Related by context. Frequent words. (Click for all words.) 61 dietary restriction 56 caloric restriction 54 calorie restriction 53 Caenorhabditis elegans 53 roundworms 50 Drosophila melanogaster 49 low calorie diets 49 roundworm 48 fruit fly Drosophila 48 sirtuin 48 receptor protein 48 Wolbachia 47 fruit flies 47 Fruit flies 46 C. elegans 46 telomere 46 resveratrol 45 telomere length 45 Telomerase 45 telomerase activity 45 lifespan 45 mammalian 45 telomeres 44 ApoE4 44 mitochondrial function 44 mice 44 tumor suppressing 44 telomere shortening 44 HHMI investigator 44 APOE4 44 calorie diets 44 Wnt signaling 44 genetically altered mice 43 sirtuins 43 MicroRNA 43 Drosophila 43 lifespans 43 genetic variability 43 neurogenesis 43 regulate gene expression 43 curcumin 43 mammalian cells 42 hepatocyte 42 cardio protective 42 sulforaphane 42 enzyme telomerase 42 hormone leptin 42 reproductive hormones 42 spermatogenesis 42 FGF# 42 rhesus monkeys 42 SIRT1 42 calcium absorption 42 genetic alteration 42 cell signaling pathways 42 adiponectin 42 STAT3 41 Astaxanthin 41 cultured cells 41 PGE2 41 Zebrafish 41 mammals 41 herpes viruses 41 neurodegeneration 41 Bt toxin 41 Plasmodium 41 embryogenesis 41 malignant transformation 41 estrogen receptors 41 mammalian brain 41 Hedgehog pathway 41 nicotinamide 41 Nrf2 41 cognitive function 40 zebrafish 40 metabolic 40 olfaction 40 biochemical processes 40 Help Reason 40 PPAR gamma 40 imprinted genes 40 Aedes aegypti 40 nonsense mutation 40 reproductive biology 40 homologous recombination 40 metabolic processes 40 stem cell differentiation 40 signaling molecule 40 mitochondrial genome 40 aneuploidy 40 ferritin 40 signaling pathway 40 thyroid function 40 p# gene 40 lectin 40 humans 40 NKT cells 40 Arabidopsis 40 circadian clock 40 brain plasticity 40 astrocyte