Related by context. Frequent words. (Click for all words.) 82 multiple ascending dose 74 dose escalation trial 72 dose escalation study 69 Phase 1b 69 placebo controlled 68 Phase 2a clinical 68 Phase 2b study 68 Phase Ib 68 Phase 2a trial 67 randomized placebo controlled 67 safety tolerability 66 Phase 2b trial 66 Phase III clinical 66 Phase IIa clinical 66 Phase IIa 65 Phase IIa trial 65 blind randomized placebo 65 double blind placebo 65 Phase IIb 64 pivotal Phase III 64 Phase IIb clinical 64 pharmacokinetic 64 phase IIb 64 randomized double 64 pharmacokinetics 64 Phase 2a 64 multicenter randomized double 63 Phase IIb trial 63 pharmacodynamics 63 blind placebo controlled 62 pharmacokinetic profile 62 blind randomized 62 Phase 2b clinical 62 randomized controlled 60 tolerability 60 dose escalation 60 label dose escalation 60 Phase III pivotal 60 Phase 2b 60 Phase III 60 tolerated dose MTD 59 clinical trial 59 randomized clinical 59 IDX# 59 randomized #:# 58 randomized 58 randomized Phase 58 Phase III clinical trials 58 Phase II 57 randomized controlled clinical 57 multicenter 57 pharmacodynamic 57 RG# [001] 56 mg BID 56 RDEA# 56 pivotal Phase 56 mg dose 56 investigational compound 56 HGS ETR1 56 HCV infected 56 CK # 56 IND enabling 55 dose limiting toxicities 55 investigational oral 55 orally administered 55 ofatumumab 55 prospective cohort 55 initiate Phase 55 antiviral activity 55 prospective randomized 55 relapsing remitting multiple sclerosis 55 investigational drug 54 PRX # 54 Clinical Study 54 randomized controlled trial 54 oral formulation 54 PF # [001] 54 Phase III trials 54 HCV genotype 1 54 immunogenicity 54 NGX# 54 Phase 54 laquinimod 54 confirmatory Phase 3 54 LEVADEX 53 IMGN# 53 CRx 53 humanized monoclonal antibody 53 evaluable patients 53 preclinical studies 53 DSMB 53 JANUVIA 53 multicenter study 53 ZYBRESTAT 53 tolerability profile 53 unblinded 53 Initiates Phase 53 Zerenex 52 evaluable 52 IPX# 52 MLN#