Related by context. All words. (Click for frequent words.) 68 A3 adenosine receptor 67 antitumoral 66 cytoprotective 66 splice variants 65 peptide antigens 65 PI3K/mTOR 65 heparanase 65 immune modulating 65 effector function 64 cytostatic 64 Preclinical studies suggest 64 ERK signaling 64 miR #a [002] 64 DNA methyltransferases 64 favorable pharmacokinetic profile 64 murine models 64 ENMD # 64 ligand binding 64 histone deacetylase inhibitor 64 potent inhibitors 64 antiproliferative effects 64 potent cytotoxic 64 anti CD3 64 enzyme inhibitor 64 Protein Kinase C 64 ADME properties 63 granzyme B 63 antimitotic 63 immunoregulatory 63 potently inhibited 63 sd rxRNA 63 chemoresistant 63 nanomolar 63 erythropoiesis 63 immunotoxin 63 γ secretase 63 adipogenic 63 telomerase inhibitor 63 antiapoptotic 63 vascular disrupting agents 63 chimeric monoclonal antibody 63 CB2 receptor 63 Anticalins ® 63 tryptase 63 Anticalins R 63 druggable targets 63 novel peptide 63 AT1R 63 PDE# inhibitors 63 S/GSK# 63 nanomolar range 63 pro angiogenic 63 secretory pathway 63 mda 7 63 antiangiogenic 63 siRNA duplexes 63 molecular biomarkers 63 inhibit viral replication 63 Cdc7 63 intercellular signaling 63 JAK#/JAK# 63 preclinically 63 neuronal nicotinic receptors NNRs 63 druggable target 62 GAP #B# 62 plasma pharmacokinetics 62 VDAs 62 peptidic 62 CYT# potent vascular disrupting 62 transgene expression 62 HCV protease inhibitors 62 accumulate preferentially 62 MetAP2 62 coactivators 62 #HT#A 62 non coding RNA 62 outer membrane proteins 62 IL #p# 62 TXNIP 62 VEGF receptor 62 IL 1ß 62 EGFR HER2 62 peptide receptor 62 pleiotropic 62 tumor necrosis 62 GMX# 62 potent antiproliferative 62 selective modulator 62 busulfan 62 orally bioavailable 62 PPARg 62 cytotoxicity assays 62 Treg cell 62 picomolar 62 iNOS 62 novel anticancer 62 tumorigenicity 62 integrin receptors 62 immunomodulation 62 adenoviral 62 kinase inhibition 62 pan HDAC inhibitor 62 protein tyrosine phosphatases 62 proteins peptides 62 mitochondrial toxicity 62 FGFR 62 apoptotic pathway 62 inhibit angiogenesis 62 Hsp# inhibition 62 neurotrophic 62 endothelial activation 62 investigational therapies 62 MTT assay 62 EpCAM 62 NF kappaB activation 62 antiproliferative 62 biodistribution 62 pharmacodynamic effects 62 diagnostic biomarkers 61 tumor subtypes 61 Hedgehog inhibitor 61 apoptosis inducing 61 glycosylated 61 FGFs 61 PDGFR 61 neoplastic 61 protein tyrosine phosphatase 61 microsomal 61 IAP inhibitor 61 interleukin IL -# 61 osteoblastic 61 intracellular protein 61 cisplatin resistant 61 HER2 receptor 61 CCX# 61 vitamin D analogs 61 lytic 61 tubulin binding 61 Immunohistochemical analysis 61 pharmacodynamic endpoints 61 small molecule agonists 61 beta amyloid peptide 61 pharmacokinetic parameters 61 EGFR HER 61 diagnostic biomarker 61 druggable 61 OMP #M# 61 molecularly targeted 61 allosteric 61 XL# inhibits 61 potent inhibition 61 NSCLC tumors 61 Aurora kinase 61 dose proportionality 61 replicon 61 DNA gyrase 61 pharmacodynamic parameters 61 metabolomic profiles 61 FLT3 61 proapoptotic 61 vivo potency 61 ganaxolone 61 selectively inhibited 61 liposomal formulations 61 potent anticancer 61 amplicons 61 Gleevec resistant 61 immuno modulatory 61 FGFR1 61 PI3K Akt 61 AMPK activators 61 carcinoembryonic antigen 61 phosphate S1P 61 Cyclin E 61 inhibit replication 61 H#K#me# 61 endogenous ligands 61 tubulin inhibitor 61 Flt3 61 MAPK pathway 61 carbohydrate polymer 61 HuLuc# 61 antisense inhibitor 61 pharmacokinetic interactions 61 c MET 61 Interferon alpha 61 pharmacodynamic markers 61 amyloidogenic 61 humanized monoclonal antibodies 61 colon carcinoma 61 LTB4 61 IKKß 61 isotype 61 immunological responses 61 cMET 61 JAK inhibitors 61 uricase 61 Cytotoxic 61 EGF receptor 61 CD# expressing 61 tumor specific antigen 61 JAK2 inhibitor 61 polyamine 61 immune stimulatory 61 favorable pharmacokinetic 61 florbetaben 61 biomarker identification 61 chemosensitivity 61 specific lectin receptors 61 ALK inhibitors 61 anticancer therapeutics 61 selective agonists 61 SCD1 61 infected macrophages 61 tumor antigens 61 anti angiogenic agents 61 HCV protease 61 Wnt signaling pathway 61 deacetylase inhibitors 61 inhibiting tumor 61 Azedra 61 Fibroblast Growth Factor Receptor 61 cleavable linker 61 antiproliferative activity 61 muscarinic 61 NK1 61 gastrointestinal stromal tumors GISTs 61 DACH platinum 61 histone deacetylase HDAC 60 intestinal mucosal 60 rxRNA 60 thrombin receptor 60 p# activation 60 eotaxin 60 peptidomimetic 60 therapeutic monoclonal antibody 60 Upregulation 60 biologic therapeutics 60 mononuclear 60 antitumor 60 pharmacodynamic PD 60 neuroprotective properties 60 epithelial tumors 60 somatostatin receptors 60 motexafin gadolinium 60 kidney urologic 60 proprietary polysaccharide 60 Immunotherapeutic 60 pharmacologically relevant 60 lesional 60 phenotyping 60 Th2 cytokines 60 serum PTH 60 receptor subtypes 60 serum antibodies 60 nucleolin 60 CDK inhibitor 60 neuronal signaling 60 CD#b 60 Eg5 60 GSK3B 60 β amyloid 60 radiolabeled 60 NeoLipid TM 60 cyclic AMP cAMP 60 FGFR3 60 Nanobodies 60 PPARgamma 60 ligand TRAIL 60 immune modulatory 60 antiangiogenic activity 60 acadesine 60 HSP# inhibitors 60 non nucleoside 60 proinflammatory mediators 60 Fas ligand 60 investigational humanized monoclonal antibody 60 treating neuropathic pain 60 monoclonal anti 60 siRNAs targeting 60 mTOR signaling 60 intratumoral 60 costimulation 60 osteogenic 60 methylated DNA 60 immunomodulatory 60 DNA intercalator 60 miRs 60 isotypes 60 sCD# 60 myeloma cells 60 TLR8 60 #T# L1 60 pathophysiological effects 60 C5aR 60 serine protease 60 potently inhibit 60 Abeta peptide 60 soluble receptor 60 mutated K ras 60 NS5A 60 Oncogenic 60 M2 subunit 60 sigma receptor 60 acetylcholinesterase AChE 60 novel immunotherapeutic 60 iRGD 60 novel VDA molecule 60 mTOR inhibitors 60 anticancer activity 60 alpha#beta# 60 somatostatin 60 DAVANAT 60 PI3K AKT 60 ARIKACE ™ 60 CCR2 60 antiangiogenic agent 60 plasma lipid 60 AKT inhibitor 60 stem cell pluripotency 60 mitotic progression 60 cytolytic 60 selective inhibition 60 vWF 60 Kahalalide F 60 FGFR4 60 ESBA# 60 vivo RNAi 60 PEGPH# 60 receptor inhibitor 60 NMDA antagonists 60 inhibit EGFR 60 protein kinase C 60 HQK 60 protein secretion 60 JAK2 enzyme 60 PRTX 60 cathepsins 60 prostanoid 60 Symadex 60 cardiotoxic 60 small molecule tyrosine 60 HIV protease 60 chemokine receptor 60 heterologous 60 sd rxRNA compounds 60 SIRT2 60 bispecific antibody 60 highly immunogenic 60 binding affinities 60 Virulizin ® 60 IgG antibodies 60 glucagon receptor 60 redox active 60 synthetic peptides 60 HMG CoA reductase 60 retaspimycin 60 beta interferons 60 proliferative disorders 60 synthetic retinoid 60 histone deacetylases 60 Nanobodies ® 60 sGC 60 small molecule activator 60 amyloid formation 60 5 HT2C receptor 60 CXCR4 receptor 60 glycan structures 60 tolerogenic 60 acetylcholine receptor 60 myofibroblasts 60 deacetylation 60 TTR gene 59 bispecific 59 branching morphogenesis 59 lymphotoxin 59 synovial cells 59 KSP inhibitor 59 interferon IFN 59 molecular abnormalities 59 cathepsin B 59 keratinocyte 59 Osteopontin 59 ERK1 2 59 Pathway Inhibitor 59 vinca alkaloid 59 survivin 59 peptide hormone 59 aberrantly activated 59 induce apoptosis 59 recombinant antibodies 59 gamma secretase inhibitor 59 #ME# 59 PBMCs 59 neoplastic transformation 59 mediated inhibition 59 gp# protein [002] 59 ERK pathway 59 antagomirs 59 thymidylate synthase TS 59 HbF 59 proteoglycan 59 CanAg 59 Multimeric 59 xenograft 59 Orally administered 59 phosphorylated proteins 59 Nanobody ® 59 LSD1 59 NKX#.# 59 osteoclast 59 assay detects 59 antisense inhibitors 59 potent antitumor 59 sphingolipid 59 β catenin 59 nicotinic acetylcholine receptor 59 TG# [003] 59 tyrosine kinase receptor 59 liposomal formulation 59 NS4A 59 Pim kinases 59 MIF protein 59 Aâ 59 HepG2 cells 59 MAb 59 fusion enhancers 59 tumor antigen 59 NNRs 59 Tyrima 59 CDK4 59 radionuclide therapy 59 radiolabelled 59 Lp PLA 2 59 hypermethylated 59 oxysterols 59 thromboxane A2 59 personalized immunotherapy 59 COX enzymes 59 isoform selective 59 vivo validation 59 galectins 59 trans splicing 59 mTOR inhibition 59 matrix metalloproteinases 59 substrate specificity 59 HSP# inhibitor 59 PK PD 59 immunogens 59 cyclic adenosine monophosphate cAMP 59 cerebrospinal fluid CSF 59 antiangiogenic agents 59 serine threonine 59 MTP inhibitor 59 S6K 59 oncoproteins 59 activin 59 IFN g 59 eIF4E 59 monomeric 59 intra tumoral 59 hENT1 59 miRNA expression 59 Pyridorin 59 short hairpin RNAs 59 oligomerization 59 potency selectivity 59 PDGF receptor 59 anti angiogenic agent 59 cytotoxic therapies 59 monoclonal antibody mAb 59 intracellular signal transduction 59 nanocarrier 59 antitumor effects 59 chlamydial 59 macromolecular complexes 59 circulating endothelial cells 59 p# Shc 59 LNP formulations 59 protein tyrosine kinase 59 binding affinity 59 intracellular bacteria 59 Src inhibitors 59 peptide conjugated 59 efflux pump 59 siRNA therapeutic 59 glycolipids 59 NR2B subunit 59 anti miRs 59 anti tumoral 59 androgen receptor AR 59 anti secretory 59 MGd 59 TNFR 59 constitutively expressed 59 CD#c 59 microarray experiments 59 Interferon beta 59 enzyme beta secretase 59 plasma kallikrein 59 lysophosphatidic acid LPA 59 tumor hypoxia 59 multitargeted 59 dimeric 59 vascular endothelial cells 59 VEGF receptors 59 NS#/#A protease 59 mRNA expression 59 Anticalins 59 HIF 1a 59 preclinical efficacy 59 K ras mutations 59 leukemic cell 59 nucleotide analogs 59 MMP inhibitors 59 GRNVAC1 59 anti angiogenic drugs 59 cystatin 59 norepinephrine reuptake inhibition 59 HIF PH 59 carbohydrate polymers 59 aurora kinase 59 Neulasta ® 59 hERG 59 antisense molecules 59 mycobacterial 59 vasoactive 59 BCL2 59 Annexin V 59 dimensional nanostructures 59 polypeptides 59 Blinatumomab 59 upregulates 59 neurite outgrowth 59 ischemic tissues 59 colorectal tumor 59 fluorescent quantum dots 59 MMP2 59 oncogenic transformation 59 coagulation cascade 59 SGLT2 inhibitors 59 pDCs 59 inflammatory cytokine 59 synthases 59 humoral responses 59 targeted antifolate 59 MDSCs 59 glucocorticoid receptors 59 cyclin E 59 therapeutically useful 59 isoprenoid 59 RNAi therapeutic targeting 59 depsipeptide 59 TLR antagonists 59 transferrin receptor 59 IGF IR 59 MDR1 59 Receptors GPCRs 59 RAS RAF MEK 59 administered intraperitoneally 59 synthase TS 59 MEK ERK 59 Rap1 59 TLR agonists 59 liposome encapsulated 59 cytokine receptors 59 perivascular 59 Galectins 59 clinically validated targets 59 miRNA biomarkers 59 TGF β 59 mGluR2 NAM 59 coexpression 59 IMPDH 59 hypoxic tumors 59 5 HT2A 59 pertussis toxin 59 trimeric 59 potent suppressor 59 alkylating 59 gene loci 59 protein homeostasis 59 haematologic 59 syngeneic 59 mGluR5 antagonist 59 FKBP# 59 small molecule activators 59 transient receptor 59 Panzem R NCD 59 IntroductionThe 59 lysosomal 59 ligand induced 59 cyclooxygenase COX 59 microglial activation 59 microtubule inhibitor 59 gene rearrangements 59 HIF 1α 59 MEK inhibitors 59 SERCA2a 59 factor TNF 59 carbohydrate antigens 59 vitro cytotoxicity 59 AAG geldanamycin analog 59 subtype selective 59 osteoblast 59 humanised antibody 59 oral prodrug 59 antiangiogenesis 59 safety tolerability pharmacokinetic 59 Nedd4 59 BRAF kinase 59 Anticalin ® 59 pleiotropic effects 59 tyrosine phosphorylation 59 lentiviral vectors 59 PKCi 59 lymphoid cells 59 5 HT4 receptor 59 triphendiol 59 M1 muscarinic 59 Anticalin 59 CCR9 59 inverse agonist 59 PC# cells 59 aromatase enzyme 59 cytokine secretion 59 prognostic marker 59 clinically relevant 59 serine proteases 59 FK# 59 c MYC 59 protein biosynthesis 59 intracellular proteins 59 mitogen activated protein kinase 59 neuromuscular junction 59 secreted proteins 59 HDACi 59 therapeutic monoclonal antibodies 59 beta1 integrin 59 Enzastaurin 59 etiologic 59 TRAIL induced apoptosis 59 indibulin 59 hedgehog pathway 58 xenograft models 58 anionic backbone 58 mitogenic 58 adenoviral vectors 58 SERMs 58 splice variant 58 XmAb# 58 MET amplification 58 glutamate receptors 58 SSc 58 RRM1 58 EphA2 58 glycosylation profile 58 neurotrophic factors 58 cAMP signaling 58 neuroinflammatory 58 orally dosed 58 peptides proteins 58 nucleoside 58 experimental autoimmune encephalomyelitis 58 Abeta# 58 metastatic neuroendocrine tumors 58 costimulatory 58 Antiangiogenic 58 histologies 58 ubiquitin ligases 58 ISF# 58 isoenzyme 58 EGFR pathway 58 Clusterin 58 direct thrombin inhibitors 58 biomarker assay 58 physico chemical properties 58 FUS1 58 UsiRNAs 58 pyrimidine 58 5 HT2A inverse 58 radiolabeled TM# 58 alpha#beta# integrin 58 cytotoxic 58 dimerization 58 selectively inhibit 58 serine threonine kinase 58 targeting CD# 58 β1 58 E#F# 58 Lixivaptan 58 silencing RNAs 58 p# subunit 58 antiangiogenic therapy 58 HBV replication 58 monocytes macrophages 58 thermosensitive 58 intranasal delivery 58 c myb 58 trophoblast cells 58 antineoplastic 58 Enkephalin 58 FasL 58 p# inhibitor 58 ErbB3 58 neovascular 58 eicosanoid 58 MAP kinase 58 lymphoid tissues 58 pharmacodynamic profile 58 MAPK signaling pathway 58 clusterin protein 58 lymphoid organs 58 hypoxia inducible factor 58 5 HT2A receptor 58 WT1 58 transfected cells 58 TNFalpha 58 Tissue Factor 58 p# mutations 58 Kinoid 58 beta amyloid peptides 58 mesothelin 58 EGF receptors 58 induces apoptosis 58 systemically administered 58 B7 H3 58 radiosensitivity 58 HIF PH inhibitors 58 NKG2D 58 CoVal TM fusion 58 mAbs 58 bleomycin 58 dasatinib Sprycel 58 CXCR7 58 HCV replication 58 cationic lipid 58 MMP9 58 antifibrotic 58 APOPTONE 58 CCR9 antagonist 58 aT cell 58 Histone deacetylase 58 Aldosterone 58 small molecule inhibitors 58 mimetic compounds 58 paxillin 58 predictive biomarker 58 Trofex 58 histone deacetylase 58 EP1 receptor 58 aurora kinase inhibitor 58 5 HT2A serotonin 58 P cadherin 58 PEG SN# 58 lactate dehydrogenase 58 #beta estradiol 58 PTPN# 58 potent antitumor activity 58 CBLC# 58 ABCB1 58 serotonin receptor 58 inhibit metastasis 58 MCF7 58 predictive biomarkers 58 HEK# cells 58 RNA polymerases 58 AV HALT 58 lipid soluble 58 VE cadherin 58 multiplex assay 58 gastric carcinomas 58 lactate dehydrogenase LDH 58 synthetic lethality 58 elastase 58 Darinaparsin 58 chemotherapeutics 58 genetic loci 58 prostate carcinoma 58 PIK3CA 58 ADAMTS# 58 degranulation 58 downstream effectors 58 myeloproliferative disorders 58 apolipoproteins 58 HepDirect prodrug 58 unconjugated 58 phosphoprotein 58 obatoclax 58 Fc receptors 58 vidofludimus 58 Factor Receptor 58 #S subunit 58 genomic biomarker 58 virulence genes 58 Akt activation 58 soluble CD# 58 hepatoma 58 mitotic kinesin 58 Sudhir Agrawal D.Phil 58 physiologically relevant 58 monoclonal antibodies mAbs 58 equimolar 58 erythropoietic 58 immunofluorescence microscopy 58 immunomodulatory effects 58 V#F mutation 58 synthetic siRNA 58 MUC1 58 CagA 58 mertansine 58 sphingomyelin 58 IFN γ 58 aberrant activation 58 cytokine signaling 58 lymphangiogenesis 58 targeted radiotherapeutic 58 benzimidazole 58 Tumor Response 58 PKC isoforms 58 vitro assay 58 alpha7 NNR 58 verteporfin 58 dAbs 58 neovascularization 58 inhibit tumor angiogenesis 58 Histone 58 Factor VIIa 58 P#X# 58 Archexin 58 PSMA ADC 58 effector protein 58 HER2 receptors 58 drug zotarolimus 58 rhITF 58 VEGF inhibitors 58 nonnucleoside reverse transcriptase inhibitors 58 JAK1 58 potently inhibits 58 T#M 58 linear pharmacokinetics 58 mRNA molecules 58 Phylomer ® 58 HER2 neu 58 Immunohistochemical staining 58 miR #a [001] 58 beta subunit 58 Cardiotoxicity 58 toxic beta amyloid 58 proto oncogene 58 TNFα 58 radezolid 58 DiLA2 liposomes 58 hA# 58 dopamine transporter 58 nucleoside analogues 58 irreversible inhibitor 58 Methotrexate MTX 58 HSP# 58 P gp 58 tetramer 58 colorectal carcinogenesis 58 PI3K inhibitor 58 procaspase 3 58 resistant mutants 58 metaplasia 58 glucokinase 58 HDAC 58 hypericin 58 BAL# [002] 58 cyclophilin inhibitor 58 potent anti angiogenic 58 prostaglandin synthesis 58 delafloxacin 58 transgenic mouse models 58 atherothrombotic 58 micro RNAs 58 BNC# 58 Neuropeptide Y 58 Cloretazine R 58 bortezomib Velcade 58 orally bioavailable mimics 58 mTOR signaling pathway 58 sortilin 58 TLR9 agonist 58 ovarian carcinoma 58 plasma lipoprotein 58 transgenic rats 58 partial agonist 58 RANTES 58 galectin 58 ErbB3 HER3 58 LDL receptor 58 inhibits VEGF 58 favorable tolerability 58 neuronal dysfunction 58 p#/CBP 58 Fc receptor 58 anti neoplastic 58 recombinant antibody 58 stimulate insulin secretion 58 HGS ETR2 58 IgG1 antibody 58 intracellular signaling pathways 58 Leydig cell 58 biochemical abnormalities 58 fibrotic disease 58 Triapine R 58 biologic pathways 58 nucleoside analogs 58 messenger ribonucleic acid 58 anti amnesic 58 eIF 4E 58 protein ligand 58 phage display libraries 58 rxRNA compounds 58 flavopiridol 58 CLL cells 58 peripheral blood mononuclear 58 vitamin D receptors 58 B7 H4 58 EGFr 58 FGFR2 58 oxidative stress inducer 58 cell lysis 58 thrombogenic 58 antisense inhibition 58 neurogenic 58 poly ADP ribose polymerase 58 beta globin gene 58 S#P# 58 mitochondrial respiration 58 p# biomarker 58 immunostaining 58 viral proteins 58 Glycosylation 58 CCL# 58 antitumor effect 58 HMGCR 58 endostatin 58 hematopoiesis 58 Nav#.# 58 optical biosensors 58 isatoribine 58 multiplexed assays 58 molecular determinants 57 tumor microenvironment 57 macrolide antibiotic 57 prognostic biomarker 57 affinity ligands 57 PhG alpha 1 57 gastric carcinoma 57 Epidermal Growth Factor Receptor 57 glucocorticoid receptor 57 synthetic analogues 57 Xanafide 57 TLR9 agonists 57 immunostimulatory 57 Thiovir 57 Onconase 57 #ß 57 histone deacetylase HDAC inhibitor 57 NTDDS 57 papillary renal cell carcinoma 57 RezularTM 57 Sphingomab 57 imetelstat 57 viral kinetics 57 glycopeptides 57 VTAs 57 phosphorylated tau 57 ENaC 57 Akt inhibitor 57 siRNA knockdown 57 hapten 57 HCV polymerase 57 PPARγ 57 PDE# 57 antibody mediated 57 cytotoxicity 57 neuro protective 57 CEACAM1 57 selective kinase inhibitor 57 ZFP TF 57 Cathepsin B 57 amyloid beta peptides 57 Tumor Necrosis Factor 57 endothelin receptors 57 SIRT1 enzyme 57 AtherOx 57 macrophage inflammatory 57 PKC inhibitors 57 gene inactivation 57 myelofibrosis polycythemia vera 57 ETBs 57 proteasome inhibitor 57 pharmacodynamic biomarkers 57 NEUGENE antisense 57 antisense oligonucleotides