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(Click for frequent words.) 60 daytime drowsiness 59 Chronic insomnia 59 untreated sleep apnea 57 sleep deprived 57 circadian misalignment 57 Sleepiness 56 Circadian rhythm 56 allostatic 56 overeating 56 untreated OSA 56 circadian rhythms 56 hypersomnia 56 sleep disordered breathing 55 arousals 55 Chronic sleep deprivation 55 sleepiness 55 excessive sleepiness 55 daytime naps 55 Sleep deprivation 55 sleep deprivation 55 restorative sleep 54 hormones leptin 54 chronic migraine headaches 54 undiagnosed sleep apnea 54 sleep hormone melatonin 54 sleep disorders 54 postpartum blues 54 sleep disturbances 54 Yo yo dieting 54 Picky eating 54 Charles Czeisler 54 acne breakouts 53 nighttime heartburn 53 elevated cortisol 53 bruxism 53 PMS symptoms 53 fatigue irritability 53 neuro transmitters 53 Overtraining 53 melatonin supplements 53 spinal misalignment 53 disordered breathing 53 daytime alertness 53 undereating 53 adrenal fatigue 53 carbohydrate cravings 53 ghrelin hormone 53 inattention blindness 53 leptin deficient mice 53 RLS symptoms 53 orexin 52 circadian rhythmicity 52 leptin resistance 52 Stress hormones 52 Secondhand smoke exposure 52 circadian cycle 52 Van Cauter 52 dust mite allergies 52 Disordered eating 52 postural imbalances 52 untreated obstructive sleep 52 Bruxism 52 parasomnias 52 hormone melatonin 52 SRBD 52 OSAHS 52 Sonia Ancoli Israel 52 Daytime sleepiness 52 cortisol hormone 52 RLS sufferers 52 circadian rhythm sleep 52 unhealthy snacking 52 extreme dreaders 52 chronic backache 52 biochemical imbalances 52 inattentional blindness 52 circadian rhythm 52 transient insomnia 52 bladder contractions 52 Sexsomnia 51 serotonin deficiency 51 shiftwork 51 Hyperactivity 51 wakings 51 neuronal plasticity 51 Jeffrey Ellenbogen 51 daytime sleepiness 51 contagious yawning 51 cortisol secretion 51 biochemical imbalance 51 overtired 51 hormones ghrelin 51 hypoglycemic episodes 51 Robert Stickgold 51 frequent awakenings 51 hyperphagia 51 Gangwisch 51 impaired cognition 51 metabolic acidosis 51 depressive moods 51 leptin hormone 51 Disrupted sleep 51 headaches irritability 51 galanin 51 Sleep disturbances 51 muscle dysmorphia 51 monoamine 51 antenatal depression 51 Chervin 51 unrefreshed 51 underactive 51 inconsolable crying 51 Skipping breakfast 51 Calorie restriction 51 vestibular dysfunction 51 leptin deficiency 51 circadian rhythm disorders 51 behavioral disturbances 51 sleeplessness 51 Practicing yoga 51 neurochemistry 51 apneic episodes 51 sleep bruxism 51 basal metabolic rate 50 gastric distension 50 Drowsiness 50 Migraine headaches 50 satiety 50 sleep 50 hormone ghrelin 50 TMJD 50 arrythmia 50 enuresis 50 mindless munching 50 dopamine antagonists 50 compensatory mechanisms 50 Chiara Cirelli 50 neurological degeneration 50 melatonin hormone 50 salivary cortisol 50 syndrome OSAS 50 caloric restriction 50 Bed wetting 50 vagal episode 50 Roenneberg 50 hormonal fluctuations 50 drinking diet sodas 50 apnea OSA 50 Restless legs 50 unpleasant sensations 50 Irritability 50 hypovolemia 50 thermoregulatory 50 underactive thyroid gland 50 hypocretin 50 Bedwetting 50 distractibility 50 neurohormones 50 apnea sufferers 50 nocturnal awakenings 50 Unhealthy lifestyles 50 Physical inactivity 50 androgen depletion 50 Untreated depression 50 metabolic dysfunction 50 reflux symptoms 50 sedentary habits 50 obstructive sleep apnea hypopnea 50 irritability headaches 50 Binge eating 50 synaptic function 50 confusional arousals 50 Excessive sweating 50 involuntary muscle contractions 50 Skipping meals 50 obstructive sleep 50 alexithymia 50 Arnedt 50 irritability depression 50 daytime somnolence 50 insomnia 50 unmeasured factors 50 irritability nervousness 49 enlarged tonsils 49 Essential tremor 49 neurotoxic effects 49 attention-deficit/hyperactivity disorder ADHD 49 vomiting skin rashes 49 untreated ADHD 49 neurochemicals 49 circadian 49 hormone imbalances 49 crave sweets 49 crave carbohydrates 49 brain neurochemistry 49 intermittent hypoxia 49 depressive symptomatology 49 brain shrinkage 49 chemical serotonin 49 carbohydrate craving 49 snoring sleep apnea 49 overexercising 49 Vitamin D insufficiency 49 somatic symptoms 49 unrefreshing sleep 49 neural plasticity 49 Chialvo 49 sleep apnea 49 J. Todd Arnedt 49 sugar cravings 49 PLMS 49 carotid atherosclerosis 49 thyroid hormone levels 49 debilitating headaches 49 drinking caffeinated beverages 49 status epilepticus 49 severe hypoglycaemia 49 gamma oscillations 49 Restless Legs Syndrome RLS 49 hypocretin neurons 49 excessive daytime sleepiness 49 Binge eaters 49 sleep apnea narcolepsy 49 calorically restricted 49 headaches dizziness disorientation nausea 49 wrist actigraphy 49 Hot flushes 49 circadian cycles 49 abnormal rhythms 49 chronic insomnia 49 dopamine signaling 49 suppresses appetite 49 involuntary urination 49 disordered eating patterns 49 FASPS 49 polysomnogram 49 inattention impulsivity 49 Overactive bladder 49 Hormonal imbalance 49 apneas 49 Menstrual cramps 49 estrogen deficiency 49 caloric intakes 49 Robert Vorona 49 Cardiac arrhythmia 49 painful muscle spasms 49 overactivity 49 emotional reactivity 49 amenorrhea 49 telogen effluvium 49 asthmatic symptoms 49 Ancoli Israel 49 night wakings 49 neurotransmitters dopamine 49 insulin resistance 49 airway blockage 49 anxiety irritability 48 hormone prolactin 48 Czeisler 48 sleep deprivation impairs 48 tardive dyskinesia TD 48 neuro physiological 48 Vitamin D deficiencies 48 Insulin resistance 48 Phyllis Zee 48 Strenuous exercise 48 underactive thyroid 48 cognitive 48 temporomandibular disorders 48 extrapyramidal symptoms 48 Ritalin methylphenidate 48 Generalized anxiety disorder 48 hyperexcitability 48 extrapyramidal symptoms EPS 48 drinking beetroot juice 48 hyper excitability 48 mortality salience 48 cortical plasticity 48 fat malabsorption 48 neurotransmitter GABA 48 pharmacological interventions 48 recurrent abdominal pain 48 Teeth grinding 48 Sleeping pills 48 Obstructive sleep apnea 48 fatigue dizziness nausea 48 Chronic fatigue 48 leaky gut 48 urine leakage 48 confusion disorientation 48 Cortisol 48 obesogenic environment 48 metabolic 48 rhythm disturbances 48 orbital frontal cortex 48 Seasonal Affective Disorder SAD 48 hyperarousal 48 Excessive daytime sleepiness 48 nighttime awakenings 48 inattention hyperactivity 48 Sleep disordered breathing 48 Vigorous exercise 48 muscle wastage 48 Dr. Zoe Arvanitakis 48 QT interval prolongation 48 Mariana Figueiro 48 Iron deficiency anemia 48 recurrent seizures 48 cortical activation 48 involuntary muscle spasms 48 Wernicke Korsakoff syndrome 48 narcolepsy sleep apnea 48 inherit predisposition 48 hippocampal function 48 obstructive sleep apnea 48 serotonin imbalance 48 attentional 48 mood disorders 48 Stressful situations 48 Polysomnographic 48 Gazzaley 48 brainwave patterns 48 magnetic stimulation 48 psychophysiological 48 cognition 48 glutamate signaling 48 endocannabinoid signaling 48 apneic 48 growth hormone secretion 48 digestive discomfort 48 anticholinergic effects 48 male hormone androgen 48 metabolic processes 48 nocturnal hypoglycemia 48 glucocorticoid hormones 48 metabolic abnormalities 48 physiological 48 Sara Mednick 48 Li Huei Tsai 48 Eve Van Cauter 48 overworked overstressed 48 Sleeplessness 48 cardiac abnormalities 48 hypos 48 melatonin secretion 48 synapse formation 48 proprioceptive 48 Dr. Masashi Yanagisawa 48 Posttraumatic stress disorder PTSD 48 breathe shallowly 48 nocturnal enuresis 48 dyskinesias 48 urinary leakage 48 maladaptive behaviors 48 habitual snoring 48 residual confounding 48 abstinent alcoholics 48 overactive bladder symptoms 48 insomnia sleep apnea 48 fructose intake 48 chronic insomniacs 48 acetylcholine neurotransmitter 48 sedating antihistamines 48 Psychosocial interventions 48 stress hormone cortisol 47 vitamin B1 deficiency 47 parasympathetic nervous system 47 postpartum mood 47 sedating antihistamine 47 calorie restriction 47 Fecal incontinence 47 treat narcolepsy 47 binge eating 47 glycogen depletion 47 Overexertion 47 bradykinesia 47 cortisol levels 47 Obsessive compulsive disorder 47 endogenous opioid 47 hypoxemia 47 Louise Hawkley 47 nocebo 47 hormone cortisol 47 Joyce Walsleben 47 impulsiveness hyperactivity 47 painful stimuli 47 arterial stiffening 47 photic 47 melatonin 47 thermogenesis 47 physiological arousal 47 Neuroplasticity 47 Popping pills 47 chronically fatigued 47 Antidepressant medications 47 serotonin 47 restlessness irritability 47 melatonin receptors 47 Frobell 47 eating mindfully 47 EEG readings 47 ramelteon 47 uncontrollable shaking 47 Candida overgrowth 47 artery calcification 47 polyuria 47 homeostatic mechanisms 47 Francine Grodstein 47 da mage 47 thyroid dysfunction 47 airway constriction 47 adiponectin levels 47 Frequent urination 47 endogenous opioids 47 microtrauma 47 probiotic supplementation 47 IBMT 47 depressive relapse 47 airway narrowing 47 jittery Schardt 47 Maternal obesity 47 persistent pulmonary hypertension 47 Estrogen deficiency 47 magnesium intake 47 Moderate drinkers 47 IBS sufferers 47 impulsive behaviors 47 Mood disorders 47 Anxiety disorders 47 SIRT1 protein 47 Postnatal depression 47 catastrophizing 47 hormone serotonin 47 diarrhea bloating 47 Sexual dysfunction 47 leptin 47 caloric expenditure 47 lethargy irritability 47 irregular menstrual cycles 47 M. vaccae 47 satiety signals 47 neurotransmitter serotonin 47 caffeine intake 47 impair fertility 47 sexsomnia 47 fat oxidation 47 Schizophrenics 47 hormonal surges 47 Migraine headache 47 Endel Tulving 47 neuroleptic drugs 47 Sarcopenia 47 postural hypotension 47 dentinal hypersensitivity 47 myelin breakdown 47 overfeeding 47 chemobrain 47 neuropsychiatric disorder 47 delusions hallucinations 47 thermoregulation 47 wakefulness 47 cingulate cortex 47 Behavior modification 47 eat unhealthily 47 lightheadedness dizziness 47 disregulation 47 Neumark Sztainer 47 psychosomatic illnesses 47 ADHD 47 muscle atrophy 47 airway obstructions 47 airflow limitation 47 self injurers 47 Pathological gambling 47 Dopamine agonists 47 basal metabolism 47 Iron deficiency 47 ovarian hormones 47 apnea 47 Leitzmann 47 mitochondrial abnormalities 47 sedating medications 47 metabolic syndrome MetS 47 neurocognitive deficits 47 HPA axis 47 Eltek technologically advanced 47 hedonic adaptation 47 SSRI anti depressants 47 neurodevelopmental 47 yo yo dieting 47 asthmatic airways 47 Hormone imbalance 47 dysrhythmias 47 dysfunction Zada 47 Muscle spasms 47 overactive thyroid gland 47 Decety 47 azoospermia 47 neurologic disorder 47 Untreated sleep apnea 47 Repeated concussions 47 resting metabolic 47 alkalosis 47 premenstrual syndrome PMS 47 QTc interval 47 excessive urination 47 allostatic load 47 endoplasmic reticulum stress 47 satiety cues 47 neurodevelopmental outcomes 47 skeletal muscle mass 47 dysrhythmia 46 anhedonia 46 feeling unrefreshed 46 Gunstad 46 adrenal hormones 46 SAD Seasonal Affective Disorder 46 parkinsonian symptoms 46 caffeine 46 serotonin neurotransmitter 46 hypoglycaemic episodes 46 fluid overload 46 abdominal visceral fat 46 headaches mood swings 46 Sacktor 46 low calorie diets 46 neural degeneration 46 periodontal infections 46 frontal lobe dysfunction 46 delayed gastric emptying 46 hypothalamic pituitary adrenal HPA 46 Snorers 46 dyscalculia 46 nerve degeneration 46 psychic numbing 46 hormone leptin 46 NRF2 gene 46 neuroleptics 46 PBDE exposure 46 gassiness 46 muscle protein synthesis 46 neurobiological 46 Osteoporotic fractures 46 Thyroid hormones 46 Obstructive Sleep Apnea 46 Circadian rhythms 46 unmeasured confounders 46 ventral prefrontal cortex 46 anatomical abnormalities 46 hyperemesis 46 vasovagal syncope 46 somnambulism 46 menstrual irregularity 46 Nutritional deficiencies 46 ventromedial prefrontal cortex 46 hypercapnia 46 obstructive apnea 46 postural stability 46 Breathing exercises 46 mitochondrial oxidative 46 stress hormones 46 calorie dieters 46 pre frontal cortex 46 journal Sleep 46 narrowed airways 46 neuromotor delays 46 Prader Willi syndrome 46 Laura Fonken 46 depressive disorders 46 catecholamine 46 Heavy snorers 46 severe hypoglycemia 46 Hormonal imbalances 46 biological clocks 46 moderate aerobic exercise 46 strenuous exertion 46 Ketosis 46 fructose diet 46 ingestive behavior 46 homeostatic 46 mitochondrial decay 46 hypothalamic pituitary adrenal axis 46 traction alopecia 46 tiredness irritability 46 bodily sensations 46 fatal arrhythmias 46 chronobiology 46 hypopnea 46 cognitive deficits 46 Seth Pollak 46 DHA fatty acid 46 neurotransmission 46 Genetic predisposition 46 autoregulation 46 drowsiness 46 Caloric restriction 46 prolactin levels 46 nocebo effect 46 Vitamin supplements 46 dietary sodium 46 Dr. Aronne 46 Susan Nolen Hoeksema 46 peptide YY 46 Avoid caffeine 46 overweight Mindell 46 cortisol 46 untreated hypothyroidism 46 adenotonsillectomy 46 obstructive sleep apnea OSA 46 Personality traits 46 orexin neurons 46 muscle degeneration 46 adrenal function 46 tetany 46 movement REM sleep 46 hypoglycemia 46 diagnosing ADHD 46 Regular aerobic exercise 46 Sugary foods 46 neurophysiological 46 brain plasticity 46 dysregulation 46 Overfeeding 46 unhealthy dietary habits 46 hypoglycemic coma 46 sensory disturbances 46 electroencephalographic 46 vitamin deficiency 46 vitamin B# deficiency 46 Oral mucositis 46 psychomotor retardation 46 Acid reflux 46 mitochondrial defects 46 hiatus hernia 46 vitamin megadoses 46 Sekerovic 46 circadian disruption 46 drunkorexia 46 serotonin reuptake 46 tonic clonic seizures 46 oxidized cysteine 46 ketosis 46 mood swings irritability 46 Compulsive hoarding 46 neurological abnormalities 46 authors hypothesize 46 bacterial antibiotic resistance 46 neuro degeneration 46 RBP4 levels 46 Physical exertion 46 fluoxetine Prozac 46 neurodevelopment 46 overstimulate 46 Sian Beilock 46 Unhealthy eating habits 46 habituation 46 excitotoxicity 46 hyponatraemia 46 Figueiro 46 Premature menopause 46 overactivated 46 acute psychosis 46 hyperprolactinemia 46 shiftworkers 46 lightheadedness nausea 46 Tschöp 46 ADHD symptoms 46 dietary restriction 46 insomnia irritability 46 Severe acne 46 carbohydrate restriction 46 angina chest 46 affective psychoses 46 metabolic derangements 46 Autoimmune disorders 46 leptin resistant 46 edema swelling 46 Obstructive sleep apnea OSA 46 unprovoked seizures 46 hormonal imbalances 46 EEG biofeedback 46 drowsy driving 46 Chronic constipation 46 neuromotor 46 hippocampal volume 46 QT intervals 45 oncomodulin 45 Kirk Wilhelmsen 45 DQB1 * 45 spine curvature 45 neurological pathways 45 insomnia sufferers 45 overeat 45 temporomandibular joint 45 mania hypomania 45 Sleep apnea 45 excessive perspiration 45 polycystic ovary syndrome PCOS 45 Carskadon 45 brain frontal lobe 45 kalirin 45 CPT1c 45 parasomnia 45 overstimulation 45 Abdominal pain 45 chromium picolinate supplementation 45 thirst urination 45 stathmin 45 Cris Slentz 45 hyperacidity 45 Eunyoung Cho 45 binge eating disorders 45 stimulant medications 45 swallowing reflex 45 auditory neurons 45 autism spectrum disorders ASDs 45 nutritional deficiency 45 Uncontrolled diabetes 45 actigraphy 45 CYP #A# 45 calories expended 45 gastrointestinal disturbances 45 tremors slowness 45 testicular dysgenesis syndrome 45 hormone thyroxine 45 cardiac arrest oxygenated blood 45 Cluster headaches 45 gastric motility 45 amygdalae 45 acetyl L carnitine 45 eating fatty foods 45 REM sleep behavior 45 Muscle cramps 45 tremors rigidity 45 insula activation 45 periodontal infection 45 presenteeism 45 shorten telomeres 45 electrolyte imbalances 45 tic disorders 45 Sexual arousal 45 deformational plagiocephaly 45 activate AMPK 45 olfactory dysfunction 45 muscle cramping 45 swelling edema 45 Daytime drowsiness 45 Seasonal allergies 45 headaches stomachaches 45 nutritional deficiencies 45 undernutrition 45 Dr Idzikowski 45 hippocampal neurogenesis 45 Tryptophan 45 chronic heartburn 45 Adequate vitamin D 45 irregular menstrual periods 45 physiologically 45 circadian clocks 45 Nausea vomiting 45 caffeinated drinks 45 symptom flare ups 45 thigh circumference 45 Birth defects 45 Sensory deprivation 45 physiological mechanisms 45 UM Chronic Pain 45 Degenerative disc disease 45 variant angina 45 oxygen deprivation 45 hyperammonemia 45 cartilage degeneration 45 synaptic plasticity 45 postoperative delirium 45 paranoid hallucinations 45 #,# DCB 45 repolarization 45 painful erections 45 stress induced analgesia 45 nociception 45 fatty acid synthase 45 genetically predetermined 45 circadian clock 45 comorbid disorders 45 autistic traits 45 Kileny 45 ghrelin 45 neurodevelopmental outcome 45 muscle rigidity 45 neuro transmitter 45 grogginess 45 Restless Legs Syndrome 45 Dr. Ronald Chervin 45 Migraine sufferers 45 myotonia 45 carbohydrate metabolism 45 involuntary tics 45 paranoia hallucinations 45 BDNF protein 45 slow twitch fibers 45 stereotypy 45 Exertion 45 nocturia 45 Carpal tunnel 45 thiamin deficiency 45 chronic prostatitis 45 overactive thyroids 45 perioperative complications 45 laryngospasm 45 Low carb dieters 45 euthymic patients 45 GERD symptoms 45 Female Athlete Triad 45 placental hormones 45 malabsorptive 45 Ankle sprains 45 Dr Chris Idzikowski 45 eat cookies Lumeng 45 gallstone formation 45 maladaptive 45 Hypoglycemia 45 intermittent exotropia 45 generalized epilepsy 45 antioxidant supplementation 45 hypokalaemia 45 vivid hallucinations 45 antidepressive 45 somatosensory cortex 45 dietary fats 45 peristalsis 45 hormone secreted 45 diurnal rhythm 45 Systemic lupus 45 hyperactivity inattention 45 Bacterial vaginosis 45 Withdrawal symptoms 45 ROZEREM 45 Hip fractures 45 rhythmicity 45 polydipsia 45 metabolic parameters 45 behave abnormally 45 obsessive compulsive behaviors 45 physiological adaptations 45 cognitive function 45 Sedentary lifestyles 45 musculoskeletal disorders MSDs 45 Thyroid hormone 45 anovulation 45 Mild hypothermia 45 depression irritability 45 cognitive affective 45 neurological impairments 45 gastro oesophageal reflux 45 urinary symptoms 45 prefrontal brain 45 Dr. Burlay 45 headaches backaches 45 microsleep 45 Swithers 45 oxygen desaturation 45 noxious stimuli 45 hypopneas 45 anticipatory anxiety 45 phthalate exposure 45 malabsorption 45 distracter 45 Adam Kuligowski 45 B# deficiency 45 inducing hormone melatonin 45 hyper vigilance 45 type2 diabetes 45 tryptophan depletion 45 cardio respiratory fitness 45 iron deficiency 45 neural pathways 45 androgen excess 45 Barbara Sahakian 45 Neuropathic pain 45 metabolic disturbances 45 tremor rigidity 45 kernicterus 45 peripheral neuropathy nerve 45 narcolepsy cataplexy 45 abnormal lipid levels 45 avoid overexertion 45 nausea constipation 45 cortisol stress 45 overt hypothyroidism 45 Male pattern baldness 45 Delayed Onset Muscle Soreness 45 irregular menstruation 45 gastroesophageal reflux 45 fluid shear 45 Benign Paroxysmal Positional Vertigo 45 positional plagiocephaly 45 unhealthy eating habits 45 obsessive compulsive disorder OCD 45 Caffeine stimulates 45 Cognitive behavioral therapy 45 impair cognitive 45 schizoid personality disorder 45 Suicidal thoughts 45 mental fogginess 45 gastro esophageal reflux 45 folic acid deficiency 45 muscles tendons ligaments 45 disc degeneration 45 thunderclap headache 45 menstrual cramping 45 Genetic variants 45 Rotavirus infections 45 Ghrelin 45 dopamine depletion 45 metacognition 45 slurred speech drowsiness 45 irritability mood swings 45 cardiac autonomic 45 metabolically costly 45 tiredness 45 paranoia delusions 45 psychostimulants 45 cramps nausea 45 throbbing headaches 45 manic episode 45 GERD 45 Vaginal dryness 45 osteoporosis brittle bones 45 retinal bleeding 45 light headedness dizziness 45 Nocturia 45 Separation anxiety 45 spontaneous erections 45 Major depressive disorder 45 Muscle soreness 45 Enlarged prostate 45 neuropeptides 45 malignant hyperthermia 45 eating binges 45 Stickgold 45 hypothalamic pituitary gonadal HPG 45 stochastic resonance 45 declarative memory 45 Sore muscles 45 adenosine receptors 45 unhealthier lifestyles 45 vitamin D inadequacy 45 Hoarseness 45 biorhythms 45 Smaller incisions 45 Shin splints 44 gastric reflux 44 sensory cortex 44 inhaled allergens 44 Behavior Disorder 44 airway reactivity 44 airway collapses 44 carb cravings 44 Overworking 44 satiety fullness 44 overhydration 44 malonyl CoA 44 muscle soreness DOMS 44 biological predisposition 44 prolonged QT interval 44 sleep apneas 44 lethal arrhythmias 44 hormonal disturbances 44 Dr. Kenneth Mukamal 44 Andrew Wyrobek 44 convulsive seizures 44 isometric exercise 44 neuro cognitive 44 causal pathway 44 disordered eating 44 Aerobic exercise 44 spinal curvature 44 term potentiation LTP 44 Migraines 44 unhealthful behaviors 44 nausea diarrhea vomiting 44 inhibitory neurotransmitters 44 headaches nausea vomiting 44 intelligence quotient IQ 44 Vitamin D supplements 44 hormonal 44 sex hormone estrogen 44 stressors 44 Trichopoulos 44 adrenal exhaustion 44 dysfunctional mirror neuron 44 Carpal tunnel syndrome 44 UCP2 44 somnolence sleepiness 44 acamprosate 44 endocannabinoid system 44 asthma flare ups 44 premenstrual symptoms 44 polycystic ovary syndrome