 FGFR4 59 polyamine 59 cytokine receptor 59 periodontal tissues 59 replicon 59 atacicept 59 antioxidative 59 amyloid β 59 intestinal epithelium 59 galantamine 59 GLYX 59 neurotrophic factor 59 muscarinic receptors 59 adenylate cyclase 59 Smac mimetics 59 glucocorticoid receptors 59 extracellular dopamine 59 prodrugs 59 Dehydrogenase 59 autoimmune reactions 59 mitochondrial toxicity 59 activated microglia 59 CaPre TM 59 lipoic acid 59 antitumor activity 59 bronchodilatory 59 anti CD3 59 Superoxide 59 telomerase activation 59 inverse agonist 59 upregulating 59 glycolipids 59 retinoid X 59 NR2B subunit 59 cytochrome P# #A# 59 antiresorptive 59 ginsenosides 59 PEGPH# 59 mutant huntingtin 59 mineralocorticoid 59 trophoblast cells 59 SCD1 59 resistant mutants 59 metabolizing enzymes 59 neurosteroid 59 myocardial function 59 dosing frequency 59 mGluR2 59 novel VDA molecule 59 TRX1 59 antigenicity 59 ABCB1 59 clusterin 59 glycosylated 59 CCR2 59 HbF 59 pressure natriuresis 59 nucleosides 59 phosphodiesterase inhibitors 59 monoamines 59 interferon beta 59 receptor activation 59 substrates inhibitors 59 immunologic responses 59 tumor suppressor PTEN 59 NO synthase 59 bradykinin 59 Aldosterone 59 hyperphenylalaninemia HPA due 59 Valortim R 59 partial agonist 59 potency selectivity 59 pharmacological inhibition 59 TMEM#B 59 activin 59 neuron degeneration 59 deacetylase inhibitors 59 hyperprolactinemia 59 activated lymphocytes 59 topoisomerase 59 mucociliary clearance 59 induces antibodies 59 NS4A 59 vasoactive 59 inhibit enzymes 59 uricase 59 UsiRNAs 59 PDGF alpha receptor 59 HDAC enzyme 59 MAPK signaling pathway 59 S6K 59 hippocampal synapses 59 Angiotensin II 59 tricyclic 59 somatostatin 59 cis retinoic acid 59 microsomal 59 HSP# inhibitor 59 CD# monoclonal antibody 59 cholesterol efflux 59 small molecule activators 59 fatty acid biosynthesis 59 p# MAP kinase 59 mutant huntingtin protein 59 dihydrofolate reductase 59 Soy isoflavones 59 dasatinib Sprycel 59 SIRT1 activation 59 pharmacologic 59 nicotinic acetylcholine receptor 59 murine model 59 velafermin 59 cyclin E 59 myofibroblast 59 receptor antagonists 59 CCL5 59 XmAb# 59 pathogenic mechanisms 59 uroguanylin 59 ultrastructural 59 CCR9 antagonist 59 V#F mutation 59 SPIRIVA ® 59 hyperalgesia 59 Bioavailability 59 AAG geldanamycin analog 59 kidney urologic 59 Vitamin D2 59 uPAR 59 KL4 surfactant 59 mutated K ras 59 tolerability pharmacokinetics 59 vimentin 59 NMDAR 59 phospholipase 59 prostaglandin E1 59 oxidative metabolism 59 tumor suppressor protein 59 haematopoietic 59 apoptotic pathway 59 fulvestrant 59 serum BDNF 59 Th1 cells 59 PXD# 59 leukotriene B4 59 Janus kinase 59 HDAC2 59 frataxin 59 antidiabetic 59 peptide antigens 59 leukocyte adhesion 59 Raf kinase 59 MTP inhibitor 59 prostate carcinogenesis 59 anti Xa 59 isoform selective 59 secretory phospholipase A2 sPLA2 59 biotransformation 59 Dasatinib 59 AMPK activators 59 potent anticancer 59 IL 1beta 59 recombinant interferon 59 neuronal nicotinic receptors NNRs 59 ligand TRAIL 59 NF kappaB activation 59 oligomeric 59 parasitemia 59 RNAi therapeutic targeting PCSK9 59 granzyme 59 hypoperfusion 59 synthetic lethality 59 alpha#beta# 59 N acetyl cysteine 59 pharmacologic intervention 59 JAK2 enzyme 59 nicotinic acetylcholine receptors 58 anaphase promoting complex 58 histone deacetylase inhibitor 58 peroxisome proliferator activated 58 cytochrome P# 58 PIGF 58 prostaglandin E2 PGE2 58 protein tyrosine phosphatases 58 reverse transcriptase inhibitors 58 CTAP# Capsules 58 small molecule defensin 58 diphosphate 58 pRb 58 molecular determinants 58 proteolytic enzymes 58 alkylating 58 paricalcitol 58 cytotoxic agents 58 colonic mucosa 58 CCX# 58 anti neoplastic 58 alpha synuclein protein 58 RANK ligand 58 kinase inhibition 58 methyltransferases 58 fermentative 58 eIF4E 58 MAP kinase 58 MMP9 58 antimetastatic 58 mGlu2 3 58 Cytochrome P# 58 prostacyclins 58 peroxynitrite 58 TLR agonists 58 Reverse Cholesterol Transport 58 receptor mediated 58 Anticalins ® 58 oral mTOR inhibitor 58 Aurora Kinase 58 glutamate receptors 58 P selectin 58 Cyclin E 58 IFNs 58 tumorigenic 58 PKC isoforms 58 endothelial nitric oxide 58 parthenolide 58 N. gonorrhoeae 58 cyclic AMP cAMP 58 phenelzine 58 analgesic efficacy 58 Dysregulation 58 racemate 58 inhibiting COX 58 direct thrombin inhibitors 58 cytotoxicity 58 enzyme cofactor 58 AKT1 58 ERK activation 58 Prolactin 58 phagocyte 58 toxic beta amyloid 58 peptide fragments 58 fibrate drugs 58 Factor Receptor 58 synaptogenesis 58 NKT cell 58 TNFα 58 beta lactam antibiotic 58 peroxidase 58 Pharmacological 58 IgG1 58 echinocandins 58 phosphorylated tau 58 substrate specificity 58 SOCS3 58 CD# expression [001] 58 FKBP# 58 bleomycin 58 tenascin C 58 tumor hypoxia 58 #HT#A 58 collagen synthesis 58 thiopurine 58 beta. 58 outer membrane proteins 58 natriuretic 58 inducible nitric oxide synthase 58 58 enzymatic activity 58 anti dyslipidemic 58 alpha adrenergic 58 Inhibitory 58 FLT3 58 endothelin receptor 58 Inflammatory diseases 58 molecular biomarkers 58 potent neuroprotective 58 hematopoietic cells 58 enzyme phosphodiesterase 58 IFN ß 58 pharmacological 58 indibulin 58 CP CPPS 58 ACEIs 58 intact parathyroid hormone 58 cyclooxygenase 2 58 apoptosis inducing 58 Anavex #-# 58 β amyloid 58 mTOR kinase 58 PP2A 58 osteogenic 58 molecularly targeted 58 GSK3B 58 quinone 58 cytokines IL 58 granzyme B 58 gene rearrangements 58 neutralizing antibody 58 curcuminoids 58 prostaglandin E 58 glutathione GSH 58 inosine 58 HDAC 58 upregulates 58 5 HT2A serotonin