Related by context. All words. (Click for frequent words.) 67 alpha synuclein 66 amyloid 66 tau protein 63 beta amyloid 63 amyloid beta 63 amyloid plaques 62 Aβ 62 neurofibrillary tangles 62 gamma secretase 62 beta amyloid plaques 62 protein tau 62 beta catenin 62 mutant protein 61 beta amyloid peptide 61 tumor suppressor protein 60 apoE 60 tau proteins 60 BACE1 59 amyloid beta peptides 59 MDM2 59 clusterin 59 SOD1 59 progranulin 59 Abeta 59 oncoprotein 58 Pin1 58 protein kinase C 58 Akt 58 amyloids 58 E cadherin 58 mitochondrial respiration 58 Aß 58 EZH2 58 amyloid beta peptide 58 amyloid peptides 57 PrP 57 caspases 57 phosphorylation 57 amyloid beta proteins 57 mutant huntingtin 57 LRRK2 57 glial 57 amyloid plaque 57 amyloid beta plaques 57 enzymatic activity 57 phosphorylated tau 57 ENaC 57 calpain 57 protein kinase 57 FGF2 57 protein fragment 57 neurodegeneration 57 BMP signaling 57 catenin 57 SGK1 57 NMDA receptor 57 mitogen activated protein kinase 57 amyloid β 57 NMDA receptors 57 presenilin 57 tau tangles 57 TGF beta 57 S#A# [002] 57 GAPDH 57 WT1 57 genes encoding 57 RANKL 57 secretase 57 Src 57 LRP6 56 survivin 56 huntingtin protein 56 tyrosine 56 mutated protein 56 hypermethylation 56 vimentin 56 amyloid peptide 56 amyloid beta protein 56 glutamate 56 integrin 56 Wnt signaling 56 amyloid protein 56 dimers 56 ERK2 56 dystroglycan 56 mutant proteins 56 CatB 56 Abeta# 56 astrocytes 56 heterodimers 56 TNFalpha 56 CaMKII 56 β amyloid 56 β catenin 56 glutamate receptor 56 NR2B 56 glycoproteins 56 ADDLs 56 NF kB 56 morphogen 56 c myc 56 caspase activation 56 senile plaques 56 insulin secretion 56 amyloid deposits 56 ubiquitination 56 RhoA 56 paxillin 56 overexpression 56 misfolded 55 PPAR gamma 55 Skp2 55 amyloid proteins 55 cAMP 55 SIRT1 55 activin 55 estrogen receptor alpha 55 PDGFR 55 phosphorylated 55 Cdc# 55 FAK 55 apoE4 55 synaptogenesis 55 calcium homeostasis 55 glutamate receptors 55 acetylcholine 55 fatty acid synthase 55 BDNF 55 cyclins 55 amyloid fibrils 55 neuronal cell 55 MEF2 55 LIS1 55 SIRT6 55 GRK2 55 histone 55 neuronal 55 pRb 55 MAO B 55 caveolin 1 55 MAPK 55 p# [001] 55 Cyclin D1 55 PIP3 55 ER alpha 55 osteopontin 55 proto oncogene 55 cyclin B1 55 micro RNAs 55 apoptotic 55 signaling molecule 55 ABCA1 55 PIP2 55 paracrine 55 microglial cells 55 c MYC 55 cystine 55 toxic amyloid beta 55 tumor suppressor genes 55 transcriptional repressor 55 DARPP 55 neuronal cells 55 androgen receptor 55 serotonin transporter 55 mRNA 55 gene encoding 54 signaling pathway 54 ACh 54 ganglioside 54 ERK1 2 54 intracellular 54 SH2 B 54 osteocalcin 54 p#Kip# 54 progerin 54 Smad3 54 huntingtin 54 miR 54 homodimers 54 renal fibrosis 54 miR# 54 ERK signaling 54 dopamine signaling 54 autophagic 54 HOTAIR 54 reductase 54 methylation 54 FTLD 54 nestin 54 Rac1 54 cellular senescence 54 mutant huntingtin protein 54 KEAP1 54 ß amyloid 54 Prox1 54 Wnt 54 acetyl groups 54 H#K# [002] 54 cell signaling pathways 54 Mcl 1 54 osteoclast 54 LDL receptor 54 GSK3 54 proteins 54 cytochrome c 54 FGFR1 54 low density lipoproteins 54 SORL1 54 cadherin 54 IL 1beta 54 tau aggregates 54 SOD1 protein 54 regulated kinase ERK 54 glycosylation 54 DNMT1 54 PTEN protein 54 cardiolipin 54 parkin 54 DISC1 54 metabolic enzymes 54 Htt 54 amyloid precursor protein 54 neurofilament 54 mitochondrial function 54 CEACAM1 54 ceramide 54 intracellular signaling 54 MAP kinase 54 beta amyloid proteins 54 Aâ 54 transthyretin 54 MMPs 54 Notch signaling 54 synuclein 54 Sox# 54 tumorigenesis 54 E#F# 54 serine protease 54 TGF b 53 Nrf2 53 Hedgehog signaling 53 sortilin 53 transcriptional activation 53 Sonic hedgehog 53 sarcosine 53 MMP# 53 endoplasmic reticulum 53 LKB1 53 astrocyte 53 mRNA expression 53 Notch1 53 TGF β 53 oligomers 53 NFkB 53 Hh 53 MAPK pathway 53 inhibitory 53 cyclin D1 53 mRNAs 53 chaperone protein 53 protein beta amyloid 53 p# MAPK 53 cyclin 53 tau phosphorylation 53 MeCP2 53 NAD + 53 STAT1 53 phenotype 53 ferritin 53 Foxp3 53 dopaminergic neurons 53 microglial 53 c Src 53 tyrosine kinase 53 protein synthesis 53 polyamine 53 S#K# 53 GATA3 53 postsynaptic 53 Rap1 53 antioxidant enzyme 53 caveolin 53 TrkB 53 heterochromatin 53 neuropeptide Y 53 myelination 53 osteoblast 53 PGE2 53 tumor suppressor 53 TLR4 53 carcinoembryonic antigen 53 proteasome 53 leptin 53 beta1 integrin 53 Wnt pathway 53 soluble fms 53 miRNAs 53 cohesin 53 ApoB 53 JAK2 53 p# protein 53 molecular pathway 53 motor neuron degeneration 53 synapse formation 53 STAT3 53 GTPase 53 adhesion molecule 53 ncRNAs 53 Clusterin 53 VEGF receptor 53 FGF# 53 GRP# 53 fascin 53 uPAR 53 Rho kinase 53 SIRT3 53 tumor suppressor gene 53 superoxide dismutase 53 Purkinje cells 53 nNOS 53 miR #a [002] 53 p# activation 53 IKKß 53 GPR# [002] 53 serotonin receptor 53 neuronal degeneration 53 histone acetylation 53 synaptic 53 nicotinic receptors 53 calmodulin 53 encodes protein 53 Bcl xL 53 cytoplasmic domain 52 mTOR 52 neuronal dysfunction 52 MT1 MMP 52 NFAT 52 SUMOylation 52 aP2 52 telomeric 52 cell adhesion 52 beta amyloid peptides 52 TAp# 52 PTEN gene 52 lipofuscin 52 cAMP signaling 52 tubulin 52 androgen receptor AR 52 estrogen receptor 52 ubiquitylation 52 osteoclast activity 52 caveolae 52 calcineurin 52 globin 52 AMPA receptors 52 proteolysis 52 disulfide bond 52 FasL 52 RBP4 52 EGF receptor 52 hippocampal neurons 52 palladin 52 catalase 52 beta amyloid protein 52 Sirt1 52 enzyme 52 cdk5 52 BMP4 52 dentate gyrus 52 UCP1 52 paralogs 52 microRNA molecules 52 polyamines 52 isoform 52 beta subunit 52 TGF ß1 52 noncoding RNAs 52 ras gene 52 protein alpha synuclein 52 PGC 1α 52 tyrosine phosphatase 52 MMP9 52 molecule 52 HDAC2 52 IRF5 52 mitochondrial fusion 52 lipids 52 NKG2D 52 aromatase 52 prion protein 52 Kv#.# 52 atherogenesis 52 utrophin 52 PCSK9 52 Pax6 52 nAChR 52 mice lacking 52 receptor 52 microglial activation 52 epigenetic alterations 52 telomere shortening 52 JAK2 enzyme 52 PGC1 52 cofilin 52 Dpp 52 Myc 52 alpha synuclein protein 52 plasminogen 52 adiponectin 52 brain derived neurotrophic 52 neuroligin 52 OGG1 52 ApoE4 52 ncRNA 52 eNOS 52 hypocretin 52 gene p# 52 isoforms 52 nuclei 52 myelin 52 glucocorticoid 52 PAK1 52 microRNAs 52 glucocorticoid receptor 52 histone modifications 52 neurofibrillary 52 FANCD2 52 senescent cells 52 epigenetic silencing 52 ERK pathway 52 E3 ligase 52 fibrils 52 vascular endothelial cells 52 microRNA 52 amyloid deposition 52 actin cytoskeleton 52 FOXO1 52 phagocytosis 52 TNFα 52 excitotoxicity 52 toxic beta amyloid 52 arginase 52 Cdk5 52 Wnt1 51 matrix metalloproteinase 51 protein clumps 51 IFNg 51 lysosomal 51 ADAM# 51 Schwann cells 51 ERK 51 γ secretase 51 melanocyte 51 XBP1 51 c Myc 51 TRPV3 51 CDK8 51 cytokine 51 Alzheimer disease pathology 51 ubiquitin ligase 51 Hsp# [001] 51 neurofibromin 51 immunological synapse 51 nitrotyrosine 51 TMEM#B 51 oncogenic 51 casein kinase 51 dopamine receptor 51 UCP2 51 nicotinic receptor 51 DLC1 51 autocrine 51 protein 51 coding RNA 51 DNA methylation 51 TGF beta pathway 51 transgenic mouse model 51 Smoothened 51 iNOS 51 CXCL# 51 HPA axis 51 HMG CoA reductase 51 JAK STAT 51 fibrogenesis 51 GluR1 51 tyrosine phosphorylation 51 phagocyte 51 transgene expression 51 neuromuscular junction 51 adhesion molecules 51 phenylalanine 51 neurite outgrowth 51 bone resorption 51 beta globin 51 Rab5 51 deacetylation 51 SNAREs 51 Th2 51 Brain derived neurotrophic 51 dopamine neurons 51 dopamine transporter 51 cellular metabolism 51 p#NTR 51 fatty acid synthesis 51 DLX5 51 angiotensin II 51 serotonin 51 transcriptional repression 51 Runx2 51 axon guidance 51 IKK2 51 interneurons 51 gene encodes protein 51 KLF2 51 cyclic AMP 51 ectopic expression 51 Vpu 51 Stat3 51 dynamin 51 synaptic function 51 platelet aggregation 51 GSK 3ß 51 constitutively 51 actin 51 lipoprotein 51 PKM2 51 superoxide 51 galanin 51 IGFBP2 51 PI3K 51 hepatocyte growth 51 chromatin structure 51 Alu RNA 51 peroxisome 51 NKCC1 51 VE cadherin 51 B7 H3 51 mesenchymal cells 51 mitochondria 51 dephosphorylation 51 extracellular signal 51 caspase 51 Th1 cells 51 BRAF protein 51 adipogenesis 51 hyperactivation 51 HSF1 51 cell motility 51 molecular mechanism 51 5 HT1A 51 HIF 1a 51 F actin 51 Sirt3 51 podocytes 51 beta adrenergic receptors 51 protein p# 51 NHEJ 51 VEGFR1 51 hedgehog signaling 51 estrogen receptors 51 E selectin 51 ErbB4 51 presynaptic 51 PTPN# 51 amyloid ß 51 prion proteins 51 neurotransmitter acetylcholine 51 NF κB 51 PINK1 51 Notch receptor 51 insulin receptors 51 triacylglycerol 51 ß catenin 51 FOXP3 51 Cyclin E 50 chaperone proteins 50 piRNAs 50 cytosolic 50 cholesterol metabolism 50 KLF4 50 glutamatergic 50 tenascin C 50 PTP1B 50 mitochondrial dysfunction 50 NF kappa B 50 phosphatase 50 acinar 50 D2 receptors 50 kinase domain 50 chromosomal instability 50 overactivation 50 TRAF6 50 sphingolipid 50 focal adhesion kinase FAK 50 alpha subunit 50 proinsulin 50 neuroligins 50 suppressor gene 50 tumor cells 50 transgenic mice 50 HSP# 50 IGF2 50 circadian clock genes 50 tumor suppressor p# 50 MECP2 50 fibrous tangles 50 TSLP 50 TRF1 50 factor BDNF 50 aldosterone 50 Sgk1 50 neuritic plaques 50 ACE2 50 catabolism 50 tyrosine hydroxylase 50 kinase pathway 50 alanine 50 mutant SOD1 50 Abeta protein 50 protein kinases 50 transcriptional regulation 50 p#INK#a 50 messenger RNA 50 autoantibodies 50 Integrin 50 myogenesis 50 MMP2 50 molecular pathways 50 Dicer 50 guanosine 50 TFIIH 50 Siglec 8 50 Wnt#b 50 IL 1ß 50 amyloid formation 50 TGFb 50 MAPKs 50 TSP1 50 lysosome 50 apoptotic pathway 50 miR #a [001] 50 thioredoxin 50 inflammatory cytokines 50 gene transcription 50 interleukin 50 #BP# 50 mTORC1 50 LDL cholesterol 50 receptor subunit 50 HSCs 50 opioid receptor 50 Srcasm 50 oligomerization 50 RANK ligand 50 transcriptional regulators 50 mitochondrial 50 Wnt signaling pathway 50 striatal 50 IKKa 50 hedgehog pathway 50 CaM kinase II 50 frataxin 50 cytoskeletal 50 neuregulin 50 transgenic mice expressing 50 SREBP 50 neurogenesis 50 PEDF 50 H#K#me# 50 hepatic stellate cells 50 insulin resistance 50 abnormal tau 50 RASSF1A 50 Sp1 50 PKD1 50 aberrantly 50 cell adhesion molecules 50 neuropeptide Y NPY 50 cyclic GMP 50 morphogens 50 FOXO3a 50 neurotransmitter 50 Caspase 50 Fig. 1C 50 membrane fusion 50 focal adhesions 50 DNA methylation patterns 50 menin 50 polypeptide 50 biochemically 50 OPHN1 50 TrkA 50 demethylation 50 gene 50 acetylcholine receptors 50 proteases 50 misfolding 50 goblet cells 50 vWF 50 furin 50 oxidative phosphorylation 50 neuronal function 50 receptor gene 50 germ cells 50 granule cells 50 beta catenin protein 50 Nf1 50 SIRT2 50 APOE gene 50 neurones 50 AMPA receptor 50 NRG1 50 chemokine receptor 50 Frizzled 50 Wnt proteins 50 receptor signaling 50 fatty acid oxidation 50 MyoD 50 TORC2 50 amyloid protein plaques 50 amyloid fibers 50 overexpressing 50 neuronal plasticity 50 HGF 50 Ca2 + 50 mitochondrial membrane 50 FMRP 50 hepcidin 50 CHD7 50 TGF ß 50 cholinergic 50 interferon pathway 50 XPB 50 gluconeogenesis 50 astrocytic 50 adrenergic receptors 50 telomere 50 PON1 50 GABAergic neurons 50 LRP1 50 Wnts 50 microtubules 50 cyclin E 50 LRP5 50 myosin 50 RUNX3 50 serotonin signaling 50 pancreatic islet 50 LDL receptors 50 c Fos 50 kinase enzymes 50 SCD1 50 HtrA2 49 mitochondrial biogenesis 49 protein encoded 49 serine threonine kinase 49 CD#L 49 palmitoylation 49 telomerase activity 49 retinal cells 49 SMN1 49 hsp# 49 p# gene 49 myofibroblasts 49 signaling cascade 49 porphyrins 49 short hairpin RNA 49 HIP1 49 centrosomes 49 isothiocyanates 49 resistin 49 CCN2 49 nerve degeneration 49 myeloma cells 49 evolutionarily conserved 49 cannabinoid receptors 49 molecular 49 TERT 49 gene expression 49 CIB1 49 kalirin 49 acetylation 49 chitinase 49 NF kappaB 49 biogenesis 49 ATPase 49 stromal cells 49 B lymphocytes 49 macrophages 49 interleukins 49 EphB2 49 adipocytes 49 messenger molecule 49 LXRs 49 selenoproteins 49 LDLR 49 KLF# 49 MALAT1 49 PPAR γ 49 endonuclease 49 miRNA expression 49 neurotransmission 49 PTEN 49 neurotransmitter glutamate 49 cell adhesion molecule 49 polyglutamine 49 serum cholesterol 49 c Abl 49 endocannabinoids 49 noncoding RNA 49 PRDM# 49 COX2 49 naturally occurring enzyme 49 glioblastoma cells 49 cellular organelles 49 receptor molecule 49 neuropeptide 49 collagen VI 49 prostaglandin E2 49 fission yeast 49 CFTR protein 49 virulence genes 49 prostaglandin E2 PGE2 49 ghrelin 49 POMC neurons 49 Hcrt 49 vacuolar 49 cypin 49 cryptochrome 49 synaptic plasticity 49 beta amyloid plaque 49 receptors 49 APOE4 49 telomere dysfunction 49 glutamate signaling 49 P cadherin 49 PU.1 49 crystallin 49 synapse maturation 49 myostatin 49 epigenetic 49 cannabinoid receptor 49 estrogen receptor beta 49 neurons 49 dysregulated 49 thyroid hormone 49 macrophage 49 HDAC6 49 FMRP protein 49 Six3 49 nerve cells 49 integrins 49 oxidized phospholipids 49 oxidized LDL 49 normal prion proteins 49 CD1d 49 lipoprotein lipase 49 FoxO1 49 insulin secreting cells 49 adenylate cyclase 49 cystic fibrosis transmembrane conductance 49 transcription factors 49 excitatory neurotransmitter glutamate 49 transcriptionally 49 PKC alpha 49 RNA transcripts 49 fibril 49 metalloproteinases 49 arrestin 49 glycan 49 lipid synthesis 49 Methylation 49 Beta amyloid 49 leptin receptors 49 Th2 cells 49 oxidative damage 49 tRNA synthetase 49 Th1 type 49 microtubule 49 chromosome condensation 49 TGF beta signaling 49 receptor gamma 49 transactivation 49 centromeres 49 biochemical pathway 49 γδ T cells 49 dendritic spine 49 NRF2 49 acetylcholine receptor 49 beta endorphin 49 T lymphocytes 49 atherosclerosis 49 H2AX 49 beta globin gene 49 vesicle 49 lysosomal enzyme 49 lipid peroxidation 49 lipoproteins 49 adult neurogenesis 49 TXNIP 49 genomic instability 49 ARF1 49 GLUT4 49 neurotransmitter GABA 49 malonyl CoA 49 exocytosis 49 forebrain 49 receptor protein 49 estrogen metabolism 49 nAChRs 49 reactive oxygen species 49 cardiac hypertrophy 49 MDSCs 49 sphingolipids 49 arcuate nucleus 48 lymphoid cells 48 glucose metabolism 48 CTGF 48 HGPS 48 amino acid tyrosine 48 TRPV4 48 Sonic Hedgehog 48 CD# ligand 48 acetyl CoA 48 pDCs 48 ciliated 48 glycoprotein 48 IL 1β 48 LTB4 48 apolipoprotein B 48 Lrp5 48 alpha defensins 48 primary cilia 48 histones 48 exon 48 beta amyloid fragments 48 hepatic glucose production 48 elevated homocysteine 48 macrophage infiltration 48 PC# cells 48 glia 48 oncogenic transformation 48 ubiquitin molecules 48 Amyloid plaques 48 GSTT1 48 subunits 48 dopamine receptors 48 VEGF 48 cellular pathways 48 HOX genes 48 costimulatory 48 neuronal stem cells 48 Notch pathway 48 glucokinase 48 DISC1 gene 48 NK cells 48 GABAergic 48 glycosyltransferase 48 RNA splicing 48 receptor tyrosine kinase 48 inflammatory cytokine 48 Pten 48 uPA 48 NPD1 48 BRAF gene 48 sumoylation 48 IRE1 48 membrane protein 48 pyramidal neurons 48 RNA polymerase II 48 avidin 48 regulates gene expression 48 neuroendocrine 48 tumor microenvironment 48 uric acid 48 podocyte 48 gamma oscillations 48 matrix metalloproteinases 48 alternative splicing 48 lymphocytes 48 antigenic epitopes 48 lysosomes 48 NADPH oxidase 48 GABAergic interneurons 48 focal adhesion 48 nucleolus 48 c Myb 48 nitric oxide synthase 48 BCL6 48 polyphenols 48 Nanog 48 intracellular proteins 48 mutant mice 48 Nogo 48 secretion 48 GTPases 48 Akt1 48 constitutively active 48 cathepsins